871 research outputs found
sj-docx-1-smo-10.1177_20503121221096534 – Supplemental material for Off-label medication use in pediatrics and associated factors at public hospitals in east Gojjam zone, Ethiopia
No full textSupplemental material, sj-docx-1-smo-10.1177_20503121221096534 for Off-label medication use in pediatrics and associated factors at public hospitals in east Gojjam zone, Ethiopia by Anteneh Belayneh, Eyasu Abatneh, Dehinnet Abebe, Melese Getachew, Bekalu Kebede and Bekalu Dessie in SAGE Open Medicine</p
A Response to the Article “Seroprevalence of Hepatitis B and C Viruses and Their Associated Factors Among Military Personnel at Military Camps in Central Gondar, Ethiopia: A Cross-Sectional Study” [Response to Letter]
No full textAyanaw Dinku Abebe, Muluneh Assefa, Debaka Belete, Getachew Ferede Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaCorrespondence: Muluneh Assefa, Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O.Box 196, Gondar, Ethiopia, Tel +251-944-90-06-00, Email [email protected]; [email protected]
Adverse birth outcome: a comparative analysis between cesarean section and vaginal delivery at Felegehiwot Referral Hospital, Northwest Ethiopia: a retrospective record review [Corrigendum]
No full textAbebe Eyowas F, Negasi AK, Aynalem GE, Worku AG. Pediatric Health, Medicine and Therapeutics. 2016;7:65–70On page 65 Abel Fekadu Dadi should have been listed as an author. The incorrect author list was:Fantu Abebe Eyowas1Ashebir Kidane Negasi1Gizachew Eyassu Aynalem1Abebaw Gebeyehu Worku2The correct author list should have been:Fantu Abebe Eyowas1Ashebir Kidane Negasi1Gizachew Eyassu Aynalem1Abebaw Gebeyehu Worku2Abel Fekadu Dadi2Read the original articl
The impact of banning export of cereals in response to soaring food prices: Evidences from Ethiopia using the new GTAP African database
No full textIn the poorest countries like Ethiopia the spillover effects of a soaring food price is unbearable. To mitigate the recent rise in food prices and the burden on urban poor consumers, different measures have been considered by policy makers. Recently, Ethiopia banned the export of all grain products in a bid to stem huge price hikes. The export of indigenous grains, including the staple grains, like teff, maize, sorghum, and wheat are suspended indefinitely. Using the standard GTAP model and the recent GTAP Africa database, this paper simulates the overall implication of banning export of grains. Regarding the impact on prices, the simulation result tells us that prices are likely to fall. At macro level, the result reveals trade balance will not be decline following such actions. However, it has been shown that in terms of overall welfare the policy has a devastating impact as the country will likely to lose welfare equivalent of $ 148 million.Food price inflation;- export ban;- WTO:- Ethiopia;- GTAP
sj-docx-1-smo-10.1177_20503121231195416 – Supplemental material for Hygienic practice during complementary feeding and its associated factors among mothers/caregivers of children aged 6–24 months in Wolaita Sodo town, southern Ethiopia
No full textSupplemental material, sj-docx-1-smo-10.1177_20503121231195416 for Hygienic practice during complementary feeding and its associated factors among mothers/caregivers of children aged 6–24 months in Wolaita Sodo town, southern Ethiopia by Gizachew Ambaw Kassie, Natnael Atnafu Gebeyehu, Molalegn Mesele Gesese, Endeshaw Chekol Abebe, Misganaw Asmamaw Mengstie, Mohammed Abdu Seid, Wubet Alebachew Bayih, Sefineh Fenta Feleke, Natnael Amare Tesfa, Tadesse Asmamaw Dejenie, Berihun Bantie, Yenealem Solomon Kebede, Melkamu Aderajew Zemene, Anteneh Mengist Dessie, Denekew Tenaw Anley and Getachew Asmare Adella in SAGE Open Medicine</p
Trans Rights: A detailed analysis of access to gender affirming treatments by minors and the differing approaches taken by Member States in the European Union
No full textIn this paper the author will be discussing the varying approaches by Member States in the European Union regarding the rights of Minors to access/undertake gender affirming treatments. This paper shall have a particular focus on the varying approaches taken by the Republic of Ireland, United Kingdom and the Netherlands in minors having access to gender affirming treatments. The Netherlands has developed a protocol for gender affirming intervention which has been deemed to be the benchmark for providing treatment for minors suffering from gender dysphoria. The protocol developed by the Netherland vastly differs from other Member States such as the United Kingdom and Ireland. The basis for the differing views by such member states lies on the basis of health officials that intervention can be a detriment to minors instead of having a benefit. The varying approaches by Member States raises the question of what can be considered to be the appropriate approach to be undertaken in providing gender affirming treatment to minors and the lines that must be drawn between what can be considered in what is deemed to be providing minors with the right to receive appropriate care against what can be considered to be medical malpractice
Inappropriate prescribing of antithrombotic therapy in Ethiopian elderly population using updated 2015 STOPP/START criteria: a cross-sectional study
No full textHenok Getachew, Akshaya Srikanth Bhagavathula, Tamrat Befekadu Abebe, Sewunet Admasu Belachew Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Background: Inappropriate use of antiplatelets and anticoagulants among elderly patients increases the risk of adverse outcomes. The aim of this study was to assess the prevalence of inappropriate prescribing of antithrombotic therapy in hospitalized elderly patients. Methods: A retrospective cross-sectional, single-center study was conducted at the Gondar University Hospital. A total of 156 hospitalized elderly patients fulfilling the inclusion/­exclusion criteria were included in the study. The Screening Tool for Older Person’s Prescription/Screening Tool to Alert doctors to Right Treatment criteria version 2 were applied to patients’ data to identify the total number of inappropriate prescribing (IPs) including potentially inappropriate medications and potential prescribing omissions. Results: A total of 70 IPs were identified in 156 patients who met the inclusion criteria. Of these, 36 (51.4%) were identified as potentially inappropriate medications by the Screening Tool for Older Person’s Prescription criteria. The prevalence of IP per patient indicated that 58 of the 156 (37.2%) patients were exposed to at least one IP. Of these, 32 (55.2%) had at least one potentially inappropriate medication and 33 (56.9%) had at least one potential prescribing omission. Patients hospitalized due to venous thromboembolism (adjusted odds ratio [AOR] =29.87, 95% confidence interval [CI], 1.26–708.6), stroke (AOR =7.74, 95% CI, 1.27–47.29), or acute coronary syndrome (AOR =13.48, 95% CI, 1.4–129.1) were less likely to be exposed to an IP. An increase in Charlson comorbidity index score was associated with increased IP exposure (AOR =0.60, 95% CI, 0.39–0.945). IPs were about six times more likely to absent in patients prescribed with antiplatelet only therapy (AOR =6.23, 95% CI, 1.90–20.37) than those receiving any other groups of antithrombotics. Conclusion: IPs are less common in elderly patients primarily admitted due to venous thromboembolism, stroke, and acute coronary syndrome, and those elderly patients prescribed with only antiplatelet. Patients with higher Charlson comorbidity index were, however, associated with increased IPs exposure. Our study may guide further research to reduce high-risk prescription of antithrombotics in the elderly. Keywords: prevalence, inappropriate prescribing, antithrombotic, STOPP/START criteria, elderly, Ethiopi
Key Considerations: Social Science Perspectives for Emergency Response to the Conflict in Northern Ethiopia || ቁልፍ እይታወች፡ በሰሜን ኢትዮጵያ ለተፈጠረው ግጭት የማህበራዊ ሳይንስ የአደጋ ጊዜ ምላሽ ምልከታዎች
No full textEthiopia is currently experiencing several intersecting humanitarian crises including conflict, climatic shocks, COVID-19, desert locust infestation and more. These intersecting crises are affecting nearly 30 million people and resulting in food insecurity, displacement and protection risks. As of February 2022, over 2.5 million people were estimated to have been displaced as a result of the ongoing conflict-driven humanitarian crisis in the Northern Ethiopian regions of Tigray, Amhara and Afar that began in November 2020. As of May 2022, 9.4 million were in need of humanitarian aid in the region. Private and public assets have been destroyed, already fragile livelihoods damaged, and communities left in dire need of support.
This brief outlines important contextual factors and social impacts of the Northern Ethiopian crisis and offers key considerations to improve the effectiveness of the humanitarian response. It is based on a rapid review of existing published and grey literature and conversations with relevant stakeholders, including people from affected regions and humanitarian responders. This brief is part of a series authored by participants from the SSHAP Fellowship and was written by Heran Abebe and Getachew Belaineh from Cohort 2. It was reviewed by Ezana Amdework (Addis Ababa University), Kelemework Tafere (Mekelle University), and Yomif Worku (independent humanitarian advisor), and was supported by Tabitha Hrynick from the SSHAP team at the Institute of Development Studies. The brief is the responsibility of the SSHAP.ኢትዮጵያ በአሁኑ ወቅት በርካታ ተደራራቢ ሰብአዊ ቀውሶች፤ ግጭት፣ የአየር ንብረት መዛባት፣ኮቪድ-19፣ የበረሃ አንበጣ እና ሌሎችም ጨምሮ እያጋጠማት ነው። እነዚህ ተደራራቢ ቀውሶች ወደ 30 ሚሊዮን የሚጠጋ ህዝብን ለምግብ ዋስትና እጦት፣ መፈናቀል እና የጥበቃ ስጋቶች ዳርገዋል፡፡ 1,2 በሰሜን ኢትዮጵያ በሚገኙት በትግራይ፣ አማራና አፋር ክልሎች በህዳር ወር 2013 በተጀመረዉና ቀጣይነት ባለዉ ግጭትና ግጭቱን ተከትሎ በተከሰተዉ ሰብአዊ ቀውስ ምክንያት፣ በየካቲት ወር 2014 ከ2.5 ሚሊዮን በላይ የሚገመት ህዝብ የተፈናቀለ ሲሆን በግንቦት ወር 2014 ብቻ 9.4 ሚሊዮን የክልሉ ህዘብ ሰብዓዊ እርዳታ ያስፈልጋቸው ነበር ፡፡ 3 የግል እና የህዝብ ሀብት ወድሟል፣ ቀድሞውንም የነበረዉ ደካማ ኑሮ ተጎድቷል፣ ማህበረሰቦች ከፍተኛ ድጋፍ ያስፈልጋቸዋል።.
ይህ ፅሁፍ የሰሜን ኢትዮጵያ ቀውስ ጠቃሚ አውዳዊ ሁኔታዎችን እና ማህበራዊ ተፅእኖዎችን ይዘረዝራል። በተጨማሪም የሰብአዊ ምላሽን ውጤታማነት ለማሻሻል ቁልፍ እይታወችን ያቀርባል፡፡ ፅሁፉም የተዘጋጀዉ ነባር የታተሙ እና ያልታተሙ ጽሑፎችን በፍጥነት በመገምገምና እና ከሚመለከታቸው ባለድርሻ አካላት ጋር ፣ ከተጎዱ ክልሎች የመጡ ሰዎችን እና የሰብአዊ እርዳታ ሰጪዎችን ጨምሮ በተደረጉ ውይይቶች ነዉ፡፡ ይህ ጽሁፍ ፤ ማህበራዊ ሳይንስ በሰብአዊ ድርጊት መድረክ (Social Science in Humanitarian Action Platform Fellowship) ተሳታፊዎች መድረክ በሚዘጋጀው ተከታታይ ክፍል ላይ አንድ አካል ሲሆን ከምድብ 2 (cohort 2) በሄራን አበበ እና ጌታቸው በላይነህ የተጻፈ ነዉ፡፡ ይኽ ጽሁፍ በኢዛና አምደወርቅ (አዲስ አበባ ዩኒቨርሲቲ) ፣ቀለመወርቅ ታፈረ (መቐለ ዩኒቨርሲቲ) እና ዮሚፍ ወርቁ (ገለልተኛ የሰብዓዊ ጉዳዮች አማካሪ) ተገምግሞ በልማት ጥናት ተቋም (Institute of Development Studies) ስር በሚገኘው ማህበራዊ ሳይንስ በሰብአዊ ድርጊት መድረክ (SSHAP) ቡድን አባል በሆነችው በጣቢታ ህሪኒክ ድጋፍ የተዘጋጀ ነዉ፡፡ ጽሁፉን በኃላፊነት ያዘጋጀዉ ደግሞ ማህበራዊ ሳይንስ በሰብአዊ ድርጊት መድረክ (SSHAP) ነው።</p
Systematic Review of Safety of RTS,S with AS01 and AS02 Adjuvant Systems Using Data from Randomized Controlled Trials in Infants, Children, and Adults
No full textWubetu Yihunie,1 Bekalu Kebede,1 Bantayehu Addis Tegegne,1 Melese Getachew,1 Dehnnet Abebe,1 Yibeltal Aschale,2 Habtamu Belew,2 Bereket Bahiru3 1Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Medical Laboratory Science, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia; 3Department of Pharmacy, College of Medicine and health sciences, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Wubetu Yihunie, Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia, Tel +251 910112391, Email [email protected]: Emergence of antimalarial drugs and insecticides resistance alarms scientists to develop a safe and effective malaria vaccine. A pre-erythrocytic malaria vaccine called RTS,S has made great strides.Aim: The review was aimed to assess the safety of the candidate malaria vaccine RTS,S with AS01 and AS02 adjuvants using data from Phase I–III randomized controlled clinical trials (RCTs).Methods: This systematic review was conducted based on PRISMA 2020. Regardless of time of publication year, all articles related with safety of RTS,S, RCTs published in the English language were included in the study. The last search of databases, and registry was conducted on 30 May, 2022. Pubmed, Google Scholar, Cochrane Library, Wiley Online Library, and Clinical trials.gov were thoroughly searched for accessible RCTs on the safety of RTS,S malaria vaccine. The studies were screened in three steps: duplicate removal, title and abstract screening, and full-text review. The included studies’ bias risk was assessed using the Cochrane risk of bias tool for RCTs. This systematic review is registered at Prospero (registration number: CRD42021285888). The qualitative descriptive findings from the included published studies were reported stratified by clinical trial phases.Findings: A total of thirty-five eligible safety studies were identified. Injection site pain and swelling, febrile convulsion, fever, headache, meningitis, fatigue, gastroenteritis, myalgia, pneumonia, reactogenicity, and anemia were the most commonly reported adverse events. Despite few clinical trials reported serious adverse events, none of them were related to vaccination.Conclusion: Most of the adverse events observed from RTS,S/AS01 and RTS,S/AS02 malaria vaccines were reported in the control group and shared by other vaccines. Hence, the authors concluded that both RTS,S/AS01 and RTS,S/AS02 malaria vaccines are safe.Keywords: RTS,S/AS01, RTS,S/AS02, safety, systematic review, randomized controlled trial
Phenotypic Characterization for Identification, Conservation and Sustainable Utilization of Boset and Minjar Shenkora Goats of Ethiopia
No full textThis study was conducted on a total of 776 goats (part of Central highland goat breeds of Ethiopia),
306 from Boset district of Oromia region and 470 were from Minjar Shenkora district of Amhara
region. A format developed by using food and agriculture organization discerption list was used for
recording of morphological traits, bodyweight and linear body measurements. Both qualitative and
quantitative traits were recorded from randomly sampled mature goats and the data were analyzed
using SAS software. The goat type in the study area was characterized by a higher proportion of
plain coat color patterns (62.5). Ingeneral, the majority (98.4%) of the studied goats were horned
and characterized by backward orientation (67%) with a straight shape (49.3%). They presented a
concave facial profile (73.8%), slop up toward the rump back profile (66.2%), no wattle (99.6%),
no toggle (90.7%), no ruff (85.9%) and no beard (57.3%). The location had a significant effect on
body weight and some other linear body measurements. Traits like body length, rump length, horn
length, head length, head width and shin circumference were significantly higher in Boset district.
In contrast, rump width and cannon bone length were significantly lower. The mean body weight
of male goats in Boset and Minjar Shenkora district were 30.5±1.05 kg with a range of 16 to 47 and
27.5±0.56 with a range of 13 to 57, respectively. While for female counterpart mean body weights
(kg) were 28.4±0.35 with a range of 17 to 45 for Boset and 27.5±0.33 with a range 15 to 57 for
Minjar Shenkora district. Heart girth had the highest correlation with body weight in both sexes and
shoulder width in Boset male goats. The wider variation in most quantitative measurement traits
would open an opportunity for further improvement, conservation and utilization work
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