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I parassiti nell’allevamento bovino e bufalinonella prospettiva del veterinario aziendale
No full text
Efficacy of moxidectin microsphere sustained release formulation for the prevention of subcutaneous filarial (Dirofilaria repens) infection in dogs
No full textA study was carried out to assess the efficacy of a moxidectin microsphere sustained release (SR) injectable formulation (Guardian® SR Iniettabile, Fort Dodge®) for the prevention of Dirofilaria repens infection in experimentally infected dogs. On day 0, 18 Beagle dogs, 9 male dogs and 9 female dogs, weighing 12-16kg were ranked in ascending order of body weight (b.w.) and blocked into pairs. Within each pair, dogs were allocated to Group 1 or Group 2 at random. On the same day, dogs in Group 1 were injected with 0.05ml/kg b.w. of saline solution and dogs in Group 2 were injected with moxidectin SR at the label dose 0.17mg/kg b.w. (0.05ml/kg b.w.). Six months after moxidectin SR or saline injection, on day 180, each dog in the two groups was challenged with 50 infective larvae of D. repens collected from laboratory-reared, experimentally infected Aedes aegypti. Dogs were humanely euthanized on day 380 of the study, approximately 7 months from D. repens challenge. At necropsy, no worms were found in dogs treated with moxidectin SR (Group 2) while adult worms were found in saline-treated dogs (total 90; 38 males and 52 females; arithmetic mean 10, standard error 0.96, median 9, range 7-15) (Group 1 vs Group 2 P<0.001). In this experimental study, moxidectin SR injectable showed full efficacy (100%) lasting at least 6 months, and is able to prevent subcutaneous D. repens patent infection throughout the entire transmission season in Europe. © 2010 Elsevier B.V
Infestazioni parassitarie polmnari del gatto: Aelurostrongylus abstrusus
No full textNumerosi parassiti possono infestare il tratto
respiratorio del gatto. Aelurostrongylus abstrusus
è uno dei più importanti parassiti a localizzazione
polmonare dei felidi. La prevalenza, di questo
nematode a distribuzione mondiale, dipende da
stile di vita (all’interno, all’esterno), origine geografica
e metodi utilizzati per la diagnosi. Il parassita è
ancora considerato da alcuni veterinari pratici
sporadico e relativamente poco patogeno. I gatti
si infestano attraverso l’assunzione di chiocciole
o più facilmente di ospiti paratenici. Solitamente
la malattia ha un decorso cronico con sintomi
respiratori poco patognomonici. Le manifestazioni
cliniche variano da subclinica a grave e dipendono
dal carico parassitario, dall’età dell’animale, dalla
risposta immunitaria e dalla presenza di malattie
concomitanti. I gatti randagi e liberi di avere
l’accesso all’esterno hanno un rischio maggiore
di contrarre l’infezione soprattutto in aree endemiche.
Gli esami copromicroscopci devono essere considerati
come il primo paso per diagnosticare l’infestazione
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