175,489 research outputs found

    Blais & Geiser (2018) Confirmatory Factor Analyses of PCL-5

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    Summary of confirmatory factor analyses for PCL-5 items for data reported in Blais & Geiser (2018). Mplus output files can be viewed using Notepad or MS Word. Blais, R. K., & Geiser, C. (2018). Specific PTSD symptom clusters mediate the association of military sexual trauma and sexual function and satisfaction in female service members/veterans. Manuscript submitted for publication

    Carl Friedrich Geiser and Ferdinand Rudio : the men behind the first International Congress of Mathematicians

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    The first International Congress of Mathematicians (ICM) was held in Zurich in 1897, setting the standards for all future ICMs. Whilst giving an overview of the congress itself, this thesis focuses on the Swiss organisers, who were predominantly university professors and secondary school teachers. As this thesis aims to offer some insight into their lives, it includes their biographies, highlighting their individual contributions to the congress. Furthermore, it explains why Zurich was chosen as the first host city and how the committee proceeded with the congress organisation. Two of the main organisers were the Swiss geometers Carl Friedrich Geiser (1843-1934) and Ferdinand Rudio (1856-1929). In addition to the congress, they also made valuable contributions to mathematical education, and in Rudio’s case, the history of mathematics. Therefore, this thesis focuses primarily on these two mathematicians. As for Geiser, the relationship to his great-uncle Jakob Steiner is explained in more detail. Furthermore, his contributions to the administration of the Swiss Federal Institute of Technology are summarised. Due to the overarching theme of mathematical education and collaborations in this thesis, Geiser’s schoolbook "Einleitung in die synthetische Geometrie" is considered in more detail and Geiser’s methods are highlighted. A selection of Rudio’s contributions to the history of mathematics is studied as well. His book "Archimedes, Huygens, Lambert, Legendre" is analysed and compared to E W Hobson’s treatise "Squaring the Circle". Furthermore, Rudio’s papers relating to the commentary of Simplicius on quadratures by Antiphon and Hippocrates are considered, focusing on Rudio’s translation of the commentary and on "Die Möndchen des Hippokrates". The thesis concludes with an analysis of Rudio’s popular lectures "Leonhard Euler" and "Über den Antheil der mathematischen Wissenschaften an der Kultur der Renaissance", which are prime examples of his approach to the history of mathematics

    Blais & Geiser MST, PTSD, and Suicidal Ideation Path Analyses

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    Mplus output files for analyses reported in Blais, R. K., & Geiser, C. (2018). Depression and PTSD-related anhedonia mediate the association of military sexual trauma and suicidal ideation in female service mem-bers/veterans. Manuscript submitted for publication

    Geiser et al. Longitudinal Structural Equation Modeling Chapter Mplus Examples

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    Mplus output files for data examples presented in Geiser, C., Hintz, F. A., Burns, G. L., & Servera, M. (in preparation). Longitudinal structural equation modeling of personality data. In J. F. Rauthmann (Ed.), Handbook of personality dynamics and processes. Elsevier

    Geiser et al. Multitrait-Multimethod-Multioccasion Modeling Chapter Mplus Examples

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    Mplus output files for data examples presented in Geiser, C., Hintz, F. A., Burns, G. L., & Servera, M. (in press). Multitrait-multimethod-multioccasion modeling of personality data. In J. F. Rauthmann (Ed.), Handbook of personality dynamics and processes. Elsevier

    Prionocerus championi Geiser, 2010, n. sp.

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    Prionocerus championi n. sp. Holotype 3: "W Sumatra, Padang env., 200–500 m, S. Jakl lgt., IV. 1995 "; NHMB. Paratypes (1 3 ): 1 3: same data as the holotype (NHMB). Type locality: Padang, Sumatra, Indonesia. Measurements 3 (n = 2): TBL 9.9–10.7 mm, L-h 8.4 –9.0 mm HL 1.5–1.7 mm, PL 1.7–1.8 mm, EL 6.7–7.2 mm Differential diagnosis: Very similar in coloration to P. m a l a y s i a c u s and P. opacipennis, distinguished mainly by the shape of the aedeagus and the last abdominal sternite in males, but also easily recognizable by antennal shape. Elytra and pronotum slightly more slender than in P. coeruleipennis. Body size smaller than in P. wittmeri. Easily distinguished from P. b i c o l o r, P. paiensis and P. viridiflavus by coloration. Description: Habitus as in fig. 40 (3). Body metallic dark blue, partly with greenish lustre. Pronotum bright reddish orange. Elytra metallic dark green, in a small area at the base and around the shoulder, as well as the scutellum metallic blue. Antennae black, with the last segment reddish brown and the first three segments lighter reddish and a bluish black stripe on the dorsal surface. Maxillary and labial palpi mostly reddish brown, parts of each segment infuscate to almost black. Outer edge of labrum yellowish brown. Legs dark bluish black, claws reddish brown. Head behind the eyes about half as wide than the middle part of the pronotum. Vertex not very shining, sparsely and very finely punctate. Frons between eyes sparsely punctate, at its narrowest part about half as broad as the length of the first antennal joint (males); in front of the eyes depressed and slightly rugose. Clypeus almost rectangular, broader than long, slightly shagreened. Labrum about as long as wide, rather flat and more coarsely punctate then the head, with wrinkly microsculpture and some longer blackish setae. Male antennae reaching the first quarter of the elytra in length, until slightly after the humeral callus. First three segments subfiliform (basal one slightly incrassate), segments 4 and 5 slightly widened and flattened, 6– 10 of subtriangular shape, gradually more strongly widened and flattened. Last segment robust, not conspicuously widened, but clearly emarginate. First segment long, second very short, less than one third as long, third to fifth again long, although not quite as the first, sixth to tenth slightly decreasing in length, but increasing in width, the last segment longest, about one third longer than the first. Pronotum slightly longer than broad, widest around the middle, maximal length: maximal width 1: 0.95; subhexagonal, all angles rounded, hind angles approximately 100 °; all pronotal margins distinctly bordered, broadly and conspicuously around hind angles, narrowly at the front margin; basal half shallowly, obliquely impressed at both sides of the disc, part around hind angles slightly convex; shining and without any microsculpture; basal half with some yellowish, suberect pubescence, while the sparse hairs on the fore half are more blackish; the outer margin bearing few longer, black, hair-like setae. Elytra almost exactly fitting the description of P. opacipennis above, apical half slightly less flattened, punctures slightly deeper and a bit less dense and rugose in the basal area. Scutellum like in P. coeruleipennis. Femora slightly metallic, with fine punctures and short blackish hairs and setae. Tibiae also slightly metallic, covered with blackish setae. Tarsi not metallic, with blackish or brownish setae. Abdomen with rather long, sparse, greyish, recumbent pubescence and some longer black, suberect setae; with rather sparse, shallow punctures and somewhat rugose texture. Male: Last abdominal sternite larger, especially longer, than in all the preceding species, basal half of almost cylindrical shape, apical half nearly semicircular (fig. 27). Basal margin rather deeply emarginate, in the middle with almost triangular incision (although the angle is still rounded). The apical margin deeply incised, deeper than in P. coeruleipennis, the opening large and of subtriangular shape with rounded angles. The last tergite very shallowly, inconspicuously emarginate. Aedeagus (figs. 5, 12, 19): Process of phallobase straight; the whole phallobase strongly curved and bent downwards to an angle of about 90 ° (in relation to the apex of the parameres). Parameres (lateral view) after the base very thick (more than double as broad as in P. coeruleipennis), then with a very conspicuous semicircular emargination, bearing some long, brownish hairs along its edge; after the emargination again thickened, drawn into an almost spoon-shaped tip, with some minute teeth around the inner edge of the apex. Seen in dorsal view, the parameres are narrow, largely gaping, slightly curved and never parallel as in P. coeruleipennis and relatives. Median lobe rather robust, with its basal part strongly curved (about 90 °), then not straight but slightly sinuate, apical part not abruptly flattened and without dorsal hook. In dorsal view with very elongate, subparallel ostium, whose hind end is not clearly delimited; after the ostium narrowed and with a long, parallel-sided tip with a very fine central furrow. Sexual dimorphism: Unknown, there were no females available. Variability: Unknown, the available material is too limited. Distribution (fig. 45): So far known only from the type locality in West Sumatra, Indonesia. Probably endemic to this island. Derivatio nominis: Named in honour of the famous British entomologist George Charles Champion (1851–1927), author of the most important and most useful work on Prionoceridae ever published (Champion 1919).Published as part of Geiser, Michael, 2010, Studies on Prionoceridae (Coleoptera: Cleroidea). II. A revision of the genus Prionocerus Perty, 1831, pp. 1-48 in Zootaxa 2328 on pages 36-37, DOI: 10.5281/zenodo.19309

    Peltariosilis major Biffi & Geiser 2020, sp. nov.

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    <i>Peltariosilis major</i> sp. nov. <p> <b>(Figs. 4 E-H, 5F, 10F, 12F, 13C, 14C, 15I-L)</b></p> <p> <b>Type series:</b> HOLOTYPE ♂ (INPA):“ BRASIL, Amapá, Serra do Navio, / Estrada Lagoa Azul, / 0˚52′52″N–51˚58′49″W, / Varredura, 18.iv.2014, J. T. / Câmara, A. Plant & J.A. Rafael // Peltariosilis / n. sp. / det. M. Geiser 2018” (Fig. 5F).</p> <p> <b>Diagnosis:</b> Pronotum with laterobasal lobe flattened, apex curved downwards, with acute lateral spine; dorsal projections very small, sharp, distal margins sinuous, with acute lateral apex acute, pointing posteriorly; scutellar projection lamellar, long, triangular, nearly symmetrical, regularly narrowing apically. <i>Peltariosilis major</i> sp. nov. differs from all other species by the very small dorsal projections of pronotum and by laterobasal lobes flattened dorsally with apex acute curved downwards.</p> <p> <b>Description:</b> Head mostly black, slightly lighter at anterior margin of clypeus; maxillae and labium testaceous yellow; mandibles light brown, darker apically; antennae mostly black, antennomeres I-II orange brown, X-XI dark brown; pronotum and scutellum light orange brown, slightly translucent; elytra dark brown, lighter at lateral margins; legs light orange brown; thorax and abdomen dark brown.</p> <p> <b>Male:</b> (Fig. 5F): Antennae short; antennomere I elongate, slightly wider apically,II short, cylindrical,III-VIII nearly fusiform,slightly swollen,IX-XI slender.Pronotum (Fig.10F): anterior margin broadly arched, continuous with frontolateral lobes; laterobasal lobe with one small acute lateral spine, dorsal surface flattened, posterior margin sharp, oblique, apex acute, strongly curved downwards; dorsal projections very small, posterior margin sharp, sinuous, with small acute lateral spine pointing posteriorly. Scutellum (Fig. 12F) with a long, nearly symmetrical, triangular lamellar projection, regularly narrowing apically. Elytra nearly parallel,slightly wider posteriorly;apex truncate. Abdominal tergite VIII (Fig. 13C) very broad, trapezoidal, lateral margins broadly rounded, wider medially; glandular pores not protruding; distal margin concave, with a small, shallow rounded median notch. Ventrite VII (Fig. 14C) wide, lateral margins slightly convergent posteriorly, wider anteriorly; posterior margin arched; internal margins of median incision nearly parallel, halves broadly separated. Aedeagus (Fig. 15 I-L): ventral plaque of tegmen lateroventral, as long as internal sac, flattened laterally, broad, apex oblique with an acute dorsal pointing tip; parameres fused at base and broadly divergent apically and curved dorsally, apex rounded with small tip pointing dorsally; median lobe membranous, translucent; internal sac tubular, very elongate, slightly curved dorsally, moderately sclerotised, apex membranous; one pair of median dorsal sclerites sinuous, divergent at base than convergent at apex,apex acute, slightly curved ventrally; one pair of short, acute, sclerotised lateral sclerites; paramedian dorsal sclerites elongate, slightly curved internally narrowing at apex, flanking median dorsal sclerites; ventral sclerites not flanking internal sac, parallel to dorsal sclerites and paramedian dorsal sclerites, very elongated, slender, sinuous, curved internally, apex acute, convergent, directed ventrally.</p> <p> <b>Female:</b> Unknown.</p> <p> <b>Etymology:</b> The specific epithet <i>major</i> (Latin for“larger”) refers to the larger size of the species in comparison with the others.</p> <p> <b>Distribution:</b> Brazil (Amapá state) (Fig. 18).</p>Published as part of <i>Biffi, Gabriel & Geiser, Michael, 2020, A revision of Peltariosilis Wittmer (Coleoptera: Cantharidae), a surprisingly diverse Amazonian radiation, pp. 1-26 in Papéis Avulsos de Zoologia (Pap. Avulsos Zool., S. Paulo) (Pap. Avulsos Zool., S. Paulo) 60 (16)</i> on pages 7-9, DOI: 10.11606/1807-0205/2020.60.special-issue.16, <a href="http://zenodo.org/record/4984973">http://zenodo.org/record/4984973</a&gt

    Discodon lineaticorne Biffi & Geiser 2022, sp. nov.

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    Discodon lineaticorne sp. nov. urn:lsid:zoobank.org:act: 66D5B02D-DAD1-47BB-A93E-0981BECD4BB7 Figs 3C, 6E, P, 7E, 8E, 9E, 10E, 12A–C, 15E Diagnosis Differs from other species in the region by the entirely black antennae (Fig. 3C), the males with antennomeres IX–XI with short longitudinal lines dorsally (Fig. 6E), ventrite VII with apices truncate (Fig. 10E), aedeagus (Fig. 12A–C) with three distal projections on distal margin of tegmen, the central projection very long and curved ventrally; females with last ventrite (VII) (Fig. 15E) broadly rounded with a pair of acute projections medially. Etymology The epithet lineaticorne refers to the longitudinal antennal lines on antennomeres IX–XI of the males. Type material Holotype BRAZIL • ♂; São Paulo, Pindamonhangaba, Eugênio Lefèvre; 28 Sep. 1962; Exp. Dep. Zool leg.; MZSP 46436 (Fig. 3C). Paratypes (10 specimens) BRAZIL • 1 ♀; Minas Gerais, Itamonte, Instituto Alto Montana; 22º21′13″ S, 44º47′57″ W, 5–6 Nov. 2019; UC. Entomologia UNIFESP leg.; Malaise; MZSP 46444 • 1 ♀; São Paulo, Campos do Jordão; 22º40′51.4″ S, 45º35′30.5″ W; 1461 m a.s.l.; Oct.–Nov. 2019; S.P. Rosa leg.; MZSP 46445 • 1 ♂; same collection data as for preceding; 1–13 Oct. 2018; MZSP 46446 • 1 ♀; same collection data as for holotype; DZUP 320982 • 1 ♂; same collection data as for preceding; 26 Oct. 1962; MZSP 46438 • 1 ♀; same collection data as for preceding; 1200 m a.s.l.; 21 Dec. 1962; MZSP 46439 • 1 ♂, 3 ♀♀; São Paulo, Ipiranga; Oct. 1908; Luederwaldt leg. ‘20371’ [Luederwaldt’s collection record]; MZSP 46440 to 46443. Description Body length: 13.0– 14.3 mm. Coloration (Fig. 3C): head pitch black, lustrous, except in lateral corners of clypeus, light brown; mandibles light brown, darker at base and tip; maxillary and labial palpi dark brown to black, light brown at apex of last palpomeres; antennae entirely black. Pronotum (Figs 7E, 8E) lustrous, partly translucent, with broad irregular black band from anterior to posterior margin, wider anteriorly and near posterior margin, and narrower near anterior half; from median band, a pair of diagonal black bands; background pale yellow to light orange with barely defined orange patches. Scutellum and elytra pitch black, slightly lustrous; at mid-length of each elytron, large whitish to pale yellow round spot nearly reaching lateral borders but not meeting at suture. Thorax, legs and abdomen dark brown to black, tarsal claws brown. Male (Fig. 3C) Head short, nearly as long as wide, excluding eyes; integument smooth, densely covered with short and fine yellow setae; frons short, vertex flat, occipital region convex, broadly rounded behind eyes. Clypeus flat, anterior margin emarginate, slightly projected anteriorly with median incision. Eyes large, rounded, prominent. Mandibles falciform, acute, without accessory teeth. Last maxillary and labial palpomeres securiform. Antennae (Fig. 6E) long, slightly flattened dorsoventrally; antennomeres III– IX wider distally, sub-serrate; antennomeres IX–XI with short longitudinal lines dorsally. Pronotum (Fig. 7E) wide, about 1.5 times as wide as long; usually, anterior margin slightly arched, almost straight in middle, anterior angles arched; lateral margins slightly sinuate, with shallow notch at posterior third; anterior, posterior and lateral margins elevated; integument smooth, densely covered with very fine yellow setae. Elytra long, each elytron 5 times as long as wide, almost parallel; integument coriaceous, densely covered with short and fine decumbent setae, and much longer thick erect setae. Legs slender, densely pubescent, covered with long and thick setae; tarsi flattened dorsoventrally, fourth tarsomere with transversal slit at base; anterior prothoracic tarsal claws (Fig. 9E) broadly lobed basally, lobe with rounded margin; posterior claws on meso- and metathoracic tarsal claws apparently split at apex, with fine protruding tooth slightly shorter than claws. Abdomen weakly sclerotised, coriaceous, densely covered with long setae; ventrite VI deeply notched at posterior margin, V-shaped, lateral apices arched; ventrite VII (Fig. 10E) with parallel-sided lobes, distal margins truncate; ventrite lobes concave, internal margins directed ventrally.Aedeagus (Fig. 12A–C): ventral wall of tegmen long and broad, apical margin convergent, forming a pair of lateral projections with truncate apices and very long central projection, strongly curved ventrally and with hook-like apex, usually visible between lobes of ventrite VII; fringe of long setae along lateral margins of tegmen dorsally; parameres robust, long and broad, parallel, apex acute; median lobe short, membranous, partially retracted behind parameres. Female Similar to male; antennae (Fig. 6) shorter, without longitudinal lines; pronotum wider, 1.6 times as wide as long, lateral margins without notches; tarsal claws without basal lobe or apical slit; ventrite VI not notched, distal margin slightly arched, concave; ventrite VII broad, lateral and distal margins broadly arched, distal margin with two long apical lobes projecting posteriorly at middle and U-shaped medial notch. Distribution Brazil (Minas Gerais and São Paulo states) (Fig. 16).Published as part of Biffi, Gabriel & Geiser, Michael, 2022, A revision of Discodon tricolor (Guérin-Méneville) and its mimics from the Atlantic forests of Brazil (Coleoptera: Cantharidae), pp. 148-189 in European Journal of Taxonomy 834 (1) on pages 161-163, DOI: 10.5852/ejt.2022.834.1907, http://zenodo.org/record/701767

    Enhanced anti-tumor effects with microencapsulated c-myc antisense oligonucleotide.

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    A phosphorothioate c-myc antisense oligonucleotide was complexed with zinc and encapsulated into injectable biodegradable microspheres. The efficacy of this novel formulation was compared with intravenous administration of the unencapsulated drug in human melanoma and leukemia xenografts in immunocompromised mice. The microencapsulated formulation was more effective as shown by reduced tumor growth, a decreased number of metastases, reduced c-myc expression, and increased survival in the melanoma model, and decreased metastatic potential and increased survival in the leukemia model. These results show that, as has been demonstrated previously with protein and peptide drugs, greater therapeutic efficacy can be obtained when antisense oligonucleotides are delivered from sustained-release formulation
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