384 research outputs found
Recombinant human granulocyte colony-stimulating factor and neutrophil phenotype.
No full textNo abstract availabl
Chiesa Cattolica e Comunità Europea nell’insegnamento di Giovanni Paolo II
No full textIl contributo, nel quadro del tema generale del volume dedicato a Giovanni Paolo II: legislatore della Chiesa, affronta in particolare l'attività del Papa "legislatore" ed il ruolo dei codici dallo stesso promugati nell'ambito dello sviluppo e consolidamento dell'Unione Europea. Alcune riflessioni sono altresì dedicate alla dibatutta questione delle radici cristiane d'Europa
Manuale di Ematologia per gli studenti di Medicina. Genova, ECIG, III Edizione, ISBN 978-88-7544-223-1
No full textApplications of flow cytometry in the study of human neutrophil biology and pathology.
No full textFlow cytometry represents an interesting methodologic approach to human neutrophil biology and pathology. Several aspects of neutrophil activation can be evaluated by flow cytometry: phagocytosis, respiratory burst (superoxide anion generation, intracellular hydrogen peroxide production), intracellular pH, actin polymerization, membrane potential, aggregation, cytotoxicity, degranulation, and surface marker expression. In several instances whole blood methods have been developed and have been shown to be very specific and sensitive. Neutrophils can easily be distinguished from other circulating cells, including eosinophils, and methods for the evaluation of neutrophil phagocytosis and hydrogen peroxide production are currently used. In addition whole blood procedures for the determination of the expression of neutrophil function-associated surface antigens have been recommended in order to avoid the artifactual changes resulting from isolation methods. Purified neutrophil have to be used to study other parameters such as actin polymerization and cytotoxicity. Flow cytometry permits a multiparametric evaluation of neutrophil functions, and advances in software technology facilitate a wide variety of choices for the handling, storage, and evaluation of data. The applications of flow cytometry in human neutrophil diseases include the diagnosis of chronic granulomatous disease and leukocyte adhesion syndrome types 1 and 2, and the evaluation of granulocyte biology in several clinical conditions such as immunodeficiency conditions, recurrent infections, hematologic diseases, and noninfectious diseases caused by uncontrolled neutrophil activation
Treatment of autoimmune neutropenia with recombinant human granulocyte colony-stimulating factor.
No full textNo abstract availabl
The neutrophil granulocyte in chronic myeloid leukemia.
No full textThe various functional, morphological, structural and enzymatic abnormalities, which can frequently be detected in neutrophil granulocytes from chronic myeloid leukemia (CML) patients, have been reviewed. The analysis of the relevant literature has been made, taking into account the kinetic anomalies displayed by the CML myeloid cells at the various stages of maturation. A conclusion is presented which supports previously suggested hypotheses on how CML circulating neutrophils may have not reached full maturation during their stay in the bone marrow post-mitotic pool, even if they appear to be morphologically mature
Famiglia e diritto nel magistero di Giovanni Paolo II. Proposte per il Sinodo sulla famiglia
No full textRiflettere sulla solidarietà inter-generazionale e passare dalle politiche solo settoriali ad una politica globale, sono gli insegnamenti che Giovanni Paolo II lascia all'umanità, insieme al valore del matrimonio esaltato in entrambi i suoi profili (unitivo e procreativo). Oggi più di ieri occorre garantire specificità e centralità al ruolo della famiglia fondata sul matrimonio tra un uomo ed una donna ed il suo ruolo nella tenuta sociale ed economica della nostra società
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