1,721,014 research outputs found
Semeiotica chirurgica. Metodologia, clinica e terapia.
No full text...Il compendio Semeiotica Chirurgica � Metodologia, Clinica e Terapia - non vuole limitarsi a rappresentare una sorta di riordinamento delle nozioni classiche, sono state affrontate le diverse tematiche fisiopatologiche alla luce delle più recenti acquisizioni della letteratura scientifica internazional
A characteristic type of retinal microvascular abnormalities in a patient with neurofibromatosis type 1
No full textThis study aims to describe a typical retinal microvascular abnormality in patients with neurofibromatosis type 1 (NF-1).
A 64-year-old man with diagnosis of NF-1 was evaluated by complete ophthalmological examination, including fluorescein angiography and spectral Domain OCT in Near-Infrared (NIR-OCT) modality. Slit lamp exam showed the presence of more than 10 Lisch nodules for each eye. Ophthalmic examinations and NIR-OCT scans showed the presence of retinal tortuous vessels ending in a ‘puff of smoke’ arrangement. The clinical significance as diagnostic and prognostic factor of this novel type of retinal microvascular abnormality in NF-1 should be further investigate
Two rare diseases in the same patient: Neurofibromatosis type 1 and Madelung's disease
No full textNo abstract available
Juvenile myelomonocytic leukemia in a patient with neurofibromatosis type 1 and xanthogranulomas
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Lichen sclerosus and hidradenitis suppurativa. two case reports of a new possible association
No full textWe report the cases of two women affected by lichen sclerosus also having clinical signs of hidradenitis suppurativa. Lichen sclerosus is a chronic autoimmune disease, in which activated fibroblasts produce significantly altered collagen leading to fibrosis Hidradenitis suppurativa is a chronic relapsing inflammatory disease affecting folliculopilosebaceous unit and apocrine gland, which lesions are nodules and abscesses. The association between lichen sclerosus and autoimmune disorders is well known, but not the one with hidradenitis suppurativa. We present two case reports of these unusual comorbidities
Juvenile xanthogranuloma in neurofibromatosis type 1. Prevalence and possible correlation with lymphoproliferative diseases: experience of a single center and review of the literature
Full text linkNeurofibromatosis type 1 (NF1), is a rare genetic disorder that may involve almost every organ system in the body such as cutaneous, ophthalmologic and central and peripheral nervous system. Cutaneous findings are usually the first sign of the disease. In this study, we investigate the real prevalence of xanthogranulomas juvenile (JXG) and possible correlation with lymphoproliferative diseases. This is a retrospective study conducted on a population with NF1 followed by February 1983 to February 2022 at the "Sapienza" University of Rome, Italy. We investigate the real prevalence of juvenile xanthogranuloma in NF1 and possible correlation with lymphoproliferative diseases. JXG was present in 39 cases (3.1%). JXG is more frequent in NF1 than in the general population while the possible association with lymphoproliferative diseases in NF1 remains controversial
Concomitant segmental vitiligo and segmental morphea in an 8-year-old boy
Full text linkSegmental vitiligo (SV) and segmental morphea are unilateral cutaneous disorders, with an autoimmune pathogenesis. The association of the two generalized forms has been largely reported, while the combination of the two segmental variants is uncommon
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