1,721,210 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Longitudinal Study of Problem Behavior in Children with Neurofibromatosis-1

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    Longitudinal Study of Problem Behavior in Children with Neurofibromatosis-1 Geethika Pillai, Kristin Lee, Brianna D. Yund, Bonita P. Klein-Tasman Neurofibromatosis type 1 (NF1) is a neurocutaneous condition that can potentially affect the brain, spinal cord, nerves and skin. Children with NF1 often have more difficulties with social-emotional functioning than typically developing children. Previous studies have suggested that school-aged children with NF1 have more problem behaviors than typically developing children. However, studies examining preschool-aged children with NF1 have found similar levels of problem behavior as same-aged peers. Currently there are no longitudinal studies of problem behaviors in children with NF1, which may help us to better understand changes in problem behaviors over time. In the current study, a longitudinal examination of problem behaviors will be conducted to evaluate changes in problem behaviors from early childhood (ages 3-7) to the school-aged years (ages 9-13). The Behavior Assessment System for Children, Second Edition (BASC-2) was completed by parents to assess problem behaviors. The Internalizing, Externalizing and Total Problems scales on the BASC-2 were analyzed for 26 children at both time points. To examine changes over time, correlational tests and paired samples t-test will be performed. Based on previous research, increased problem behaviors from the preschool to the school-age years are expected. Further understanding of problem behaviors in children with NF1 is vital as previous studies have indicated that children with NF1 who have greater internalizing and externalizing problems also have an increased risk of difficulties in school and poorer adaptive functioning

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    Determining and differentiating protein-biopolymer interactions

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    The goal of my research is to understand how proteins selectively bind biopolymers. This problem is closely examined by quantitative modeling of the readout mechanism of protein binding to DNA, determining the specific DNA sequences recognized by transmembrane receptors and resolving the effect of enzymes on polysaccharides. I have developed both computational and experimental tools that identify various factors governing the protein- biopolymer interactions. Below, I list the major projects that I worked on during the course of my PhD. Promoter engineering aims at defining gene expression patterns, which in turn define the behavior of the cells. To date, promoter engineering has been done by trail and error methods experimentally, which is labor intensive and makes it difficult to identify the controlling parameters. Hence it is important to resort to more robust computational methods to make the process less probabilistic. In the past, several computational models have tried to characterize the promoter functionality and strength based on the sequence of the core binding regions (-10, -35, extended -10, discriminator region), but have not been successful. This leads us to believe that various other factors are involved in characterizing the promoter activity. In this work, we try to uncover the importance of shape features and flanking regions in differentiating the functionality of the promoter regions. We used the experimentally determined promoters regions of σ70 and σ 38 holoenzyme as our database. This work has important applications for promoter design in bacterial genome engineering. Chapters 1-4 talk about the work done on this project. Algal bioenergy systems are the future of the bio fuel industry. They promise several advantages over terrestrial biomass – faster growth rates, no land issues, avoid freshwater usage etc. However, the major obstacle in using macro-algae as an everyday fuel lies in the limited knowledge regarding the enzymatic degradation of its major sugars – Alginate and Laminarin by alginate lyases and laminarinases respectively. My work focuses on overcoming this limitation by characterizing several alginate lyases and laminarinases from 3 different bacteria (Vibrio splendidus 12B01, Vibrio splendidus 13B01 and Vibrio breoganii IC10) to develop a concoction of lyases by determining their general working conditions, effectiveness of working, mode of action and hence understanding the specific roles of each lyase in the breakdown pipeline of the sugars. Work done on this project is written in Chapters 5-9. Chemotaxis is a primitive behavioral system by which bacteria travel towards better environments. It is a well-studied mechanism in the model organism Bacillus subtilis (B.subtilis) that can perform chemotaxis towards 20 L-amino acids normally found in proteins. Recently in our lab, we found concrete evidence that B.subtilis also undergoes DNA taxis, i.e, movement in response to DNA gradient. We determined the receptor McpC to be responsible for this phenomenon. SELEX experiments are carried out to determine the McpC binding motif in B.subtilis. However, the major challenge lies in processing the millions of reads produced by SELEX, resolving the low quality reads and data integration of the filtered high quality reads. My work focuses on developing computational models to overcome this challenge and hence determining the McpC binding site. Chapters 10-11 talk about the work done on this project.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2019-12-01The student, Geethika Yalamanchili, accepted the attached license on 2017-12-06 at 00:02.The student, Geethika Yalamanchili, submitted this Dissertation for approval on 2017-12-06 at 00:08.This Dissertation was approved for publication on 2017-12-08 at 10:59.DSpace SAF Submission Ingestion Package generated from Vireo submission #11878 on 2018-03-13 at 10:37:44Made available in DSpace on 2018-03-13T17:35:50Z (GMT). No. of bitstreams: 2 YALAMANCHILI-DISSERTATION-2017.pdf: 6910988 bytes, checksum: e976d4638b90751f8b3c8263fd3f5fb7 (MD5) LICENSE.txt: 4218 bytes, checksum: 33a02671d0218531b02d44bbbd4b0aaa (MD5) Previous issue date: 2017-12-08Embargo set by: Seth Robbins for item 105485 Lift date: 2020-03-13T17:36:05Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 105485 on 2020-03-14T09:15:31Z

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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