1,721,098 research outputs found
CIRCADIAN RHYTHMS AND THEIR IMBALANCE AS ONE OF THE MECHANISMS OF HEALTH DISRUPTION IN MODERN PEOPLE
No full textGozhenko A. I., Hryshko Yu. M. CIRCADIAN RHYTHMS AND THEIR IMBALANCE AS ONE OF THE MECHANISMS OF HEALTH DISRUPTION IN MODERN PEOPLE. Актуальні проблеми транспортної медицини / Actual problems of transport medicine / 2018;4(54):172-184. ISSN 1818-9385
DOI http://dx.doi.org/10.5281/zenodo.2526928
http://aptm.org.ua
CIRCADIAN RHYTHMS AND THEIR IMBALANCE AS ONE OF THE MECHANISMS OF HEALTH DISRUPTION IN MODERN PEOPLE
A.I. Gozhenko, Yu.M. Hryshko
Ukrainian Medical Stomatological Academy, Poltava
Summary
The paper examines the issues of circadian rhythms functioning and their significance in the regulation of physiological processes. The author discusses the role of physiological biorhythms and melatonin as a universal bioregulator, adaptogen, and stabilizer of the CNS functions. Metabolic circadian rhythms are among the most important processes in the body. The paper analyzes the molecular and genetic aspects of the biological clock and its interrelation with lipid metabolism. The modern views on the biological rhythms of carbohydrate metabolism and its role in the etiology and pathogenesis of diabetes mellitus have been summarized. The influence of circadian rhythms on the LPO parameters has been discussed.
The paper focuses on the issues of desynchronosis, its causes and consequences. The imbalance of circadian rhythms, caused either by external or internal factors, may lead to the disruption of the body’s regulatory systems, which consists in the development of metabolic disorders. This, in its turn, may cause disorders of the modern person’s health.
Key words: circadian rhythms, desynchronosis, melatonin, metabolism
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
INTEGRATION OF PRIVATE BUSINESS PRINCIPLES IN MEDICAL INSTITUTIONS ON THE EXAMPLE OF A BUSINESS MODEL OF ORGANIZATION OF POPULATION'S PLANNED VACCINATION = ІНТЕГРАЦІЯ ПРИНЦИПІВ ПРИВАТНОГО БІЗНЕСУ У МЕДИЧНІ ЗАКЛАДИ НА ПРИКЛАДІ ПОБУДОВИ БІЗНЕС-МОДЕЛІ ОРГАНІЗАЦІЇ ПЛАНОВОЇ ІМУНІЗАЦІЇ НАСЕЛЕННЯ
No full textGozhenko A. I., Gumeniuk A. V., Gumeniuk R. V. INTEGRATION OF PRIVATE BUSINESS PRINCIPLES IN MEDICAL INSTITUTIONS ON THE EXAMPLE OF A BUSINESS MODEL OF ORGANIZATION OF POPULATION’S PLANNED VACCINATION = ІНТЕГРАЦІЯ ПРИНЦИПІВ ПРИВАТНОГО БІЗНЕСУ У МЕДИЧНІ ЗАКЛАДИ НА ПРИКЛАДІ ПОБУДОВИ БІЗНЕС-МОДЕЛІ ОРГАНІЗАЦІЇ ПЛАНОВОЇ ІМУНІЗАЦІЇ НАСЕЛЕННЯ. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2020;4(89):12-17. ISSN 0049-6804.
DOI http://dx.doi.org/10.5281/zenodo.4430734
http://www.herald.com.ua
УДК 614.47:658
DOI http://dx.doi.org/10.5281/zenodo.4430734
INTEGRATION OF PRIVATE BUSINESS PRINCIPLES IN MEDICAL INSTITUTIONS ON THE EXAMPLE OF A BUSINESS MODEL OF ORGANIZATION
OF POPULATION’S PLANNED VACCINATION
A. I. Gozhenko, A. V. Gumeniuk, R. V. Gumeniuk
SE “Ukrainian research Institution for Medicine of Transport”, Odessa;
e-mail: [email protected]
ІНТЕГРАЦІЯ ПРИНЦИПІВ ПРИВАТНОГО БІЗНЕСУ У МЕДИЧНІ ЗАКЛАДИ НА
ПРИКЛАДІ ПОБУДОВИ БІЗНЕС-МОДЕЛІ ОРГАНІЗАЦІЇ ПЛАНОВОЇ
ІМУНІЗАЦІЇ НАСЕЛЕННЯ
А. І. Гоженко, А. В. Гуменюк, Р. В. Гуменюк
ДП Укр НДІ медицини транспорту МОЗ України, м. Одеса
Summary
Denial of vaccination is becoming a problem for countries that intend to close the immunization gap. One in five children in the world does not receive routine immunizations with vital vaccines. The WHO estimates that about 1.5 million children still die each year from diseases that can be prevented with today's vaccines. Vaccination is one of the most effective means of protection against deadly diseases. Objective: to develop a strategy to achieve vaccination coverage, which will help build public confidence in vaccination and health professionals based on the principles of private business and build a business model in the Canvas template. Using the business model in the Canvas template, in the form of nine interconnected blocks, allows the medical institution to clearly describe the activities of the institution and find "bottlenecks" and possible growth points. The peculiarity of the model is the focus of all aspects of the organization's activities on the patient and his needs.
Key words: vaccination of the population; business model in Canvas template; private business
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
THE ROLE OF SYSTEMIC INFLAMMATION IN THE PATHOGENESIS OF METABOLIC DISORDERS. PART I. CONCEPT OF SYSTEMIC INFLAMMATION AND ITS PATHOGENESIS
No full textGozhenko A. I., Hryshko Yu. M., Gramatiuk S. M. THE ROLE OF SYSTEMIC INFLAMMATION IN THE PATHOGENESIS OF METABOLIC DISORDERS. PART I. CONCEPT OF SYSTEMIC INFLAMMATION AND ITS PATHOGENESIS. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2019;3(84):91-100. ISSN 0049-6804.
DOI http://dx.doi.org/10.5281/zenodo.3465995
http://www.herald.com.ua
УДК 616-002:616-098
DOI http://dx.doi.org/10.5281/zenodo.3465995
THE ROLE OF SYSTEMIC INFLAMMATION IN THE PATHOGENESIS OF METABOLIC DISORDERS. PART I. CONCEPT OF SYSTEMIC INFLAMMATION AND ITS PATHOGENESIS
Gozhenko A. I., Hryshko Yu. M., Gramatiuk S. M.
Ukrainian Research Institute for Medicine of Transport of Ukrainian Ministry of Health Care, Odessa;
Ukrainian Medical Stomatological Academy, Poltava;
Limited Liability Company Institute of Cell Biorehabilitation, Kharkіv
e-mail: [email protected].
Summary. In recent years, the concept of systemic inflammation has emerged - as a typical, pathological process. The development of systemic inflammation as a form of response to systemic alteration is accompanied by functional activation of cells of the lymphoreticular system, which is ensured by changes in metabolism, which further causes the development of insulin resistance, type 2 diabetes mellitus (CD2), atherosclerosis resulting from impaired functional-metabolic continuum (FMC), the concept of which has been formulated in recent years, which indicates the relatively constant nature of metabolism and its parameters in the intercellular environment. Thus, in its turn, is closely connected to the functional activity of organs and cells, thus forming a single system – the continuum. It has been shown that along with the well-known systemic manifestations observed in classical inflammation, as a predominantly local process, there are phenomena inherent in the body that are inflammatory but not local but systemic. Further studies should identify systemic inflammation as a distinct typical pathological process.
Key words: systemic inflammation, metabolism, diabetes mellitus, cytokines, insulin resistance
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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