40,749 research outputs found
PVD: Gold Nucleation Analysis Lab
No full textThis 2-page lab guide, created by the Nanotechnology Applications and Career Knowledge Support (NACK) Center at Pennsylvania State University, features an online laboratory on gold nucleation analysis that "investigates surface mobility properties and analyze surface nucleation as a result of heat treatment." During the lab, students watch videos on the processing, annealing, and analysis of physical vapor deposition (PVD) gold thin films. Included are 12 student questions to be completed after watching the videos
Rheumatoid arthritis, gold therapy, contact allergy and blood cytokines.
No full textOBJECTIVE: To study the clinical and biochemical effects of a low starting dose for gold therapy in rheumatoid arthritis patients with a contact allergy to gold. METHODS: Serum cytokines were assayed before and 24 h after the first injection of gold sodium thiomalate (GSTM). RESULTS: Contact allergy to gold was found in 4 of 19 patients. Compared to gold-negative patients (starting dose: 10 mg GSTM), there was a larger increase in serum TNFalpha (p < 0.05), sTNF-R1 (NS), and IL-1 ra (p < 0.05) in gold-allergic patients. CONCLUSIONS: Cytokines are released in blood by GSTM in RA patients with gold allergy. To minimize the risk of acute adverse reactions the starting dose of GSTM should be lowered to 5 mg. Alternatively, patients should be patch-tested before gold therapy; in test-positive cases, 5 mg is recommended as the first dose
In powder & crinoline : Preservation Lab Treatment Report
No full textThis book contains illustration by well known illustrator, Kay Nielsen. This is a grey quarter cloth binding with beige paper covered boards. The grey cloth features gold tooling decoration on the spine. This was overall in fair condition when it came to the lab, however the spine was partially torn and the inner joints were weak.View Catalog Record</a
Permanently : Preservation Lab Treatment Report
No full textThis is a 4 volume set of books by author Kenneth Koch, printed by Tiber Press in 1960. This set came to the Preservation Lab for rehousing. The books are in good condition, yet suffer from minor surface dirt. The original slip case designed for the book is missing, but a photo of the original was used as reference.View Catalog Record</a
Sen-Lab-LMS/Senescence_nuclear_features: Publication_version_2.0
No full text<p>Author checklist.</p>
Nanotechnology Principles Lab: Synthesis of Nanoparticles
No full textDescription:This Nanotechnology Principles Lab: Synthesis of Nanoparticles is provided by SHINE: Seattle's Hub for Industry-driven Nanotechnology Education. The &quot;lab consists of activities designed to teach students about the synthesis and applications of gold and silver nanoparticles.&quot; Learning Outcomes are provided for two of the three lab activities included.Learning outcomes for Gold Nanoparticle Sensor lab:To understand and use a bottom-up approach for the synthesis of gold nanoparticlesTo observe the effect of size on optical properties of gold nanoparticlesTo create and test a gold nanoparticle-based &quot;salt sensor&quot;To use this nanoparticle-based sensor to detect the presence of salt in a series of unknownsLearning outcomes for Silver Nanoparticle Antimicrobial Properties lab:Understand that chemical, biological, and physical properties of materials change at the nanoscalePerform a controlled experiment to study the properties of silver nanoparticles including color and antibacterial propertiesUnderstand the reaction taking place to synthesize silver nanoparticlesBecome aware of the ethical debate surrounding nanotechnology and nano-enhanced productsContents:This collection of resources includes a Nanoparticle Synthesis and Applications PowerPoint presentation, three lab activities, and data safety sheets.&nbsp;The Nanoparticle Synthesis and Applications presentation covers topics such as silver nanoparticles, silver nanoparticle products, ethics, the color of gold, salt censors, gold nanoparticles, other gold nanoparticle uses, and more.The three labs included are Antimicrobrial Properties of Nanoparticles, Gold Nanoparticle Sensor, and Stained Glass. Labs may include learning outcomes, Washington EALR Alignment; Oregon Content Standards Alignment; background information; lists of applications, vocabulary, and materials needed; safety information; pre-lab preparations; pre-lab procedures; pre-lab questions, and more. &nbsp;For orientation purposes SHINE_Antimicrobrial Properties of Nanoparticles&nbsp;Lab.pdf&nbsp;is included as a separate attachment and offers a sample of the type of material included in this curriculum.&nbsp;Below is a list of the files contained within the .zip attachment. The size of each file is included in parenthesis.&nbsp;Synthesis of Nanoparticles&nbsp;(8 files, 5.7 MB)Antimicrobial Properties of Nanoparticles (SHINE_Antimicrobial Properties of Nanoparticles Lab.pdf 484 KB)Antimicrobial Properties of Nanoparticles Safety Data Sheets (SDS) (SHINE_Antimicrobial Properties of Nanoparticles SDS.pdf 1.1 MB)Gold Nanoparticle Sensor &nbsp;(SHINE_Gold Nanoparticle Sensor Lab.pdf 416 KB)Gold Nanoparticle Sensor Safety Data Sheets (SDS) (SHINE_Gold Nanoparticle Sensor SDS.pdf 925 KB)Nanoparticle Synthesis and Applications (SHINE_Lectures_Gold and Siver Nanoparticle Synthesis.pptx 552 KB)Chemistry and Art Nanoparticles in Stained Glass Pre-Lab Assignment (SHINE_Nanoparticles in Stained Glass Lab.pdf 1.1 MB)Nanoparticle Stained Glass Safety Data Sheets (SDS) (SHINE_Nanoparticles in Stained Glass SDS.pdf 1.1 MB
Interaction of gold nanoparticles with neurons
No full textIn the last few decades, advances in nanotechnology have resulted in the production and use of inorganic nanoparticles (NPs). These NPs have been used commercially for a range of applications, particularly in the biomedical field, based on their exceptional chemical and physical properties, which are very different to that in the larger scale. Our understanding regarding the NP interaction with the cells following NP exposure, prior to their use it is very important. This was the motivation for the work carried out in this thesis. Initially, the investigation presented in the thesis involved the synthesis of spherical and hollow gold NPs, which were then capped by water soluble organic oligo-ethylene glycol ligand (OEG). The OEG-capped NPs were then functionalised by attaching a specific cell targeting peptide, lysine terminated-Tet1, on their organic corona. The surface modification of the NPs by the aforementioned ligands, was carried out so that the NPs could be employed in the biological investigations carried out in this project. PC12 and SH-SY5Y cells, neuron-like cell lines, were exposed to the synthesised gold NPs, and the fate of these NPs within the cells was studied by using transmission electron microscopy (TEM). The TEM images revealed that spheres and hollow gold NPs were found within the PC12 cells, indicating that they were able to traverse through the cell membrane. Though, the pathway and cellular processes involved could not be specifically defined due to time constrains. Furthermore, the peptide-functionalised NPs targeted the GTb1 receptors which are readily expressed on PC12 and SH-SY5Y cells. Lysine terminated Tet1-functionalised NPs uptake seemed to be greater compared to OEG-capped NPs, and they were transported to the inner part of the cell around its perinuclear region. Nevertheless, further experiments involving fluorescently tagged NPs would give us an inside on the cellular events that take place following NP exposure, over time. In addition, western blot analysis of proteins involved in a cell stress response could give us information whether the cell is under a stress when it is exposed to gold NPs.Furthermore, the application of the hyperspectral darkfield microscope designed by the Muskens group for imaging of single hollow gold NPs on a TEM grid and in a biological sample (with fixed SH-SY5Y cells), was also presented in this Thesis. The low illumination intensity used (<0:5 W/cm2) is a very good aspect of this setup for future studies with living cells and gold NPs. For example, single hollow gold NPs could be used as spectral sensors of a particular cell signalling pathway
Vermischte Schriften, von Friedrich Jacobs .. [Bd. 7] : Preservation Lab Treatment Report
No full textThis is volume seven of a collection of nine volumes belonging to the Classics Library special collections. Volume 2, 5, 6, 7, 8 have been brough to the lab to receive conservation treatment. Volume one has been treated, and the remaining volumes are in library bindings. The five volumes brought to the Preservation lab have different condition issues and will be treated together. All the bindings are similar, a light brown half leather binding with paste paper covering the boards. The paste paper is decorated to resemble a tree calf pattern. There is gold tooling on the spine and the volumes that still have titles, the title is stamped gold on a red or orange leather adhered to the spine of the book. The endbands are brown and whited stripped stuck-on endbands.View Catalog Record: http://uclid.uc.edu/record=b143627
Vermischte Schriften, von Friedrich Jacobs .. [Bd. 8] : Preservation Lab Treatment Report
No full textThis is volume eight of a collection of nine volumes belonging to the Classics Library special collections. Volume 2, 5, 6, 7 ,8 have been brough to the lab to receive conservation treatment. Volume one has been treated, and the remaining volumes are in library bindings. The five volumes brought to the Preservation lab have different condition issues and will be treated together. All the bindings are similar, a light brown half leather binding with paste paper covering the boards. The paste paper is decorated to resemble a tree calf pattern. There is gold tooling on the spine and the volumes that still have titles, the title is stamped gold on a red or orange leather adhered to the spine of the book. The endbands are brown and white stripped stuck-on endbands.View Catalog Record: http://uclid.uc.edu/record=b143627
Boxcar Poems, 1-12 : Preservation Lab Treatment Report
No full textThis is a small hardback meander book containing poems by John Dorsey. According to the colophon, the book was printed as a broadside and folded, torn and bound as a hardback meander book. The text was letterpress printed. Along with the book, there are four advertisement paper cards related to the author and the printing company. These were loosely set inside the book. This book came to the Lab for housing.View Catalog Record: http://uclid.uc.edu/record=b877704
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