1,721 research outputs found

    Jane Mayer, 32nd Annual ODU Literary Festival

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    Jane Mayer joined The New Yorker as a staff writer in 1995. She writes about politics for the magazine, and has been covering the war on terror. Recent subjects include Alberto Mora and the Pentagon’s secret torture policy, how the United States out-sources torture, the prison at Guantánamo Bay, and the legality of C.I.A. interrogations. She has also written about George W. Bush, the bin Laden family, and Sarah Palin. Mayer was the 2008 winner of the John Chancellor Award for Journalistic Excellence. She was also a 2009 finalist for the National Book Award and the National Book Critics Circle Award. Mayer is the author of the best-selling 2008 book The Dark Side: The Inside Story of How the War in Terror Turned into a War on American Ideals, which was chosen as one of the ten best books of the year by The New York Times, The Economist Magazine, Salon, Slate and Bloomberg

    POLICY SPACE: WHAT, FOR WHAT, AND WHERE?

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    The paper examines how developing countries can use existing policy space, and enlarge it, without opting out of international commitments. It argues that: (i) a meaningful context for policy space must extend beyond trade policy and include macroeconomic and exchange-rate policies that will achieve developmental goals more effectively; (ii) policy space depends not only on international rules but also on the impact of international market conditions and policy decisions taken in other countries on the effectiveness of national policy instruments; and (iii) international integration affects policy space through several factors that pull in opposite directions; whether it increases or reduces policy space differs by country and type of integration.

    The Roman Inquisition : A Papal Bureaucracy and Its Laws in the Age of Galileo /

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    As Thomas F. Mayer demonstrates in this first study of the Roman Inquisition as an institution, the Inquisition underwent constant modification as it expanded. Originally aimed to eradicate Protestant heresy, it went beyond medieval antecedents by becoming a highly articulated centralized organ directly dependent on the pope.As Thomas F. Mayer demonstrates in this first study of the Roman Inquisition as an institution, the Inquisition underwent constant modification as it expanded. Originally aimed to eradicate Protestant heresy, it went beyond medieval antecedents by becoming a highly articulated centralized organ directly dependent on the pope.Electronic reproduction. ,Mode of access: Internet via World Wide Web.Thomas F. Mayer is Professor of History at Augustana College. He is author of Reginald Pole: Prince and Prophet, and editor and translator of The Trial of Galileo, 1612-1633.Description based on online resource; title from PDF title page (publisher’s Web site, viewed March 24, 2015

    Unique profile of antimicrobial peptide expression in polymorphic light eruption lesions compared to healthy skin, atopic dermatitis, and psoriasis

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    Polymorphic light eruption (PLE) has been attributed to type IV, most likely delayed-type hypersensitivity response (adaptive immunity) but little is known on innate immunity, especially antimicrobial peptides (AMPs) in the disease. Abnormalities in AMP expression have been linked to pathological skin conditions such as atopic dermatitis (AD) and psoriasis

    The Roman Inquisition on the Stage of Italy, c. 1590-1640 /

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    Drawing on the Roman Inquisition's own records, diplomatic correspondence, local documents, newsletters, and other sources, Thomas F. Mayer provides an intricately detailed account of the ways the Inquisition operated to serve the papacy's long-standing political aims in Naples, Venice, and Florence between 1590 and 1640.Drawing on the Roman Inquisition's own records, diplomatic correspondence, local documents, newsletters, and other sources, Thomas F. Mayer provides an intricately detailed account of the ways the Inquisition operated to serve the papacy's long-standing political aims in Naples, Venice, and Florence between 1590 and 1640.Electronic reproduction. ,Mode of access: Internet via World Wide Web.Thomas F. Mayer is author of The Roman Inquisition: A Papal Bureaucracy and Its Laws in the Age of Galileo, also available from the University of Pennsylvania Press, and Reginald Pole: Prince and Prophet. He is also editor and translator of The Trial of Galileo, 1612-1633.Description based on online resource; title from PDF title page (publisher’s Web site, viewed March 24, 2015

    Rudolf Mayer

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    The bachelor thesis deals with the life and work of Rudolf Mayer. In the first part, attention is given to the author and the reception of his work presented in period magazines and newspapers from the poet´s death in 1945. During the second part of his work is examined in terms of literary discursivity the subjective romanticism

    Alumni author Khaled Hosseini

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    Color portrait of alumnus author Khaled Hosseini sitting on the Mayer Theatre stage

    Platelet-Activating Factor Blockade Inhibits the T-Helper Type 17 Cell Pathway and Suppresses Psoriasis-Like Skin Disease in K5.hTGF-β1 Transgenic Mice

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    Platelet-activating factor (PAF), a potent biolipid mediator, is involved in a variety of cellular transduction pathways and plays a prominent role in inducing inflammation in different organs. We used K5.hTGF-beta 1 transgenic mice, which exhibit an inflammatory skin disorder and molecular and cytokine normalities with strong similarities to human psoriasis, to study the pathogenic role of PAF. We found that injecting PAF into the skin of transgenic mice led to inflammation and accelerated manifestation of the psoriatic phenotype by a local effect. In contrast, injecting mice with PAF receptor antagonist PCA-4248 lowered the PAF level (most likely by depressing an autocrine loop) and neutrophil, CD68(+) cell (monocyte/macrophage), and CD3(+) T-cell accumulation in the skin and blocked progression of the psoriasis-like phenotype. This effect of PAF blockade was specific and similar to that of psoralen-UV-A and was paralleled by a decrease in abnormally elevated mRNA and/or protein levels of T-helper type 17 cell-related cytokines IL-17A, IL-17F, IL-23, IL-12A, and IL-6 and its transcription factor signal transducer and activator of transcription 3. In contrast, PCA-4248 treatment up-regulated mRNA levels of cyclooxygenase-2 and IL-10 in dorsal skin and release of IL-10 in serum and skin. Interfering with PAF may offer the opportunity to develop novel therapeutic strategies for inflammatory psoriasis and associated comorbidities, including metabolic syndrome and atherosclerosis, in which the IL-17 axis may be involved. (Am J Pathol 2011, 178:699-708; DOI: 10.1016/j.ajpath.2010.10.008)Austrian National Bank [11729, 13279]; Medical University of Gra
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