91 research outputs found
Езопова басна код Доситеја Обрадовића
No full textThe potential and intrinsic polysemy of the esopic fable made a very flexible means of lively expression over the centuries, as evidenced by the fortune it enjoyed in the traditions of many countries: so was in the literature of the southern Slavs, full of evidences the book tries to bring to light. Bearing multiple messages and meanings, a banner of other literary genres, the classical fable lived an unusual flourishing in the eighteenth century, thanks to its versatility and its didactic-didascalic functions. From the categories of the classical tradition Obradović fable comes out revived and renewed: its centrality, in the author's production, is gathered by the youth writings in which few and essential features already highlight all the didactic and illustrative potentialities: the Basne collection becomes the privileged means of entrusting the message and communicating with a wide audience, a space in which the author can disclose himself to the ideas of the Age of the Enlightenment
A proposito di alcune citazioni della “Vita di Feodosij”
No full textThe present work investigates the structure and the process of adaptation of some scriptural references from the New Testament in the Life of Feodosij Pečerskij. In the vast scriptural repertoire the loci chosen for the analysis gather around a few of the numerous themes, milestones of the monk’s spiritual life. Among the forms of citations and references, moreover, some similitudes and analogies were considered, in which, in addition to the persistent semantic and linguistic connections with the source text, we looked at the user and the possible intentions of the author in the process of building the exemplum
Cicerone, Seneca, Giovenale in un saggio sul destino umano.
No full textThe present work intends to investigate the chapter on the old age of Blago Cara Radovana, one of Jovan Ducˇic ́ proses (1926) where the classical spiritual heritage merges into the meditations of a modern man: never as in this work the Serbian writer cites so explicitly his sources: Cicero with the Cato Maior dialogue De Senectute, the XII Letter to Lucilius by Seneca, the X Satire by Juvenal. The contribution attempts to compare some serbian and latin excerpts, echoed not slavishly, but rielaborated by the author through simplifying and omitting, in order to clarify even better his own positions, and coming to conclusions, sometimes discordant from his latin models. The examples of the ancient world, harbingers of a lasting knowledge, are here used as a traditional rhetorical tool, giving to his reasoning a plastic-figurative effect
Un'incursione nel thriller: Poslednja knjiga di Zoran Živković
No full textThe contribution will analyze some of the original features of Poslednja Knjiga (The last book) by Zoran Živković, who does not follow the strict tradition of crime - novels, on the contrary, wishing to transcend reality, the writer overcomes the restrictions of logic and scientifically proved, in order to venture into dimension of the imagery, surreal, dreamy. Živković sets his crime story in a library in Belgrade: inspector Dejan Lukić is entrusted with the case of mysterious deaths, but the investigation, with dramatic turns of events, ends up in a complete nonsense. The truth does not lie in the detection of the murderer (the last book), it is elsewhere, in the mind of the almighty creator - the Author himself, who manipulates the ephemeral lives of his characters. Rich in meta-crime elements, the crime story reveals the complex interaction between the writer's and his creatures' universe
„Teško nama ženama [...]”: la questione femminile in „Tergovci”
No full textThe relation between fathers and children is one of the ideological points of the play chosen by E. Janković, according to the parameters of a bourgeois and mercantile society looking at a useful and modern education and instruction, organic to the needs of the community. The pedagogical commitment of the author from Novi Sad could not ignore some considerations on the key role played by women in the organization of society as a girl, wife and mother, that was to be redefined on the basis of new demands during the 18th century. Goldoni tried to deal with the debate on female education thanks to the lively confrontation between Giannina and Beatrice, being the first model of educated and learned woman, and the latter, prototype of domestic virtue modeled on ancient customs. Behind the comparison between the two figures, Goldoni couldn’t neglect a burning issue of the Enlightment between progressive openness and conservative positions concerning the female question. The work aims at analyzing the two characters in a dialogic interaction that seems to reveal, in the Italian text, a dialectic of opposing models, shaped by Janković in ambivalent and complementary forms. The choice made by Janković, to translate a comedy where the woman is revaluated, by presenting her as main character and by focusing on the problem of her education and instruction, is one of the values of his enlightened program
Management of oral chronic pharmacotherapy in patients hospitalized for acute decompensated heart failure
No full textAcute decompensated heart failure (ADHF) is the most common cause of cardiovascular hospitalization. The presentation is characterized by different clinical profiles due to various underlying causes, volume balance and tissue perfusion status. Currently, a variety of pharmacological therapies, including diuretics, betablockers, ACE-inhibitors, angiotensin receptor blockers and digoxin, are usually prescribed in order to treat chronic heart failure (HF) syndromes caused by left ventricular systolic dysfunction. Despite the large number ofHF patients with frequent hospitalizations for decompensation, only a fewstudies have evaluated the management of oral chronic therapies in the clinical setting of ADHF. This article summarizes the information derived from the few published trials on this subject and a therapeutic approach is suggested with respect to the continuation, dose modification or suspension of oral medications. © 2014 Elsevier Ireland Ltd. All rights reserved
Activity of AMP2041 against human and animal multidrug resistant Pseudomonas aeruginosa clinical isolates
No full textBackground: Antimicrobial resistance is a growing threat to public health. Pseudomonas aeruginosa is a relevant
pathogen causing human and animal infections, frequently displaying high levels of resistance to commonly used
antimicrobials. The increasing difficulty to develop new effective antibiotics have discouraged investment in this area
and only a few new antibiotics are currently under development. An approach to overcome antibiotic resistance
could be based on antimicrobial peptides since they offer advantages over currently used microbicides.
Methods: The antimicrobial activity of the synthetic peptide AMP2041 was evaluated against 49 P. aeruginosa clinical
strains with high levels of antimicrobial resistance, isolated from humans (n = 19) and animals (n = 30). In vitro activity
was evaluated by a microdilution assay for lethal dose 90% (LD90), while the activity over time was performed by
time-kill assay with 12.5 μg/ml of AMP2014. Evidences for a direct membrane damage were investigated on P. aeruginosa
ATCC 27853 reference strain, on animal isolate PA-VET 38 and on human isolate PA-H 24 by propidium iodide and
on P. aeruginosa ATCC 27853 by scanning electron microscopy.
Results: AMP2041 showed a dose-dependent activity, with a mean (SEM) LD90 of 1.69 and 3.3 μg/ml for animal
and human strains, respectively. AMP2041 showed microbicidal activity on P. aeruginosa isolates from a patient with
cystic fibrosis (CF) and resistance increased from first infection isolate (LD90 = 0.3 μg/ml) to the mucoid phenotype
(LD90 = 10.4 μg/ml). The time-kill assay showed a time-dependent bactericidal effect of AMP2041 and LD90 was
reached within 20 min for all the strains. The stain-dead assay showed an increasing of membrane permeabilization and
SEM analysis revealed holes, dents and bursts throughout bacterial cell wall after 30 min of incubation with AMP2041.
Conclusions: The obtained results assessed for the first time the good antimicrobial activity of AMP2041 on P. aeruginosa
strains of human origin, including those deriving from a CF patient. We confirmed the excellent antimicrobial
activity of AMP2041 on P. aeruginosa strains derived from dog otitis. We also assessed that AMP2041 antimicrobial activity
is linked to changes of the P. aeruginosa cell wall morphology and to the increasing of membrane permeability
Decomposition of organic residues in soil: experimental technique and spectroscopic approach Organic Geochemistry,33.2002,327-345
No full textDRIFT (diffuse reflectance infrared Fourier-transform) spectroscopy was used to follow the early transformations that take place after the incorporation of organic materials in soil. Alfalfa (A), dried maize (DM), laboratory-composted maize (CM), and two commercial composts (YWC and MWC) confined into fiberglass bags were incubated in sand with and without planting with lettuce. DRIFT spectra of these materials before and after incubations were correlated with CO 2-C evolution and mass, carbon and nitrogen balances. Spectra obtained by successive subtractions allowed us to distinguish between the main classes of biochemical compounds (cellulose, lignin, polypeptides, pectins) and to study their degradation during incubation. Quantitative spectroscopic determination of lignin showed a relative enrichment in the incubated materials. This experimental approach can be applied to studies on the degradation pathway of green manure materials like A, DM and CM but seems less appropriate for commercial composts
Preliminary data on the efficacy of multi-wave (multi-wavelength) diode laser on bacteria in superficial canine pyoderma.
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