1,720,986 research outputs found
Highlights From 2017: Impactful Topics Published in the Annals of Nuclear Medicine
The aim of the review is to highlight articles published in 2017 in the Annals of Nuclear Medicine, an official peer-reviewed journal of the Japanese Society of Nuclear Medicine. Among all published manuscripts during the past year, we conducted a subjective selection of the most relevant topics. Fourteen fascinating articles are included in this review, ranging in topic from preclinical to clinical arenas
Optimization of Precursor Preparation in PSMA-11 Radiolabeling to Obtain a Highly Reproducible Radiochemical Yield
[68Ga]Ga-PSMA-11 PET/CT plays a pivotal role in the diagnosis and staging of prostate cancer because of its higher sensitivity and detection rate compared with traditional choline PET/CT. A highly reproducible radiochemical yield of the radiopharmaceutical to be used in the clinical routine is an important parameter for planning and optimization of clinical activity. During radiometallation of PSMA-11, the presence of metal ion contaminants in the peptide precursor may cause a decrease in the [68Ga]Ga-PSMA-11 radiochemical yield because of metal ion contaminants competition with gallium-68. To optimize the radiochemical yield of [68Ga]Ga-PSMA-11 radiosynthesis, data obtained by preparing the solution of the PSMA-11 precursor with three different methods (A, B, and C) were compared. Methods A and B consisted of the reconstitution of different quantities of precursor (1000 μg and 30 μg, respectively) to obtain a 1 μg/mL solution. In Method A, the precursor solution was aliquoted and stored frozen, while the precursor solution obtained with Method B was entirely used. Method C consisted of the reconstitution of 1000 μg of precursor taking into account net peptide content as described in European Pharmacopoeia. Radiosynthesis data demonstrated that reconstitution methods B and C gave a consistently higher and reproducible radiochemical yield, highlighting the role of metals and precursor storage conditions on the synthesis performance
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Il rilievo topografico
Il lavoro dà conto del rilievo topografico e della revisione dell'intera documentazione di scavo da parte dell'autore di uno scavo che, nato come scavo di emergenza nel 1989 e diventato poi scavo scuola della Scuola di Specializzazione in Archeologia dell'Università di Padova fino al 2013, ha visto impiegare diverse tipologie di rilievo topografico e di restituzione.
L'excursus attraverso queste diverse fasi (rilievo diretto ed elaborazione di planimetrie su poliestere fino al 2003, rilievo a stazione totale ed elaborazione di planimetrie in ambiente CAD dal 2004 al 2006 ed infine rilievo a Stazione Totale e fotogrammetria monoscopica ed elaborazione di planimetrie in ambiente GIS dal 2007 al 2013) diventa l'occasione per ragionare su come sia cambiato il rilievo archeologico stesso. Grossa parte del lavoro di revisione è stato poi rivolto alla trasformazione dei legacy data (sia quelli che nascevano su poliestere sia quelli digitali) secondo una struttura di shapefile che si propone come modello per la gestione di un qualsiasi scavo complesso. I problemi riscontrati nella gestione dei legacy data portano l'autore a suggerire delle operazioni in fase di digitalizzazione che possono risultare utili a chi si trovi in situazioni simili.
Da ultimo ci si dedica a una riflessione su cosa è diventato il rilievo archeologico nell'era digitale, non tanto dal punto di vista delle nuove tecnologie impiegate, quanto da quello della diversa attenzione che le nuove tecnologie permettono di dedicare alla terza dimensione, non più da considerarsi un mero attributo grafico delle planimetrie di scavo, ma vero e proprio elemento di cui rilevare la complessità
Teatri greci arcaici. Settant’anni dopo
The volume Teatri greci arcaici. Da Minosse a Pericle (1947) is the most complex and controversial scientific outcome of the research concerning Greek archaeology of Carlo Anti. Seventy years after its release we propose a rereading of the work under different aspects. First, its reception by the scholarly community of the time will be illustrated followed by an accurate listing of the archaeological investigations conducted since then. Thereby it will be observed how much the new excavations contributed to understand the origin of the architectural forms of the Greek theatre.
The paper reveals how the difficult research path undertaken by Carlo Anti received strong critiques in the first decades, that only slowly became more positive in the following years. Especially in the last 20 years theoretical researches and practical field activities have reevaluated the main ideas of the venetian scholar and have demonstrated with great evidence its absolute worth and central significance. To shed light on the outline of the theory regarding the “Greek Archaic Theaters” the recent investigations conducted in the area of the Theater of Dionysus in Athens are of particular importance since they revealed the presence of a rectilinear wooden arrangement perfectly comparable with the one imagined without any proof by Carlo Anti in 1947
- …
