2,531 research outputs found

    Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.

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    Testicular germ cell tumor (TGCT) is the most common cancer in young men and is notable for its high familial risks. So far, six loci associated with TGCT have been reported. From genome-wide association study (GWAS) analysis of 307,291 SNPs in 986 TGCT cases and 4,946 controls, we selected for follow-up 694 SNPs, which we genotyped in a further 1,064 TGCT cases and 10,082 controls from the UK. We identified SNPs at nine new loci (1q22, 1q24.1, 3p24.3, 4q24, 5q31.1, 8q13.3, 16q12.1, 17q22 and 21q22.3) showing association with TGCT (P < 5 × 10(-8)), which together account for an additional 4-6% of the familial risk of TGCT. The loci include genes plausibly related to TGCT development. PRDM14, at 8q13.3, is essential for early germ cell specification, and DAZL, at 3p24.3, is required for the regulation of germ cell development. Furthermore, PITX1, at 5q31.1, regulates TERT expression and is the third TGCT-associated locus implicated in telomerase regulation

    50-Gb/s Direct Conversion QPSK Modulator and Demodulator MMICs for Terahertz Communications at 300 GHz

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    We demonstrate direct quadrature modulator and demodulator monolithic microwave integrated circuits for future terahertz communications at 300 GHz based on the quadrature phase-shift keying (QPSK) modulation format. For the modulating and demodulating signal, we employed half-Gilbert cell mixers, which provide balanced signaling and moderate performance in conversion efficiency with a simple circuit configuration. In order to maintain the balance performance of the modulator and demodulator, passive baluns and couplers are implemented with thin-film microstrip lines, which exhibit less insertion loss than inverted microstrip lines (IMSLs), while the active mixers are based on IMSLs for short interconnections. The half-Gilbert-cell mixers have a wide enough operation bandwidth for high-throughput communications of more than 10% at 300 GHz. According to the static constellation of the modulator, imbalance is expected to be less than approximately +/- 0.6 dB angle 4 degrees. A nonchip back-to-back experiment was conducted at up to 60 Gb/s, and 50-Gb/s operation was verified with a low bit error rate on the order of 10(-8) or less. The results demonstrate that the QPSK modulation scheme can be applied to double the data rate at terahertz frequencies.115247sciescopu

    EVALUATION ON CONSISTENCY BETWEEN HJ-1 CCD AND TM IMAGES IN MONITORING FRACTIONAL GREEN VEGETATION COVER

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    The fractional green vegetation cover (Fc) is an important climate model parameter. Remote sensing technique has become one of the most effective means to acquire vegetation dynamics information. The CCD cameras onboard HJ-1 satellites (Environment and Disaster monitoring and forecasting Satellite constellation) are advanced in revisit frequency and image coverage compared with Landsat TM. This study aims to assess the capability of HJ-1 CCD images in monitoring of Fc in terms of comparing with the widely used TM images. The quality of HJ-1 CCD is compared with the same temporal TM image in two aspects: the image statistical analysis and the image application analysis. After the comparison between the HJ-1 CCD image and TM image of the same area. The results show a high level of uniform between HJ-1 and TM images. Therefore, the conclusion may be drawn that the HJ-1 CCD image is feasible and suitable for Fc monitoring.Engineering, Electrical &amp; ElectronicGeosciences, MultidisciplinaryRemote SensingEICPCI-S(ISTP)

    Konsep Pendidikan Untuk Perempuan Perspektif Nyai Hj. Masriyah Amva

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    One figure of a well-known female cleric in Cirebon is Nyai Hj. Masriyah Amva. He is a female ulama figure who is different from the others, Nyai Hj. Masriyah Amva became the caretaker of Kebon Jambu Al-Islamy Islamic Boarding School in Babakan Village, Ciwaringin Cirebon, where she became the leader of more than 1,000 male and female santri. The author presents this paper in the form of a qualitative approach, with qualitative descriptive methods, collection techniques using interview and observation methods, which are then analyzed by interactive analysis techniques namely data reduction, data presentation and drawing conclusions. This study aims to illustrate the Concept of Education for Perpective Women Nyai Hj. Masriyah Amva at Kebon Jambu Al-Islamy Islamic Boarding School. According to him, education for women consists of material elements, immaterial elements and character elements. The material element is education that equips students with various sciences according to their respective levels, while the immaterial element is that women are able to present and involve the Creator in all their life processes, according to Nyai Hj. Masriyah Amva, that is, women must be educated in such a way as to form a woman who is persistent, independent, has a personality, is pious and tough with hard prayers, hard efforts and always has positive thoughts.Salah satu sosok ulama perempuan yang sangat dikenal di Cirebon adalah Nyai Hj. Masriyah Amva. Beliau adalah sosok ulama perempuan yang berbeda dengan lainnya, Nyai Hj. Masriyah Amva menjadi pengasuh Pondok Pesantren Kebon Jambu Al-Islamy di Desa Babakan, Ciwaringin Cirebon, beliau menjadi pemimpin lebih dari 1.000 santri laki-laki dan perempuan. Penulis menyajikan tulisan ini dalam bentuk pendekatan kualitatif, dengan metode deskriptif kualitatif, teknik pengumpulan menggunakan metode wawancara dan observasi, yang kemudian dianalisis dengan teknik analisis interaktif yaitu reduksi data, penyajian data dan penarikan kesimpulan. Penelitian ini bertujuan untuk menggambarkan Konsep Pendidikan untuk Perempuan Perpektif Nyai Hj. Masriyah Amva di Pondok Pesantren Kebon Jambu Al-Islamy. Menurutya pendidikan untuk perempuan adanya unsur material, unsur imaterial dan unsur karakter. Unsur material adalah pendidikan yang membekali santrinya dengan berbagai ilmu pengetahuan sesuai jenjangnya masing-masing, sedangkan unsur Imaterial adalah para perempuan mampu menghadirkan dan melibatkan Sang Pencipta dalam semua proses kehidupannya, unsur karakter menurut Nyai Hj. Masriyah Amva yaitu perempuan harus dididik sedemikian rupa hingga terbentuklah sosok perempuan yang gigih, mandiri, berkepribadian, bertaqwa dan tangguh dengan do`a keras, usaha keras dan selalu berfikiran positif

    A Business Model Analysis On Hj Nina’s Rental Housing Using Business Model Canvas Approach

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    Tangerang City has great potential for the growth of residential property projects. This region called thriving city due to economic growth which Tangerang City quite significantly from National. Terms of geographical, Tangerang City have access to strategic Jakarta so many transportation infrastructure could trigger growth property in the area. With the existence of business opportunities related to housing in Tangerang City, Mrs Hj Nina take advantage of these business opportunities by building land owned by property for a rented houses. But in running her business, Mrs Hj Nina has the main obstacle is competition around rented houses. One of the ways that Mrs Hj Nina’s rented house can explore the existing potential is by analyzing the right business model. Based on the results of the research on the identification of business model elements that exist in the house of Mrs Hj Nina, the author proposes several improvement programs for Mrs Hj Nina, namely expanding the house rent, develop business rented by diversifying business, adding facilities, doing community service, the owner having face to face meetings with rented houses, and house renters are active in the activities of local residents. With proposal the program for the improvement is expected to makes a business Mrs Hj Nina can develop and survived in the field of the business

    VALIDATION FOR THE ABSOLUTE RADIOMETRIC CALIBRATION OF THE HJ-1B CCD SENSORS OF CHINA

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    On September 6, 2008, the satellite HJ-1B was launched into a sun-synchronous, near-polar orbit. In order to determine temporal changes of the absolute radiometric calibration of the HJ-1B satellite in flight, a program was carried out at DunHuang calibration field, Gansu province of China, from August 19 to 30, 2009. In this work, reflectance -based calibration method was employed to simulate the absolute calibration coefficients of the HJ-1B CCD sensors. Then the cotton field, cement court, water pool and test site was selected to validate the calibration coefficient. The validation results indicated that there had a good agreement between the imaged-based reflectance and the ground measurement of the type of cement court and test site. On the other hand, there had a disagreement of the type of cotton field and water because of the effect of mixed pixel.Geosciences, MultidisciplinaryRemote SensingEICPCI-S(ISTP)

    Treatment for congenital toxoplasmosis: finding out what works

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    Evidence for the effectiveness of prenatal or postnatal treatment for congenital toxoplasmosis will be critical to guide policy about prenatal and neonatal screening over the next 10 years, let alone the next 100. Randomised controlled trials are needed to address questions about treatment effectiveness, although cohort studies are also needed to provide information on prognosis, especially disability. Nowhere are such studies needed more than in South America where congenital toxoplasmosis is a major public health problem

    KERUGIAN YANG DIDERITA OLEH DOKTER AKIBAT PENGELOLAAN DANA BADAN PENYELENGGARA JAMINAN SOSIAL KESEHATAN DI RUMAH SAKIT UMUM DAERAH HJ. ANNA LASMANAH BANJARNEGARA

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    Research with the title Losses Suffered by Doctors due to the Management of “Badan Penyelenggara Jaminan Sosial Kesehatan” in the Hj. Anna Lasmanah Hospital Banjarnegara was used based on the statement of the Hj. Anna Lasmanah Hospital’s Director in 2018, dr. Agung Budianto. Research that have been done by the author in order to find out the truth of the data about the loss that experienced by doctors using normative methods through interviews between the author and Hj. Anna Lasmanah Hospital’s Director as well as several representatives of doctors or dentists and this interview also involve the Head of “BPJS Kesehatan” Banjarnegara field office. The result of this research is the loss that experienced by the doctors is not material losses but immaterial losses. This immaterial losses is the disappointment of the doctors with “BPJS Kesehatan” who did the late payments which make the economic needed of doctors not being able to get on time

    MONITORING OF DEGRADING GRASSLAND BASED ON HJ-1A-HSI IMAGE

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    Grassland is one of the most important parts of ecosystem on the earth. In China, one of the best grass lands is degrading because of draught or effects of human activity. It is important to monitor the growing condition of degrading grasslands. LAI is an important variable which can accurately represent the growing situation of grass. With DSD method, hyper-spectral images from HJ-1A satellite are used to inverse LAI accurately by restraining the effect of background. In this paper, multi spectral image was used to retrieve LAI with BRDF method for comparing. The maps of LAI and degradation level in study area were made. According to the results, the DSD method can retrieve LAI of grassland accurately and the HSI image of HJ-1A is a potential ideal data source for monitoring grassland.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345638900196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Engineering, Electrical &amp; ElectronicGeosciences, MultidisciplinaryRemote SensingCPCI-S(ISTP)

    PENYULUHAN PENGHITUNGAN BREAK EVEN POINT PADA USAHA KERUPUK KEMPLANG & PEMPEK Hj. EVA YUNUS PALEMBANG

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    The dedication to this community is entitled Counseling on Break Even Point (BEP) Analysis in the Kerupuk Kemplang and Pempek Hj Eva Yunus Business in Palembang City, located on Jl KH. A. Azhari Lorong Anten-anten no. 576 RT. 16 RW.04 Kelurahan 5 Ulu Palembang is under the auspices of PT Pusri Palembang. This business is a family business (home industry) and since 1990 this business has been held by Hj Eva Yunus. Previously this business belonged to Hj Eva Yunus's parents. Since 2012 development has been carried out with additional products namely; pempek, model or tekwan, previously only kerupuk and kemplang only. Based on problems related to the calculation of Break Even Point (BEP) in the Kerupuk Kemplang and Pempek Business Hj Eva Yunus in Palembang City, and how to calculate the Break Even Point (BEP) in the Kerupuk Kemplang and Pempek Business, and how many units that must be generated so that the company earns a profit which is expected. In this effort, the author sees that there are not 5 direct workers and 5 indirect workers. The initial capital of Rp. 500,000.00 (in 1990) after the development of this business was fostered by PT Pusri. They get a loan of IDR 50,000,000 - IDR 70,000,000 per 2 years with an interest of 3%. In this business, the business owner is not counted as labor and the building where the business is located is not counted, nor are his nephews or workers working in the house. So by giving a BEP Analysis counseling, it is expected that business owners can calculate the BEP in units and the BEP in rupiah can also determine the expected profit
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