1,721,250 research outputs found
Visual abstract - Supplemental material for Emergency Endovascular Total Arch Exclusion With an Off-the-Shelf Bimodular Device
No full textSupplemental material, sj-pptx-1-inv-10.1177_15569845211050388 for Emergency Endovascular Total Arch Exclusion With an Off-the-Shelf Bimodular Device by Giorgia Cibin, Augusto D'Onofrio, Michele Antonello, Piero Battocchio and Gino Gerosa in Innovations</p
Visual Abstract - Supplemental material for Transapical Antegrade Ascending Aorta Stent-Grafting: Going Through the Front Door
No full textSupplemental material, Visual Abstract, for Transapical Antegrade Ascending Aorta Stent-Grafting: Going Through the Front Door by Augusto D’Onofrio, Giorgia Cibin, Michele Antonello, Raphael Caraffa, Franco Grego and Gino Gerosa in Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery</p
COVID-19: An International Perspective
No full textFilmed March 18, 2020, Brian Mitzman, Assistant Professor of Cardiothoracic Surgery at NYU Langone Health, moderates a discussion on the COVID-19 pandemic with an international group of physicians currently on the front lines. He is joined by Alan Sihoe, Honorary Consultant in Cardiothoracic Surgery at the Gleneagles Hong Kong Hospital in China; Aaron Cheng, Associate Professor of Cardiothoracic Surgery at the University of Washington; Jenelle Badulak, Assistant Professor in the Department of Pulmonary, Critical Care, and Sleep Medicine at the University of Washington; and Gino Gerosa, Chief of Cardiac Surgery at the University of Padova in Italy
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Marginal donors and organ shortness: concomitant surgical procedures during heart transplantation: a literature review
No full textHeart transplantation represents the gold standard for end-stage heart failure. However, due to the increasing demand and the shortage of available organs, donor supply remains the main limitation. Marginal donor hearts in high-risk candidates who do not meet standard listing criteria are the only alternative when life expectancy is limited, but their use is still debated. Surgical correction of detected coronary lesions or valvular heart defects allows further enlargement of the number of available organs. In this article, we offer a literature review on this topic and report two marginal donor hearts with angiography evidence of coronary stenosis and preserved ventricular function, which underwent concomitant myocardial revascularization during heart implantation
Cutting-Edge Regenerative Medicine Technologies for the Treatment of Heart Valve Calcification (Chapter 9)
Full text linkhttp://Laura Iop and Gino Gerosa (2013). Cutting-Edge Regenerative Medicine Technologies for the Treatment of Heart Valve Calcification, Calcific Aortic Valve Disease, Dr. Elena Aikawa (Ed.), ISBN: 978-953-51-1150-4, InTech, DOI: 10.5772/55327. Available from: http://www.intechopen.com/books/calcific-aortic-valve-disease/cutting-edge-regenerative-medicine-technologies-for-the-treatment-of-heart-valve-calcificatio
EFFECTS OF INSIDE-OUT SUBMITOCHONDRIAL PARTICLES (IO-SMPS) ON MITOCHONDRIA ISOLATED FROM A PORCINE EX VIVO MODEL OF DONATION AFTER CARDIOCIRCULATORY DEATH (DCD) HEART
No full textWhen it comes to heart transplantation, donation after brain death (DBD) has become the standard of
care as this method is supported by many advantages, mainly due to the possibility to easily assess
donor heart function before retrieval and sensibly shorten the detrimental period of warm ischemia.
Lately, however, the ever-increasing number of patients in waitlist for heart transplantation has
pushed the interest of researchers to find new methods to increase the donor pool [1], including heart
donation after cardiocirculatory death (DCD). The latter, nonetheless, shows several disadvantages
including a longer period of warm ischemia, long-term outcomes uncertainty, and lack of
standardized reliable biomarkers and physiological parameters predictive of function and
transplantability of DCD hearts [2]. One of the earliest cardiomyocytes degenerations starting after
cardiac death is borne by mitochondria that are involved in some distinct types of cell death.
Therefore, studying such events may help better understanding the physiological processes
underlying DCD heart transplantability, eventually leading to definition of useful biomarkers. To
achieve this, the focus of this work was the F1Fo-ATPase complex, considered as the leading candidate
responsible for the opening of a channel though the inner membrane called mitochondrial
permeability transition pore (mPTP) when the natural cofactor (Mg2+) is replaced with the physio-
pathological cofactor (Ca2+) [3]. Specifically, trying to preserve mitochondrial bioener getics and
integrity, we assessed the efficacy of IO-SMPs (inside-out submitochondrial particles) obtained by
swine hearts isolated by stepwise centrifugation from mitochondria [4], on an ex-vivo porcine model
of DCD heart (20 min of no touch after cardiac arrest followed by 2h of warm ischemia). We
evaluated the effect of IO-SMPs on Oxidative Phosphorylation and their influence on mitochondria
calcium retention capacity (CRC), an indirect index of mPTP opening, as already highlighted in other
studies. Studies are currently ongoing, but the preliminary results show that IO-SMPs are capable of
delaying the mPTP opening when swine heart mitochondria are exposed to Ca2+. Overall, this study
represents a first step towards an in-depth characterization of the physiological process activated by
a prolonged warm ischemia within mitochondria, and investigates the potential beneficial effects of
IO-SMPs, that may be applicable to all DCD solid organ
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