1,721,076 research outputs found
Recommended from our members
Personal Narratives and Accounts
No full textRecording of Ghulam Haider reciting a historical narrative in the Hunza dialect of Burushaski
Recommended from our members
Personal Narratives and Accounts
No full textRecording of Ghulam Haider reciting a traditional narrative in the Hunza dialect of Burushaski
Recommended from our members
Personal Narratives and Accounts
No full textRecording of Ghulam Haider reciting a historical narrative on the Silk Road in the Hunza dialect of Burushaski
Correlation between Standardized Uptake Values and Ki-67 in Different Cancers
Full text linkTitle:
Correlation between Standardized Uptake Values and Ki-67 on PET Scan in Different Cancers
Introduction:
Cancer is a leading cause of morbidity and mortality worldwide. Accurate assessment of tumor aggressiveness is crucial for prognosis and treatment planning. Two widely used markers are Ki-67, a nuclear protein indicating cellular proliferation, and Standardized Uptake Value (SUV) derived from FDG-PET scans, which reflects tumor metabolic activity. This study aims to evaluate the correlation between SUV and Ki-67 across different cancers to determine whether SUV can serve as a non-invasive surrogate marker for tumor proliferation.
Objectives:
• To determine the correlation between SUV on PET scan and Ki-67 expression in different types of cancers.
• To assess whether SUV can predict tumor proliferative index (Ki-67).
• To explore the influence of demographic variables such as age and gender on SUV and Ki-67 correlation.
Methodology:
A cross-sectional study was conducted at Jinnah Postgraduate Medical Center, Karachi, from [Oct 2024 to march 2025]. A total of 94 patients with histologically confirmed malignancies who underwent FDG-PET scans and Ki-67 immunohistochemistry were included. Patients who had received prior chemotherapy or radiotherapy were excluded. Data on age, gender, SUV (max), and Ki-67 index were collected. Correlation and regression analyses were performed using SPSS version 25.
Results:
A statistically significant positive correlation was found between SUV and Ki-67 index (p < 0.05), with the strongest association observed in breast Cancer, lung cancer, B Cell lymphoma. Multivariate regression revealed that Ki-67 and age significantly predicted SUV values. Female patients, particularly those with breast cancer, showed a stronger SUV–Ki-67 correlation compared to males.
Conclusion:
SUV on PET scan shows a significant correlation with Ki-67 index, suggesting its potential as a non-invasive marker of tumor proliferation. Incorporating SUV into clinica
Assessing MSI Status in GI Cancers (Rectal, Gastric, and Colon Cancer): A Cross-Sectional Study
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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