1,721,778 research outputs found

    Introduction to transcription factor structure and function

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    Transcription of eukaryotic genes is regulated by DNA binding proteins known as transcription factors. These factors interact specifically with sequences located in the promoter regions of the genes they regulate. Transcription factors are classified in families according to the structure of their DNA binding domain. Some transcription factor families are present in most eukaryotes, while others are specific of certain lineages, suggesting that they are more recent acquisitions. In addition to the DNA binding domain, transcription factors possess other domains involved in activating or repressing gene expression, dimerization and establishing protein-protein interactions. Transcription factor action is finely modulated by mechanisms involving their synthesis, subcellular location and activity, usually through the interaction with other proteins and/or post-translational modifications. In this chapter, we summarize general properties of eukaryotic transcription factors as an introduction to the specific chapters dealing with the structure and function of plant transcription factors of this book.Fil: Gonzalez, Daniel Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentin

    ALMA-IMF + Single Dish data (B3 + MGPS90, B6 + BGPS)

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    For internal use of the ALMA-IMF consortium. Data will become public with the publication of Díaz-Gonzalez, Daniel Jacobo et al. (2022, in preparation). Version 0.8 contains combination of ALMA-IMF 12m images published in Paper II (Ginsburg et al. 2021) with BOLOCAM GPS for Band 6 (Aguirre et al. 2011, Ginsburg et al. 2013) and MGPS90 for Band 3 (Ginsburg et al. 2020). Combination was done using an adaptation of the uvcombine repository: https://github.com/radio-astro-tools/uvcombine For further inquiries contact: Daniel Jacobo Díaz González, [email protected] Roberto Galván Madrid, [email protected]

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    CAUSAS DE SEPSIS NEONATAL TEMPRANA EN RECIEN NACIDOS PREMATUROS DEL SERVICIO DE NEONATOLOGIA DEL HOSPITAL MATERNO INFANTIL ISSEMYM DURANTE EL PERIODO DEL 01 DE ENERO AL 31 DE DICIEMBRE DEL 2010

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    CONCLUSIONES: las causas maternas de sepsis neonatal temprana se asocian a la ruptura prematura de membranas amnióticas de más de 18 horas de evolución siendo este el grupo más importante de pacientes en total 34 pacientes, con una asociación de un 100%.Seguido de la cérvico vaginitis con 28 pacientes, y las infecciones de vías urinarias con 28 pacientes de 34 pacientes.En cuanto a la corioamnioitis materna solo se documentaron un total de 14 pacientes de 34 pacientes siendo el grupo mas bajo en relación a las causas maternas. En cuanto a las causas neonatales se refiere, el grupo de entre 34- 35 semanas de gestación fue el grupo mas frecuente asociado a sepsis temprana, con un total de 13 pacientes, el peso al nacer el grupo mas vulnerable fue el de 1500-1999 gr. con un total de 16 pacientes, al género se refiere, las pacientes femeninas se asociaron con mayor número con 19 pacientes y 15 pacientes masculinos, la vía de nacimiento fue mayor por cesárea con 29 pacientes.La asfixia neonatal tuvo una asociación muy baja solo 5 pacientes.Y en cuanto a los Hemocultivo, solo 2 se reportaron con germen aislado con una asociación muy baja, y el germen aislado fue Escherichia coliRESUMEN CAUSAS DE SEPSIS NEONATAL TEMPRANA EN RECIEN NACIDOS PREMATUROS DEL SERVICIO DE NEONATOLOGIA DEL HOSPITAL MATERNO INFANTIL ISSEMYM DURANTE EL PERIODO DEL 01 DE ENERO AL 31 DE DICIEMBRE DEL 2010 INTRODUCCIÓN: Sepsis neonatal se refiere a un síndrome clínico caracterizado, por signos sistémicos de infección acompañado de bacteriemia en los primeros 28 días de vida con o sin hemocultivo positivo. La sepsis neonatal de inicio temprano se define como la sepsis que se presenta desde el momento del nacimiento, hasta las 72 horas de vida extrauterina, la enfermedad se puede manifestar como bacteriemia asintomática, sepsis generalizada, neumonía y/o meningitis

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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