93 research outputs found

    Kurbinovo, Georgskirche

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    Beschriftung Hallensleben:„Kurbinovo, H. Georgios, 1191 / Apsis, Zone II, Südseite / [Bild] / Patriarchen bzw. Bischöfe (Chrysos- / tomos, Athanas., Achilleios, Nikolaos“ [Plan siehe 023-182]http://difab.univie.ac.at (Digitales Forschungsarchiv Byzanz

    Development of effective hospital-based antibiotic stewardship program. The role of infectious disease specialist

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    Excessive antibiotic consumption and misuse is one of the main factors responsible for the emergence of antibiotic-resistant bacteria and has been associated with increased health care costs. Active intervention is necessary in changing antimicrobial prescribing practices. The Infection Control Committee and the administration of our hospital decided to implement an antibiotic stewardship program beginning in January 2016 in order to reduce inappropriate antibiotic use and to combat antibiotic resistance through improved prescribing practices. The antimicrobial stewardship team includes an ID specialist, physicians, infection control nurses, a microbiologist and a pharmacist who are responsible for the implementation of the program. Preauthorization by an ID specialist and prospective review is necessary for all pharmacy orders of antibiotics under restriction. Pre-intervention, we collected Pharmacy and hospital data regarding antibiotic consumption and numbers of patient-days for the years 2013-2015. We calculated antibiotic use in Defined Daily Doses (DDDs)/100 patient-days. After one year, the antibiotic stewardship program was effective in reducing consumption of most antibiotics. The result of the implementation of the program in our hospital was a reduction about 17% of antibiotic DDDs/100 patient-days and about 21% of the antibiotic cost/100 patient-days. Education is an essential element of our program in order to influence prescribing behavior. Lectures and brochures are used to supplement strategies. Antibiotic stewardship programs have been shown from many studies to improve patient outcomes, reduce antibiotic resistance and save money

    EXTRA: An open platform for reconfigurable architectures

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    Reconfigurable hardware is becoming increasingly mainstream, evolving to a valid alternative to Graphics Processing Units-based hardware accelerators. However, several major challenges remain for migrating existing software to heterogeneous reconfigurable architectures. The EXTRA project aims to develop an integrated environment for developing and programming reconfigurable architectures. The EXTRA platform enables the joint optimization of architecture, tools, and reconfiguration technology, and targets the future High Performance Computing hardware nodes. In this paper, we present four innovative EXTRA technologies: (1) a hardware-software co-design framework; (2) a parallel memory system; (3) a decoupled access execute framework for reconfigurable technology; and (4) transparent access and virtualization of reconfigurable hardware accelerators. Moreover, we describe how the EXTRA technologies targeting the Amazon F1 cloud compute instances can be used in medical applications such as the retinal image segmentation

    Variable packet size buffered crossbar (cicq) switches

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    Abstract — One of the most widely used architectures for packet switches is the crossbar. A special version of it is the buffered crossbar, where small buffers are associated with the crosspoints; this simplifies scheduling and improves its efficiency and QoS capabilities to the point where the switch needs no internal speedup. Furthermore, by supporting variable length packets throughout a buffered crossbar: (a) there is no need for segmentation and reassembly (SAR) circuits; (b) no speedup is necessary to support SAR; and (c) synchronization between the input and output clock domains is simplified. In turn, the lack of SAR and speedup mean that no output queues are needed, either. In this paper we present an architecture, a chip layout and cost analysis, and a performance evaluation of such a 300 Gbps buffered crossbar operating on variable-size packets. The proposed organization is simple yet powerful, can be implemented using modern technology, and, as the performance results demonstrate, it clearly outperforms unbuffered crossbars.

    The first Facial Landmark Tracking in-the-Wild Challenge: benchmark and results

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    Detection and tracking of faces in image sequences is among the most well studied problems in the intersection of statistical machine learning and computer vision. Often, tracking and detection methodologies use a rigid representation to describe the facial region 1, hence they can neither capture nor exploit the non-rigid facial deformations, which are crucial for countless of applications (e.g., facial expression analysis, facial motion capture, high-performance face recognition etc.). Usually, the non-rigid deformations are captured by locating and tracking the position of a set of fiducial facial landmarks (e.g., eyes, nose, mouth etc.). Recently, we witnessed a burst of research in automatic facial landmark localisation in static imagery. This is partly attributed to the availability of large amount of annotated data, many of which have been provided by the first facial landmark localisation challenge (also known as 300-W challenge). Even though now well established benchmarks exist for facial landmark localisation in static imagery, to the best of our knowledge, there is no established benchmark for assessing the performance of facial landmark tracking methodologies, containing an adequate number of annotated face videos. In conjunction with ICCV’2015 we run the first competition/challenge on facial landmark tracking in long-term videos. In this paper, we present the first benchmark for long-term facial landmark tracking, containing currently over 110 annotated videos, and we summarise the results of the competition

    Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial (Nature Medicine, (2021), 27, 10, (1752-1760), 10.1038/s41591-021-01499-z)

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    In the version of this Article initially published, there was an error in the author affiliations. Specifically, affiliation 27, corresponding to author Carlo Selmi, has been corrected from “Humanitas Research Hospital, Milan, Italy” to read: “Department of Biomedical Sciences, Humanitas University, Milan, Italy & IRCCS Humanitas Research Hospital, Milan, Italy.” The change has been made to the online version of the Article

    Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial (Nature Medicine, (2021), 27, 10, (1752-1760), 10.1038/s41591-021-01499-z)

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    In the version of this Article initially published, there was an error in the author affiliations. Specifically, affiliation 27, corresponding to author Carlo Selmi, has been corrected from “Humanitas Research Hospital, Milan, Italy” to read: “Department of Biomedical Sciences, Humanitas University, Milan, Italy & IRCCS Humanitas Research Hospital, Milan, Italy.” The change has been made to the online version of the Article. © The Author(s) 2021

    D2.1: Application requirements and specifications

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    Basic taxonomy of datacenter applications in terms of QoS requirements, and application-side requirements that are crucial for each of the considered VINEYARD use cases
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