175 research outputs found

    Arturo Montori de Céspedes (1878-1931), pedagogo imprescindible en Cuba

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    Arturo Montori de Céspedes es una de las figuras más relevantes en la pedagogía cubana en las décadas iniciales de la etapa republicana, su labor como maestro, pedagogo, publicista e investigador fecundo en diversas problemáticas, más su constante interés por analizar el deterioro de la escuela cubana y buscar remedio a los problemas existentes, constituye una página de imprescindible estudio y afán por comprender todo lo que hemos avanzado y lo que nos falta en el camino por la calidad de la educación en Cuba y en la región iberoamericana. Se caracteriza la trayectoria de Montori, ilustrada con fotos y el autor aborda una valiosa intervención que hiciera en Cienfuegos, en 1920, y que se titula: El problema de la educación nacional. PALABRAS CLAVE: Arturo Montori, pedagogo destacado en Cuba. Arturo Montori de Céspedes (1878-1931), essential pedagogue in Cuba ABSTRACT Arturo Montori de Céspedes is one of the most important figures in Cuban pedagogy in the early decades of the Republican period, his work as a teacher, pedagogue, publicist and prolific researcher on various issues, plus his constant interest in analyzing the deterioration of school Cuban and seek remedy existing problems, is a page of essential study and desire to understand everything we have come and what we need in the way the quality of education in Cuba and in the Latin American region. Montori path is characterized, illustrated with photos and author addresses a valuable intervention to do in Cienfuegos in 1920, and entitled: The problem of national education. KEY WORDS: Arturo Montori, a leading educator in Cuba Recibido: marzo 2015      Aceptado: junio 201

    The treatment of peritoneal carcinomatosis in advanced gastric cancer: State of the art

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    Gastric cancer (GC) is the fourth most common cancer and the second leading cause of cancer death in the world; 53-60% of patients show disease progression and die of peritoneal carcinomatosis (PC). PC of gastric origin has an extremely inauspicious prognosis with a median survival estimate at 1-3 months. Different studies presented contrasting data about survival rates; however, all agreed with the necessity of a complete cytoreduction to improve survival. Hyperthermic intraperitoneal chemotherapy (HIPEC) has an adjuvant role in preventing peritoneal recurrences. A multidisciplinary approach should be empowered: the association of neoadjuvant intraperitoneal and systemic chemotherapy (NIPS), cytoreductive surgery (CRS), HIPEC, and early postoperative intraperitoneal chemotherapy (EPIC) could increase the rate of completeness of cytoreduction (CC) and consequently survival rates, especially in patients with Peritoneal Cancer Index (PCI) ≤6. Neoadjuvant chemotherapy may improve survival also in PC from GC and adjuvant chemotherapy could prevent recurrence. In the last decade an interesting new drug, called Catumaxomab, has been developed in Germany. Two studies showed that this drug seems to improve progression-free survival in patients with GC; however, final results for both studies have still to be published. © 2014 Giulia Montori et al

    Intraperitoneal chemotherapy for ovarian cancer with peritoneal metastases, systematic review of the literature and focused personal experience

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    Epithelial ovarian cancer (EOC) causes 60% of ovarian cancer cases and is the fourth most common cause of death from cancer in women. The standard of care for EOC includes a combination of surgery followed by intravenous chemotherapy. Intraperitoneal (IP) chemotherapy (CT) has been introduced into the therapeutic algorithm of EOC with positive results. To explore existing results regarding intraperitoneal chemotherapy a systematic review of the literature and an analysis of our own institutional prospective database of patients treated with cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC) for EOC at different stages were conducted. The focused report concerning our personal experience with advanced EOC treated with cytoreductive surgery and HIPEC produced the following results: In 57 patients cisplatin + paclitaxel as HIPEC was the only significant factor improving overall survival (OS) at multivariate analysis (OR 6.54, 95% CI: 1.24-34.47, P=0.027). Patients treated with HIPEC cisplatin + paclitaxel showed a median OS of 46 months (SD 6.4, 95% CI: 33.4-58.6), while patients treated with other HIPEC regimens showed a median OS of 12 months (SD 3.1, 95% CI: 6.0-18.0). The 2y-OS was 72% and 3y-OS was 68% for cisplatin + paclitaxel as HIPEC, while the 2y- and 3y-OS was 0% for other HIPEC regimens. Patients treated with HIPEC cisplatin + paclitaxel showed a median disease-free survival (DFS) of 13 months (SD 1.6, 95% CI: 9.9-16.1), while patients treated with other HIPEC regimens showed a median DFS of 8 months (SD 3.1, 95% CI: 1.9-14.1). In conclusion, HIPEC cisplatin + paclitaxel in ovarian cancer showed positive results that may be considered semi-definitive according to the level of evidence and should be considered a starting point for further investigations. At present HIPEC cisplatin + paclitaxel should be proposed to patients with advanced ovarian cancer as standard treatment at almost all stages of disease. Platinum + taxane-based intraperitoneal regimens demonstrated superior results compared to other regimens

    What Kind of Iconoclast Was Milton? Monuments, Books, and Textual Immortality

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    Whilst there is ample evidence of Milton's engagement with iconoclasm in his prose and poetry, the English author did not smash paintings and images under a hammer or a crowbar. Furthermore, elsewhere in his writing, Milton resorted to iconicity as a vehicle to represent his poetry. How should we then interpret his fascination with funeral monuments, which were often the object of Puritan iconoclasm? What kind of iconoclast was Milton? Is it possible to reconcile his iconoclastic and iconic impulses? This paper attempts to answer these questions by eventually addressing Milton’s conception of printed books as monuments that preserve and convey the quintessence of the author’s soul beyond life

    Silenzi materici

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    Il saggio riporta i contenuti della conferenza tenuta il 3/3/2015 presso la facoltà di Architettura di Valle Giulia della Sapienza.Il tema centrale è quello del rapporto tra memoria e paesaggio. Che cosa è l'identità di un luogo? E' la domanda dalla quale prende avvio una riflessione critica sul paesaggio che arriva ad analizzare tre memoriali, luoghi emblematici per la celebrazione della memoria

    Laparoscopic lavage versus resection in perforated diverticulitis with purulent peritonitis: a meta-analysis of randomized controlled trials

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    Purulent peritonitis from acute left colon diverticulitis is a relatively common presentation of diverticular disease; historically the treatment was the Hartmann procedure. Laparoscopic peritoneal lavage has been proposed as a lesser invasive treatment option with great interest and debate among surgeons and with contrasting results. The aim of this meta-analysis was to compare the results of sigmoid resection with laparoscopic lavage

    The treatment of peritoneal carcinomatosis in advanced gastric cancer: state of the art

    No full text
    Gastric cancer (GC) is the fourth most common cancer and the second leading cause of cancer death in the world; 53-60\% of patients show disease progression and die of peritoneal carcinomatosis (PC). PC of gastric origin has an extremely inauspicious prognosis with a median survival estimate at 1-3 months. Different studies presented contrasting data about survival rates; however, all agreed with the necessity of a complete cytoreduction to improve survival. Hyperthermic intraperitoneal chemotherapy (HIPEC) has an adjuvant role in preventing peritoneal recurrences. A multidisciplinary approach should be empowered: the association of neoadjuvant intraperitoneal and systemic chemotherapy (NIPS), cytoreductive surgery (CRS), HIPEC, and early postoperative intraperitoneal chemotherapy (EPIC) could increase the rate of completeness of cytoreduction (CC) and consequently survival rates, especially in patients with Peritoneal Cancer Index (PCI) \leq6. Neoadjuvant chemotherapy may improve survival also in PC from GC and adjuvant chemotherapy could prevent recurrence. In the last decade an interesting new drug, called Catumaxomab, has been developed in Germany. Two studies showed that this drug seems to improve progression-free survival in patients with GC; however, final results for both studies have still to be published

    Early goal-directed treatment versus standard care in management of early septic shock: Meta-analysis of randomized trials

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    Since the incorporation of the early hemodynamic resuscitation in septic shock according to the early goal-directed therapy (EGDT) protocol among the 6-hour resuscitation bundle of the Surviving Sepsis Campaign guidelines, a great debate has been raised about the issue. The present meta-analysis aims to determine whether the resuscitative phase really takes advantages by being performed with EGDT

    Pneumoretroperitoneum and Pneumomediastinum Revealing a Left Colon Perforation

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    Left colon perforation usually occurs in complicated diverticulitis or cancer. The most frequent signs are intraperitoneal abscess or peritonitis. In cases of retroperitoneal colonic perforation, diagnosis may be difficult. A 59-year-old woman presented with left thigh pain and with abdominal discomfort associated with mild dyspnea. Computed tomography scan showed air bubbles and purulent collection in the retroperitoneum, with subcutaneous emphysema extending from the left thigh to the neck. Computed tomography scan also revealed portal vein gas and thrombosis with multiple liver abscesses. An emergency laparotomy revealed a perforation of the proximal left colon. No masses were found. A left colectomy was performed. The retroperitoneum was drained and washed extensively. A negative pressure wound therapy was applied. A second-look laparotomy was performed 48 hours later. The retroperitoneum was drained and an end colostomy was performed. Intensive Care Unit postoperative stay was 9 days, and the patient was discharged on the 32nd postoperative day. Pneumoretroperitoneum and pneumomediastinum are rare signs of colonic retroperitoneal perforation. The diagnosis may be delayed, especially in the absence of peritoneal irritation. Clinical, laboratory, and especially radiologic parameters might be useful. Surgical treatment must be prompt to improve prognosis
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