127 research outputs found
Data Set of PLOS Computational Paper PCOMPBIOL-D-18-02181R1
No full textFigures Data of PLOS Computational paper:Modeling of the axon plasma membrane structure and its effects on protein diffusionAuthors: Yihao Zhang, Anastasios V. Tzingounis, and George LykotrafitisCorresponding Author: George Lykotrafitis, Ph.D.University of ConnecticutStorss, CT UNITED STATES</div
The influence of graft choice on isokinetic muscle strength 4-24 months after anterior cruciate ligament reconstruction
No full textRegaining adequate strength of the quadriceps and hamstrings after anterior cruciate ligament (ACL) reconstruction is important for maximizing functional performance. However, the outcome of muscle strength after either BPTB or hamstrings autograft is unclear given the plethora of published studies that report post-operative muscle strength. The purpose of this study was to systematically compare the muscle strength of patients who have undergone ACL reconstruction using either Bone Patellar Tendon Bone (BPTB) or Hamstrings (HST) autograft. The databases of MEDLINE, Cinahal and EMBASE were systematically searched for articles that report muscle strength outcome following ACL reconstruction. The quality of the studies was evaluated and a meta-analysis of the muscle strength outcomes was conducted on reported data. Fourteen studies were included in this systematic review: eight Randomized Control Studies (RCT) and six non-Randomized Control Studies (non-RCT). A meta-analysis was performed involving eight of the included studies (4 RCTs andamp; 3 non-RCTs). At 60A degrees/s and 180A degrees/s, patients with BPTB graft showed a greater deficit in extensor muscle strength and lower deficit in flexor muscle strength compared with patients with HST. This systematic review of Level III evidence showed that isokinetic muscle strength deficits following ACL reconstruction are associated with the location of the donor site. These deficits appear to be unresolved up to 2 years after ACL reconstruction. III.The original publication is available at www.springerlink.com:Sofia A Xergia, Jodie A McClelland, Joanna Kvist, Haris S Vasiliadis and Anastasios D Georgoulis, The influence of graft choice on isokinetic muscle strength 4-24 months after anterior cruciate ligament reconstruction, 2011, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, (19), 5, 768-780.http://dx.doi.org/10.1007/s00167-010-1357-0Copyright: Springer Science Business Mediahttp://www.springerlink.com
COVID-19-associated Guillain–Barrè Syndrome and Urinary Dysfunction: A case report
No full textSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection can cause multiple systemic and neurological complications, including Guillain–Barrè Syndrome (GBS). In this report we describe for the first time, urinary dysfunction in a patient with COVID-19. We reported a 41-years-old female patient with complaints of an increased generalized muscular weakness associated with progressive difficulty in walking. Four days earlier, patient complained of fever, diarrhea, and general weakness, and the RT-PCR was positive for COVID-19 infection. Due to the worsening of neurological symptoms, a neurophysiological examination on nervous conduction was performed and the diagnosis was suggestive of GBS. Two weeks later, patient developed two consecutive episodes of acute urinary retention that requested the placement of indwelling transurethral catheter. Patient started assuming selective alpha-1 adrenergic antagonist in association with 4 clean intermittent catheterization/die. Four months later, women continued the therapy and the ultrasound evaluation revealed non-pathologic post-void residual volume. Therefore, patient started to void spontaneously again and alpha-blockers were discontinued. We report for the first time a case of severe voiding disorder in a patient with COVID-19 associated GBS. Timely bladder drainage should be adopted to avoid irreversible detrusor damage
Progressive Damage Accumulation Process of CFRP Cross-Ply Laminates during the Early Fatigue Life
No full textThe present work aims at investigating the progressive damage accumulation process of CFRP laminates in an interactive scheme, with a special focus on the early fatigue life where mainly matrix-dominant damage accumulates and stiffness degrades significantly. An in-situ damage monitoring system, containing edge observation, digital image correlation and acoustic emission techniques, was established to characterize and quantify the accumulation of transverse cracks and delamination. Two cross-ply configurations ([0/902]s and [02/904]s) and different stress levels were involved in the experimental campaign. Dependent crack ratio was proposed to reflect the interaction among transverse cracks, and saturated crack density was used to represent the interactive level between transverse cracks and delamination. Results showed that generation of transverse cracks and their interaction govern the early fatigue damage accumulation of the [0/902]s laminates, while not only the interaction among cracks but also the interaction between both damage mechanisms were observed for the [02/904]s laminates.Structural Integrity & Composite
Where, when and in which social context do good ideas evolve in the distributed work environment of knowledge workers?
No full textThesis (S.M.)--Massachusetts Institute of Technology, Dept. of Architecture, 2009.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (p. 158-160).The nature of work is changing. Until recently, the majority of people worked in fixed, team-based collaborations in collocated settings for fixed periods of time. Currently we are experiencing a major shift towards distributed work. D-work is multi-tasking (workers participate in many projects and teams that often change), multi-locational (work is conducted by people located in different divisions, firms, organizations and time-zones) and mobile (people conduct work while transiting). D-Work changes the definition of the traditional office and blurs the boundaries between home, workplace and the city. Homes will have to accommodate work, businesses must adapt their policies and office spaces to D-work and cities have to adapt to new patterns of mixed work-live units. At the moment, workers, managers and designers have become less aware of where, when, with whom and during which activities, does the most productive and creative work take place. In an effort to tackle the above mentioned issue, we developed a methodology that combines Context-Aware Experience Sampling with traditional ethnographic tools. Our system is composed of a Bluetooth-based positioning system, a context-aware self-report survey administered on mobile phones and traditional questionnaires. The methodology was tested via a four week case study on innovation that was conducted in a marketing firm based in Helsinki. During the study we collected data from eleven participants about the occurrence of work-related ideas and barriers inside and outside the office space.(cont.) All participants provided us with information about their work habits by filling out a questionnaire prior to the beginning of the study. By juxtaposing their answers to their actual work-life data that we collected, similarities and discrepancies between the two emerged that helped us to understand and assess their work behavior. General results as well as personal reports that were compiled for three subjects are presented and analyzed. An overall assessment of the system and suggested improvements based on results and participant feedback are also discussed.by Anastasios Dimas.S.M
VELOCITY AT LACTATE THRESHOLD AND RUNNING ECONOMY MUST ALSO BE CONSIDERED ALONG WITH MAXIMAL OXYGEN UPTAKE WHEN TESTING ELITE SOCCER PLAYERS DURING PRESEASON
No full textPart of the Biomechanics Commons This Article is brought to you for free and open access by the Biomechanics Research Building a
Micromechanical modeling of rate-dependent off-axis failure in thermoplastic composites
No full textA micromechanical framework for modeling failure in unidirectional (UD) thermoplastic composites under rate-dependent off-axis loading is presented, with the aim to predict and analyze transverse matrix cracking under various load conditions. The onset of global softening in the micromodel corresponds to macroscopic matrix crack initiation. The problem addressed in this study is to include matrix plasticity and microcracking in the failure analysis of UD composites. A thin slice representative volume element (RVE) with periodic boundary conditions is used, which enables representation of 3D stress states. The testing conditions of a constant prescribed strain-rate and an off-axis uniaxial stress state are reproduced in the model with a dedicated arclength control method. The studied material system is carbon/PEEK composite material, where plasticity in the matrix is represented with the Eindhoven Glassy Polymer (EGP) constitutive law, while the fibers are modeled as transversely isotropic elastic material. In order to account for microcracking in the matrix, a cohesive surface methodology is applied. Cohesive elements are added on the fly with a stress-based initiation criterion. For this purpose, a power law microcrack initiation criterion is proposed. After initiation, the microcracking process is governed by a mixed-mode damage cohesive law. Geometric nonlinear effects are also included in the cohesive model, such that cohesive forces include material as well as geometric contributions. The model is validated with experimental data from tensile tests on UD material at different off-axis angles and strain-rates. The obtained maximum stress levels are used to generate Tsai-Hill failure envelopes for macroscopic transverse crack initiation. Additional capabilities of the model are demonstrated through examples with different fiber-volume ratios and temperature conditions.Applied Mechanic
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