11,162 research outputs found
Using Ginger Extract for Synthesis of Metallic Nanoparticles and their Applications in Water Treatment
No full textThe chemical and physical methods for nanoparticle production are relatively expensive and complicated, let alone their toxicity for the ecosystem. On the contrary, using ginger to reduce metal ions into nanoparticles is a more easier and rapid technique, as ginger contains reducing agents; e.g., alkaloids, and phenolic compounds. We synthesized Silver, Copper and Nickel nanoparticles using ginger extract and characterized them by Transmission Electron micrograph, X-ray diffraction, and UV-Vis spectrophotometer. Different concentrations of Silver, Copper and Nickel nanoparticles (100, 200, 300, 400,500 mg/ml) were tested on some chemicals and the microbial content of two water samples [(Brackish lake (Mariout), El Kilo 21 lake)] Alexandria. We concluded that the addition of 100 μl of copper, 50 μl of silver, and 150 μl of Nickel nanoparticles / 50 ml of the water sample removed the total content of nitrate and phosphate efficiently, whereas 30 μl of copper, 30 μl of silver and 75 μl of Nickel nanoparticle / 50 ml of the water sample totally inhibited bacterial contamination. This demonstrates that the preparation of Silver, Copper and Nickel nanoparticles using ginger extract is a safe, easy and economic technique, in addition to being effective in water decontamination and environmental applications
Identification of serotonin 5-HT1A receptor partial agonists in ginger
No full textAnimal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the human serotonin 5-HT(1A) receptor with significant to moderate binding affinities (K(i)=3-20 microM). [(35)S]-GTP gamma S assays indicated that 10-shogaol, 1-dehydro-6-gingerdione, and particularly the whole lipophilic ginger extract (K(i)=11.6 microg/ml) partially activate the 5-HT(1A) receptor (20-60% of maximal activation). In addition, the intestinal absorption of gingerols and shogaols was simulated and their interactions with P-glycoprotein were measured, suggesting a favourable pharmacokinetic profile for the 5-HT(1A) active compounds
Ginger Extract Inhibits T2 Bacteriophage Yield in E. coli
No full textExtracts of ginger inhibit the growth of bacteria and viruses of animal cells. An extract of ginger was prepared with alcohol and LB broth. At concentrations of 1, 2, 4, and 6 ml of ginger extract per 100 ml of LB broth, there was very little effect on the replication of E. coli. At concentrations of 2, 4, and 6 ml of ginger extract per 100 ml of LB broth, the yield of T2 bacteriophage decreased by 22% to 28%. The longer ginger extract was in contact with the bacterial cells prior to infection, the larger was the inhibition of T2 bacteriophage yield. When added 50 minutes before infection, the yield of T2 bacteriophage was 93.75% of the control, at 100 minutes prior to infection, the yield was 87.05% of the control and at 150 minutes prior to infection, the yield was 79.91% of the control. The addition of excess glutamine partially reversed the inhibition of T2 yield by ginger extract. With 2 ml of ginger extract, the yield of T2 bacteriophage was 71.3% of the control. With ginger extract and 30 mM glutamine, the yield was 81.4% of the control and with 45 mM glutamine, the yield was 93.0% of the control. With ginger extract plus 1 mM, 3 mM, and 5 mM nucleosides, the yield was 29.85%, 106.1%, and 103.0% of the control. These results suggest that ginger extract inhibits the replication of T2 bacteriophage by inhibiting the metabolism of glutamine and the synthesis of nucleotides during T2 replication
Chemopreventive Efficacy of Ginger Extract (Zingiber officinale)
No full textThe liver cells were cultured in the presence of ginger extract at various concentrations (0-1 mg /ml) for 24 h and the cells viability and proliferation rate were evaluated by MTS and BrdU assays, while apoptosis was evaluated by colorimetric determination of caspase 8 and 3 activities. Ginger extract exhibited a dose dependent inhibition of viability and proliferation of WRL-68, HLE and HepG2 cells with IC50 of 569.69 ± 7.99 µg/ml, 389.71 ± 26.56 µg/ml and 358.71 ± 17.12 µg/ml respectively. Ginger extract induced apoptosis through activation of caspase-8 and 3 in a dose dependent pattern for all cells at concentration ranging from 0-500 mg/ml. We found that antiproliferative effect of ginger extract could be associated with induction of apoptosis as shown by increased activities of caspase 8 and 3.The results from this study suggest that ginger extract has chemopreventive properties against hepatoma cells HepG2 and HLE by inhibiting cellular proliferation and inducing apoptosis.Keywords : antiproliferation, apoptosis, caspases, Zingiber officinale</jats:p
Metadata Representations for Queryable ML Model Zoos
No full textMachine learning (ML) practitioners and organizations are building model zoos of pre-trained models, containing metadata describing properties of the ML models and datasets that are useful for reporting, auditing, reproducibility, and interpretability purposes. The metatada is currently not standardised; its expressivity is limited; and there is no interoperable way to store and query it. Consequently, model search, reuse, comparison, and composition are hindered. In this paper, we advocate for standardized ML model metadata representation and management, proposing a toolkit supported to help practitioners manage and query that metadata.Web Information SystemsHuman-Centred Artificial Intelligenc
A Manifesto of Nodalism
No full textThis paper proposes the notion of Nodalism as a means describing contemporary culture and of understanding my own creative practice in electronic music composition. It draws on theories and ideas from Kirby, Bauman, Bourriaud, Deleuze, Guatarri, and Gochenour, to demonstrate how networks of ideas or connectionist neural models of cognitive behaviour can be used to contextualize, understand and become a creative tool for the creation of contemporary electronic music
Microencapsulation of ginger (Zingiber officinale) extract by spray drying technology
No full textThe aim of this study was to evaluate the effect of microencapsulation of ginger (Zingiber officinale Roscoe) extract using maltodextrin (MD) and/or gum arabic (GA) as microencapsulation agents on its 6-gingerol content, total phenolic and antioxidant activity. Four slurries containing 95 mL/100 mL of ginger extract (2 g solids/100 mL) and 5 g/100 mL of a blend of maltodextrin:gum arabic of weight ratios (4:1, 1:4, 5:0, and 0:5 g:g) were prepared and they were separately spray dried at 160 °C inlet air temperature to produce ginger extract powders. Ginger extract contained 20.6 ± 0.2 (mg/g solids) 6-gingerol, 7.7 ± 0.6 (mg/g solids) gallic acid equivalents and had an antioxidant activity of 19.9 ± 0.8 (μmol Trolox/g solids). Microencapsulation resulted in a decline in the quantity of 6-gingerol present in ginger extract regardless of the maltodextrin and gum arabic blend. Microencapsulation of ginger extract also reduced gallic acid equivalents and antioxidant activity. Ginger extract dried with maltodextrin:gum arabic (1:4 g:g) and (0:5 g:g) had larger particle size than that dried with maltodextrin:gum arabic (4:1 g:g) and (5:0 g:g). Maltodextrin:gum arabic (4:1 g:g) and (5:0 g:g) had better morphological properties than maltodextrin:gum arabic (4:1 g:g) and (5:0 g:g). Microencapsulated ginger extract powder may be used as a novel food ingredient
The GINGER Project
No full textGINGER (Gyroscopes IN General Relativity) is a project aiming at measuring the Lense-Thirring effect, at 1% level, with an experiment on earth. It is based on an array of ring-lasers, which are the most sensitive inertial sensors to measure the rotation rate of the Earth. The GINGER project is still under discussion; the experiment G-GranSasso is an R&D experiment financed by INFN Group II, it is studying the key points of GINGER and at the same time developing prototypes. In the following the signal coming out of a ring-laser and the present sensitivity are described.The prototypes GP2 and GINGERino and the preliminary results are reported. This project is inter-disciplinary since ring-lasers provide informations for the fast variation of the earth rotation rate, they are used for the rotational seismology and for top sensitivity angle metrology
Characterization of Algerian turmeric and ginger based on their physicochemical, functional and biological properties: Characterisation of Algerian turmeric and ginger
No full textThe purpose of the study was to characterize (physicochemical properties, functional properties, antioxidant contents and biological activities) of two Algerian spices, turmeric and ginger. The results showed the richness of both spices in phytochemicals especially in polyphenols. Compared to ginger, which showed greater affinity for oil, turmeric powder had more affinity for water. In addition, turmeric swelled more (14.17 ml g-1) than ginger powder (8.33 ml g-1). The methanolic extract showed the highest total antioxidant activities of 470.72 ± 3.13 and 228.73 ± 42.19 AAE 100 g-1 for turmeric and ginger respectively. The aqueous extracts didn’t show anticoagulant activity while, the methanolic and acetonic extracts showed anticoagulant activity in a dose – dependent manner. As the butanolic extracts prevented the blood clot from forming, it could be used for medical application in future. Therefore, turmeric and ginger are a rich source of bioactive molecules and have functional and biological properties to be exploited in the food and pharmaceutical industry
Aktivitas antimikroba ekstrak jahe (Zingiber officinale Roscoe) terhadap beberapa bakteri patogen
No full texthazards to the human health. Ginger (Zingiber officinale Roscoe) is commonly used as traditional medicine. It has a potential as antimicrobial agent by inhibit or kill microbes in dose dependent manner. The principle compounds of ginger are essential oils and non volatile compounds which maximum have antimicrobial activity. The objectives of this research are: (1) to study the yield of ginger extracts by multistage maceration with different polarity solvents, (2) to study antimicrobial activity of hexane, ethyl acetate and ethanol extract of ginger against foodborne pathogen such as Staphylococcus aureus, Bacillus cereus and Salmonella enterica serovar Typhimurium. Ginger extracts were prepared by multistage maceration method using solvent hexane, ethyl acetate and ethanol. The ginger extracts were assayed for antimicrobial activity by agar well diffusion method with Diameter Inhibition Zone (DIZ) and dillution broth method. The yield of hexane, ethyl acetate and ethanol ginger extracts from multistage maceration were respectively 3,57; 3,17; 3,02 g/100 g dry ginger. The DIZ value for Staphylococcus aureus were 5,0; 5,7; 1,3 mm with hexane, ethyl acetate and ethanol ginger extracts respectively 6,1; 6,6; 6,0 mm for Bacillus cereus and Salmonella Typhimurium were show no inhibitory zone. This results showed that the ginger extracts from multistage maceration have a weak antimicrobial activity (1,3 – 6,6 mm) against Gram-positive bacterial. The inhibition activity was determined for ethyl acetate ginger extract that showed the relatively highest inhibition zone. The minimum inhibition concentration did not reach in a range concentration between 5 – 20 mg/ml against Staphylococcus aureus and Bacillus cereus, therefore ginger extracts from multistage maceration with rotavapor temperature 50 o C and freeze dry process were not efficient to developed as natural antimicrobial
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