4,132 research outputs found
Fractal dimension and Shannon's entropy analyses of the architectural complexity caused by the inflammatory reactions induced by highly crystalline poly(vinyl alcohol) microspheres implanted in subcutaneous tissues of the Wistar rats.
No full textMelhoria do Programa da Atenção aos Usuários com Hipertensão e Diabetes na Unidade Básica de Saúde Tude de Godoy no Município de Dom Pedrito/RS
No full textCOLUMBIE, Maria Ysabel Frometa Melhoria do Programa da atenção aos usuários com hipertensão e deabetes e diabetes na Unidade Básica de Saúde Tude de Godoy no município de Dom Pedrito/RS.. 2015. 53f. Trabalho Acadêmico (Especialização) – Programa de Pós- Graduação em Saúde da Família. Universidade Federal de Pelotas, Pelotas.
A Hipertensão Arterial Sistêmica e Diabetes Mellitus caracterizam-se por serem doenças crônicas não transmissíveis e apresentam lugar de destaque no contexto da transição epidemiológica. Atingem grande parte da população e estão sujeitas a sofrerem influências de vários fatores de risco, os quais podem desencadeá-las ou intensificá-las. Dessa forma, torna-se essencial um acompanhamento adequado dos portadores destas patologias a fim de prevenir ou retardar o surgimento de possíveis complicações que podem afetar negativamente a qualidade de vida desses usuários. O objetivo deste trabalho foi melhorar a atenção à usuários com HAS e DM na Unidade de Saúde da Família (USF) José Tude de Godoy em Dom Pedrito/RS, através da qualificação da assistência, da implantação de um registro específico para essa ação programática e do desenvolvimento de atividades coletivas de promoção à saúde aos usuários da população-alvo. A intervenção foi realizada no período de outubro 2014 a fevereiro 2015, totalizando 16 semanas com objetivos específicos de ampliar a cobertura de acompanhamentos a hipertensos e diabéticos no respectivo programa; melhorar a adesão dos usuários com HAS e DM ao programa; qualificar o atendimento ou usuários com doença crônica de HAS e DM na unidade básica de saúde; melhorar o registro das informações na atenção primaria a saúde ; mapear hipertensos e diabéticos de risco para doença cardiovascular e desenvolver ações de promoção à saúde. Estimamos que haja 472 hipertensos e 102 diabéticos na área adstrita da USF e destes, foram atendidos no período da intervenção 194 usuários hipertensos e 55 usuários diabéticos. Foram desenvolvidas ações nos eixos temáticos de organização e gestão do serviço, monitoramento e avaliação, prática clínica e engajamento público. O trabalho possibilitou a ampliação da cobertura, a melhoria da qualidade da atenção à saúde ou usuários com HAS e DM, embasado nos cadernos de atenção básica do Ministério da Saúde sobre hipertensão e diabetes, além da realização de diversas ações coletivas de promoção à saúde direcionada para ou usuários com HAS e DM da área de abrangência da UBS.
Palavras-chave: Saúde da Família; Atenção Primária à Saúde; Doença Crônica; Diabetes Mellitus; Hipertensão
Entanglement and quantity in quantum space - About quantum measurement (II)
No full textAs a continuation and extension of "quantity in phase space" "quantity in quantum space" is introduced. With that, the disappearing of quantum interference discussed in a previous paper [S. Durr, et al., Nature 395 (1998) 33] is explained in the same spirit as our recent papers [Ren De-Ming, Commun. Theor. Phys. (Beijing, China) 41 (2004) 685, 833].Physics, MultidisciplinarySCI(E)中国科学引文数据库(CSCD)1ARTICLE133-364
Sneutrino DM in the NMSSM with inverse seesaw mechanism
No full textIn supersymmetric theories like the Next-to-Minimal Supersymmetric Standard Model (NMSSM), the lightest neutralino with bino or singlino as its dominant component is customarily taken as dark matter (DM) candidate. Since light Higgsinos favored by naturalness can strength the couplings of the DM and thus enhance the DM-nucleon scattering rate, the tension between naturalness and DM direct detection results becomes more and more acute with the improved experimental sensitivity. In this work, we extend the NMSSM by inverse seesaw mechanism to generate neutrino mass, and show that in certain parameter space the lightest sneutrino may act as a viable DM candidate, i.e. it can annihilate by multi-channels to get correct relic density and meanwhile satisfy all experimental constraints. The most striking feature of the extension is that the DM-nucleon scattering rate can be naturally below its current experimental bounds regardless of the higgsino mass, and hence it alleviates the tension between naturalness and DM experiments. Other interesting features include that the Higgs phenomenology becomes much richer than that of the original NMSSM due to the relaxed constraints from DM physics and also due to the presence of extra neutrinos, and that the signatures of sparticles at colliders are quite different from those with neutralino as DM candidate.National Natural Science Foundation of China (NNSFC) [11575053]SCI(E)ARTICLE1
Classical mechanics and quantum mechanics
No full textThe Newton equation of motion is derived from quantum mechanics.Physics, MultidisciplinarySCI(E)中国科学引文数据库(CSCD)2ARTICLE5685-6884
Modelo experimental de diabetes mellitus e doença renal associados em camundongos
No full textChronic non-communicable diseases such as Diabetes Mellitus (DM), affect an important part of the population. DM is a lipoprotein metabolic disorder, characterized by hyperglycemia, resulting from an insufficient or deficient secretory response of the hormone insulin, and is still one of the main causes of Kidney Disease (KD). Given the severity of the microvascular complications caused by DM, as well as, cardiomyopathy, encephalopathy, retinopathy, neuropathy and nephropathy, this study was justified. The aim of this study was to associate the models of DM and KD in mice. Sixty-four adult female mice (Mus musculus) of the Swiss strain were used, weighing approximately 20 g, were divided groups: G1, control (n=32) and G2, associated diseases (n=32). First the G2 animals were induced to arteriovenous stenosis (ischemia, 10 minutes and reperfusion) of the left kidney, being observed for 14 days, before receiving streptozotocin (STZ and diet. After this period, STZ was administered at a dose of 150 mg/kg, intraperitoneally, and aqueous glucose solution (10%), for 24 hours, followed by a high-fat diet for 7 days. The evolution of KD was observed using a urine analysis test strip and DM by analyzing blood glucose on a digital glucose monitor. Ischemia and reperfusion were verified by observing changes in color during surgery, volume and size of the left kidney, when compared to the contralateral kidney. Initial renal alterations were observed in G2, in the first 14 days, increased urinary density, pH alteration, presence of glucose, proteins and leukocytes, when compared to G1. DM was confirmed by the presence of hyperglycemia, starting at 200 mg/dL, on the 7th day of induction. G2 animals showed constant weight loss when compared to G1. It was possible to induce and confirm associated DM and KD, with low mortality and easy execution.As doenças crônicas não transmissíveis, como a Diabetes Mellitus (DM), acometem uma parcela importante da população. A DM trata-se de uma desordem metabólica lipoproteica, caracterizada pela hiperglicemia, decorrente da resposta secretória insuficiente ou deficiente do hormônio insulina, sendo ainda uma das principais causas para a Doença Renal (DR). Diante da gravidade das complicações microvasculares causadas pela DM, assim como cardiomiopatia, encefalopatia, retinopatia, neuropatia e nefropatia, justificou-se a realização deste estudo. O objetivo deste estudo foi associar modelos de DM e DR em camundongos. Foram utilizados 64 camundongos (Mus musculus), adultos, fêmeas, da linhagem Swiss, pesando em média 20 g, distribuídos em grupos: G1, controle (n=32) e G2, doença associada (n=32). Primeiramente, foram induzidos à estenose arteriovenosa (isquemia, 10 minutos e reperfusão) do rim esquerdo os animais do G2, sendo observados por 14 dias, antes de receberem estreptozotocina (STZ) e dieta. Após esse período foi administrado STZ, na dose de 150 mg/kg, via intraperitoneal, e solução aquosa de glicose (10%), por 24 horas, seguida de dieta hiperlipídica por 7 dias. A evolução da DR foi observada utilizando-se tira teste de análise urinária e da DM por meio da análise de glicemia em monitor digital glicêmico. Foi constatada a isquemia e reperfusão, mediante observação das alterações de coloração, durante a cirurgia, volume e tamanho do rim esquerdo, quando comparado ao rim contralateral. Observou-se alterações renais iniciais em G2, nos primeiros 14 dias, aumento da densidade urinária, alteração do pH, presença de glicose, proteínas e leucócitos, quando comparados ao G1. A DM foi constatada pela presença de hiperglicemia, a partir de 200 mg/dL, no 7º dia da indução. Os animais do G2 apresentaram perda constante de peso, quando comparados ao G1. Foi possível induzir e confirmar DM e DR associados, com baixa mortalidade e fácil execução
Policy-driven Data Sharing over Attribute-Based Encryption supporting Dual Membership
No full textAttribute-Based Encryption (ABE) plays an important role in current secure data sharing through fine-grained customizable policies. However, the existing ABE schemes only support simple predicates, = and ≠, but cannot express a more general membership predicates, ∈ and ∉, in policies. The low expressivity of ABE will enlarge the ciphertext storage and reduce the communication efficiency. To overcome this problem, we propose an ABE supporting Dual Membership (DM-ABE). The core problem for implementing this scheme is how to use cryptographic methods to decide the membership between the verified element and the given set. In order to solve this problem, we design a cryptographic algorithm, called Secure Decision of Membership (SDM), based on aggregation functions. In this algorithm, any set can be aggregated into one cryptographic element, and the verified element and the given set can be converted into another cryptographic element in decision process. The membership between them can be decided by the above two cryptographic elements. Furthermore, we construct the DM-ABE by using SDM. Because of the good expressivity of our DM-ABE, we further propose a novel cryptographic data sharing framework by integrating DM-ABE and attribute-based access control to provide fine-grained access control and security protection for private data. In the security proof of DM-ABE, we prove that the DM-ABE satisfies the semantic security against chosen-plaintext attacks under the DBDHE assumption in the standard model through a unified way, considering both two encryption methods for ∈ and ∉ at the same time. Finally, we analyze our scheme in terms of time and space complexity, and compare it with some existing schemes. The results show that our DM-ABE has a better expressive ability on the boolean logic of general membership predicates, ∈ and ∉.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Cyber Securit
Constraining the Inner Galactic DM Density Profile with H.E.S.S.
No full text© 2024 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).In this short review, corresponding to a talk given at the conference “Cosmology 2023 in Miramare”, we combine an analysis of five regions observed by H.E.S.S. in the Galactic Center, intending to constrain the Dark Matter (DM) density profile in a WIMP annihilation scenario. For the analysis, we include the state-of-the-art Galactic diffuse emission Gamma-optimized model computed with DRAGON and a wide range of DM density profiles from cored to cuspy profiles, including different kinds of DM spikes. Our results are able to constrain generalized NFW profiles with an inner slope ≳1.3 . When considering DM spikes, the adiabatic spike is completely ruled out. However, smoother spikes given by the interactions with the bulge stars are compatible if ≲0.8 , with an internal slope of sp-stars=1.5.This work has been supported by the grants PID2021-125331NB-I00, PID2022-139841NB-I00, and CEX2020-001007-S, funded by MCIN/AEI/10.13039/501100011033, by “ERDF A way of making Europe”, and the MULTIDARK Project RED2022-134411-T. The author’s contribution to this work has been supported by the FPI Severo Ochoa PRE2021-099137 grant.With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2020-001007-S).Peer reviewe
Diabetes mellitus (DM) related lower extremity amputations (LEA) rate and risk factors.
No full textAuthor: Ieva Vasiliūtė Title: Diabetes mellitus (DM) related lower extremity amputations (LEA) rate and risk factors. Aim: To investigate LEA rate and risk factors in patients with DM. Objectives: To evaluate DM related LEA rate. To determine DM related LEAs levels and patients demographic factors relation. To determine DM related LEAs levels and type of DM relation. To determine DM related LEAs levels and DM duration, body mass index (BMI), glycated hemoglobin (HbA1c) meanings relation. To evaluate expected mathematically based risk factors. Methods: Retrospective medical records study of 153 patients with DM, who underwent LEAs at the Hospital of Lithuanian University of Health Sciences Kaunas clinics was performed during the 2012 01 01 – 2014 12 31 period. Statistical analysis was performed using the standard SPSS 20.0 program. Results: 33,33% of legs amputations occured among people with DM and 66,67% of them were male (p<0,001). Major LEAs were performed mostly in patients with type 2 DM (86,96%) than those with type 1 DM (p<0,001). Male patients LEAs were performed in patients suffering for shorter duration of DM than in women (19,18 m. (±95% PI 16,71-21,65) vs. 23,36 m. (±95% PI 20,07-26,65), p=0,053). Patients with type 2 DM underwent LEAs had DM for shorter durations (16,19 m. (±95% PI 14,32-18,06)) than those with type 1 DM patients (31,43 m. (±95% PI 28,40-34,45)) ( p<0,001). Major LEAs remove patients had BMI (32,86±5,55 kg/m2) than minor LEAs remove patients (29,13±5,91 kg/m2) (p=0,027). No significant relation was found with amputation level and HbA1c average (p=0,246). DM related eye damage increases the risk of minor LEAs 3,10 times (p=0,001). Obesity/overweight the risk of major LEAs increases 5,65 times (p=0,036) and 2,56 times with obliterate atherosclerosis (p=0,006). Patients with type 2 DM have a 3,2 times (p=0,002) higher risk of undergoing major LEA. Conclusions: A third of patients who had undergone LEAs had DM. Amputations were carried out more frequently in men. DKA arose more often in patients with type 2 DM. LEAs were performed a shorter duration male DM patients. Type 2 DM patients suffered LEAs nearly 2 times shorter duration. Major LEAs experienced patients had a higher BMI. The average of HbA1c is not significantly related with amputation levels. DM related eye damage increases the minor LEAs risk by 3,10 times. Obesity/being overweight increases the risk of major LEAs 5,65 times, obliterate atherosclerosis - 2,56 times. Patients with type 2 DM have a 3,2 times higher risk of major LEA
Aktive Übungen zur Reduzierung des Lymphoedems nach Brustkrebsbehandlung
No full textThe aim of this study was to evaluate the reduction in volume of arm lymphedema secondary to breast cancer therapy utilizing an exercise facilitating device. Twenty-one women with arm lymphedema resulting from the surgical and radiotherapeutic treatment of breast cancer were randomly selected. Evaluation was made by water-displacement volumetry before and after each session. The patients were submitted to a series of active exercises using a facilitating device for four 12-minute sessions with intervals of 3 minutes between sessions in the sitting position with alignment of the spinal column. The lymphedematous arm was maintained under compression using a cotton-polyester sleeve. The active exercising device used was a mobile flexion bar fixed on a metal base at a height of 30 cm from the tabletop and at a distance of 10 cm from the patient's body. The paired t-test was utilized for statist ica l analysis with an alpha error of 5% (p-value er Irrtumswahrscheinlichkeit von 5% (p 2.023,0 ml mit einer mittleren Flüssigkeitsverdrängung von 66,9 ml (p<=0,001).Die aktive Übung mit einem einfachen Gerät kann eine signifikante Reduktion des Lymphoedems der Arme bewirken
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