1,720,955 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
State-of-the-art REDOR and TEDOR methods for elucidation of protein structure and interactions
Get PDFProtein structure determination is vital for elucidating their function, folding or misfolding pathways, and their interaction with other biomolecules, small molecules and membranes. In the field of neurodegenerative disorders like Parkinson’s Disease and Alzheimer’s Disease, amyloid fibrils that constitute the aggregates in the diseased brain are formed due to misfolding of proteins like a-synuclein (a-syn) and amyloid-b. Understanding the structure of these amyloid fibrils will be beneficial for probing amyloid- ligand interactions, amyloid-membrane interactions and even their misfolding pathways. This dissertation thesis introduces some state-of-the-art solid-state nuclear magnetic resonance (SSNMR) techniques to investigate protein structures and their interactions, which will facilitate the study of amyloid fibrils formed in the neurodegenerative disorders.
One of the major biophysical techniques to probe biomolecular structure and their interactions is magic angle spinning (MAS) SSNMR spectroscopy due to its ability to examine insoluble systems and with no inherent restriction on the size of the molecule. For structure determination and refinement, we employ famous and robust techniques like rotational echo double resonance (REDOR) and transferred echo double resonance (TEDOR) that recouples the dipolar couplings between two selective heteronuclear spins present in the biomolecule. The dipolar coupling is directly proportional to the gyromagnetic ratio (g) of the spins and indirectly proportional to the cube of the distance between them. Hence, fitting the dipolar dephasing curves to Bessel function of first kind provide us quantitative, precise and unambiguous distance restraints within or between molecules and these distance restraints will assist the structure calculations or docking of small molecules or other biomolecules to the proteins.
Structure or ligand binding mode determination with REDOR or TEDOR has been performed extensively on all types of biomolecules, small molecules and inorganic compounds in the past couple of decades. However, due to utilization of lower g nuclei in the spin pair and restrictions in the pulse sequence, the sensitivity, resolution, the distance detection range, and the types of sample on which REDOR and TEDOR can be applied have been limited. In my thesis, I have focused on advancing REDOR and TEDOR methodology such that we can obtain quantitative and precise distances up to 1.5-2 nm. These are the longest quantitative distances obtained by SSNMR so far. This has been made possible by utilizing high g spins, like 1H and 19F as REDOR or TEDOR spins. The novel methods are multidimensional in nature, can be applied to uniformly 13C or 2H labeled proteins, highly sensitive and will be performed in reduced experimental time due to 1H-detection.
1H-detection is feasible under fast MAS and in perdeuterated proteins. Perdeuteration of protein leads to enhanced 1H spin-spin relaxation time (T2), which is a huge advantage for performing REDOR dephasing or TEDOR build-up for longer times and hence increasing the distance detection range. The REDOR or TEDOR techniques introduced in this thesis have been mainly applied on uniformly-13C, 2H, 15N (U-CDN) labeled proteins, like GB1 crystalline protein and a-syn fibrils and their mutants, back-exchanged to 10-30% 1H. 1H-detected REDOR or TEDOR techniques developed here are unique in measuring distances between the side chain 13C atoms and backbone 1H atoms in the proteins, thereby providing accurate restraints for side chain orientations and not only backbone restraints.
Performing REDOR with 19F atom is advantageous because of the usefulness and popularity of 19F atom in the drug or diagnostic agent development industry. In our studies, we have also successfully demonstrated the incorporation of 19F atom in a-syn fibrils through mutagenesis and chemical modification. Thereafter, we performed 13C-19F REDOR to obtain distances of up to 10 Å and with our newly developed 1H-detected REDOR pulse sequence, we obtained 1H-19F unambiguous REDOR distances of up to 17 Å in a-syn fibrils. Taken together, this thesis lays a foundation towards shaping REDOR and TEDOR spectroscopy to be feasible for — (1) structure determination and refinement of uniformly 13C labeled and perdeuterated proteins, and (2) binding mode determination of fluorinated imaging agents or drugs, and lipid membranes to amyloid fibrils like a-syn, or non-fluorinated small molecules to 19F- labeled proteins.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-08-01The student, Manali Ghosh, accepted the attached license on 2019-06-17 at 19:31.The student, Manali Ghosh, submitted this Dissertation for approval on 2019-06-17 at 19:41.This Dissertation was approved for publication on 2019-06-18 at 12:41.DSpace SAF Submission Ingestion Package generated from Vireo submission #14051 on 2019-11-26 at 13:03:32Made available in DSpace on 2019-11-26T20:49:14Z (GMT). No. of bitstreams: 2
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Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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