1,720,958 research outputs found
Immunological Differences in Women Compared with Men: Overview and Contributing Factors
No full textCitation: Ghazeeri G, Abdullah L, Abbas O. Immunological differences in women compared with men: overview and contributing factors. Am J Reprod Immunol 2011 Gender differences in the innate and adaptive immune systems have long been observed in humans. These immunological differences in immune function manifest as diverse susceptibilities to different types of infections and varied risks of developing autoimmune disorders and maybe even, cancers. Several factors contribute to the development of this immunological dimorphism including sex hormones, genetic makeup, environmental causes, and more recently microchimerism. Although the aim behind this sexual immune dimorphism is still unclear, it is tempting to believe that the higher risk of developing autoimmune diseases in women somehow serves the higher evolutionary goal of reproduction and creating new life. © 2011 John Wiley and Sons A-S
Immunological differences in women compared with men: overview and contributing factors.
No full textCitation: Ghazeeri G, Abdullah L, Abbas O. Immunological differences in women compared with men: overview and contributing factors. Am J Reprod Immunol 2011; 66: 163-169 Gender differences in the innate and adaptive immune systems have long been observed in humans. These immunological differences in immune function manifest as diverse susceptibilities to different types of infections and varied risks of developing autoimmune disorders and maybe even, cancers. Several factors contribute to the development of this immunological dimorphism including sex hormones, genetic makeup, environmental causes, and more recently microchimerism. Although the aim behind this sexual immune dimorphism is still unclear, it is tempting to believe that the higher risk of developing autoimmune diseases in women somehow serves the higher evolutionary goal of reproduction and creating new life. © 2011 John Wiley and Sons A-S.Ackerman LS, 2006, ARCH DERMATOL, V142, P371, DOI 10.1001-archderm.142.3.371; Alter MJ, 1999, NEW ENGL J MED, V341, P556, DOI 10.1056-NEJM199908193410802; Asai K, 2001, SHOCK, V16, P340, DOI 10.1097-00024382-200116050-00003; Bouman A, 2004, AM J REPROD IMMUNOL, V52, P19, DOI 10.1111-j.1600-0897.2004.00177.x; Bouman A, 2005, HUM REPROD UPDATE, V11, P411, DOI 10.1093-humupd-dmi008; CACCIARI E, 1981, J IMMUNOGENET, V8, P337; Cutolo M, 2004, J RHEUMATOL, V31, P419; Dal H, 2008, J DERMATOL, V35, P55, DOI 10.1111-j.1346-8138.2008.00416.x; Damian DL, 2008, J INVEST DERMATOL, V128, P447, DOI 10.1038-sj.jid.5701058; Dao H, 2007, GENDER MED, V4, P308; Evans PC, 1999, BLOOD, V93, P2033; Gammill HS, 2010, INT J DEV BIOL, V54, P531, DOI 10.1387-ijdb.082767hg; Giacomoni PU, 2009, J DERMATOL SCI, V55, P144, DOI 10.1016-j.jdermsci.2009.06.001; Giltay EJ, 2000, J CLIN ENDOCR METAB, V85, P1648, DOI 10.1210-jc.85.4.1648; Gleicher N, 2007, J AUTOIMMUN, V28, P1, DOI 10.1016-j.jaut.2006.12.004; Grimaldi CM, 2005, MOL IMMUNOL, V42, P811, DOI 10.1016-j.molimm.2004.05.014; Heldring N, 2007, PHYSIOL REV, V87, P905, DOI 10.1152-physrev.00026.2006; Huber JP, 2010, J IMMUNOL, V185, P813, DOI 10.4049-jimmunol.1000469; IVARSSON SA, 1995, ACTA PAEDIATR, V84, P63, DOI 10.1111-j.1651-2227.1995.tb13485.x; Jacob CO, 2009, P NATL ACAD SCI USA, V106, P6256, DOI 10.1073-pnas.0901181106; Klein SL, 2004, PARASITE IMMUNOL, V26, P247, DOI 10.1111-j.0141-9838.2004.00710.x; Lahita RG, 2000, RHEUM DIS CLIN N AM, V26, P951, DOI 10.1016-S0889-857X(05)70178-2; Lasithiotakis K, 2008, CANCER, V112, P1795, DOI 10.1002-cncr.23359; Lockshin MD, 2010, ANN NY ACAD SCI, V1193, P22, DOI 10.1111-j.1749-6632.2009.05293.x; Medina E, 2001, J INFECT DIS, V184, P846, DOI 10.1086-323292; Naugler WE, 2007, SCIENCE, V317, P121, DOI 10.1126-science.1140485; Oliver JE, 2009, ARTHRITIS RES THER, V11, DOI 10.1186-ar2825; Olsen NJ, 1996, ENDOCR REV, V17, P369, DOI 10.1210-er.17.4.369; Orbach H, 2007, AUTOIMMUN REV, V6, P537, DOI 10.1016-j.autrev.2006.10.005; Ozbalkan Z, 2005, ARTHRITIS RHEUM, V52, P1564, DOI 10.1002-art.21026; Paust S, 2011, NAT IMMUNOL, V131, P500; Paust S, 2010, IMMUNOL REV, V235, P286, DOI 10.1111-j.0105-2896.2010.00906.x; Poon SC, 2003, J INVEST DERMATOL, V121, P184; Prieto Jesús, 2008, J Hepatol, V48, P380, DOI 10.1016-j.jhep.2007.11.007; Romagnani S, 2006, CLIN EXP ALLERGY, V36, P1357, DOI 10.1111-j.1365-2222.2006.02606.x; Rubtsov AV, 2010, AUTOIMMUN REV, V9, P494, DOI 10.1016-j.autrev.2010.02.008; Sader MA, 2005, CLIN ENDOCRINOL, V62, P56, DOI 10.1111-j.1365-2265.2004.02173.x; Saha S, 2011, CLIN REV ALLERG IMMU, V40, P8, DOI 10.1007-s12016-009-8182-6; SanchezGuerrero J, 1996, ARTHRITIS RHEUM, V39, P657, DOI 10.1002-art.1780390418; Schenten D, 2011, ADV IMMUNOL, V109, P87, DOI 10.1016-B978-0-12-387664-5.00003-0; Scofield RH, 2008, ARTHRITIS RHEUM, V58, P2511, DOI 10.1002-art.23701; Streilein J. Wayne, 1994, Journal of Investigative Dermatology, V103, p107S, DOI 10.1111-1523-1747.ep12399400; Szekeres-Bartho J, 2001, INT IMMUNOPHARMACOL, V1, P1037, DOI 10.1016-S1567-5769(01)00035-2; Tanriverdi F, 2003, J ENDOCRINOL, V176, P293, DOI 10.1677-joe.0.1760293; Verthelyi D, 2001, INT IMMUNOPHARMACOL, V1, P983, DOI 10.1016-S1567-5769(01)00044-3; Waldorf KMA, 2008, IMMUNOL INVEST, V37, P631, DOI 10.1080-08820130802205886; Wang J, 2008, CLIN RHEUMATOL, V27, P1183, DOI 10.1007-s10067-008-0937-6; Whitacre CC, 1999, SCIENCE, V283, P1277, DOI 10.1126-science.283.5406.1277; Yancey AL, 2001, INFECT IMMUN, V69, P2865, DOI 10.1128-IAI.69.5.2865-2871.2001; Yeh SH, 2010, ONCOLOGY-BASEL, V78, P172, DOI 10.1159-000315247; Zandman-Goddard G, 2007, AUTOIMMUN REV, V6, P366, DOI 10.1016-j.autrev.2006.10.00114141
Two successful pregnancies in a patient with chemotherapy-induced ovarian failure while on hormone replacement therapy
No full textChemotherapeutic agents administered for the treatment of malignancies can result in the incidence of premature ovarian failure (POF). Ovarian failure is reflected by elevated serum follicle-stimulating hormone (FSH) levels that may reach menopausal levels, at which the chances of a pregnancy are considered extremely rare. We report a case of a 26-year-old female who experienced two successful pregnancies, despite her diagnosis with chemotherapy-induced POF. This case suggests that patients who suffer from POF secondary to chemotherapy might still retain enough ovarian function with good quality oocytes that could support a healthy pregnancy.Anasti JN, 1998, FERTIL STERIL, V70, P1, DOI 10.1016-S0015-0282(98)00099-5; Aslam M F, 2004, J Obstet Gynaecol, V24, P573; Bidet M, 2008, CURR OPIN OBSTET GYN, V20, P416, DOI 10.1097-GCO.0b013e328306a06b; Chasle Sharon, 2003, Eur J Oncol Nurs, V7, P91, DOI 10.1016-S1462-3889(02)00081-9; Check JH, 2008, CLIN EXP OBSTET GYN, V35, P10; Conway GS, 2000, BRIT MED BULL, V56, P643, DOI 10.1258-0007142001903445; Dragojevic-Dikic S, 2009, GYNECOL ENDOCRINOL, V25, P769, DOI 10.3109-09513590903004126; Fernandes AMD, 2002, J REPROD MED, V47, P504; Gelbaya T, 2011, GYNECOL ENDOCRINOL, V27, P1, DOI 10.3109-09513590.2010.501875; Hensley ML, 1998, CRIT REV ONCOL HEMAT, V28, P121, DOI 10.1016-S1040-8428(98)00013-4; KREINER D, 1988, OBSTET GYNECOL, V72, P926; Levi AJ, 2001, FERTIL STERIL, V76, P666, DOI 10.1016-S0015-0282(01)02017-9; Liu J, 2008, BONE MARROW TRANSPL, V41, P275, DOI 10.1038-sj.bmt.1705893; Menashe Y, 1996, J REPROD MED, V41, P207; Nasir J, 1997, CLIN ENDOCRINOL, V46, P217, DOI 10.1046-j.1365-2265.1997.771575.x; Posada MN, 2001, FERTIL STERIL, V75, P647, DOI 10.1016-S0015-0282(00)01781-7; Rebar RW, 2008, ANN NY ACAD SCI, V1135, P138, DOI 10.1196-annals.1429.000; Rebar RW, 2009, OBSTET GYNECOL, V113, P1355, DOI 10.1097-AOG.0b013e3181a66843; Rosendahl M, 2010, FERTIL STERIL, V94, P156, DOI 10.1016-j.fertnstert.2009.02.043; Selvaraj Priya, 2010, J Hum Reprod Sci, V3, P35, DOI 10.4103-0974-1208.63121; Stroud JS, 2009, FERTIL STERIL, V92, P417, DOI 10.1016-j.fertnstert.2008.07.1714; Vandborg M., 2006, Archives of Gynecology and Obstetrics, V273, P387, DOI 10.1007-s00404-005-0096-91
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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