3,261 research outputs found
DIFFERENT BONE SENSITIVITY TO MALFORMATIONS INDUCED BY PROCARBAZINE IN FETAL RATS
No full textThe study aimed at to induce cleft-lip-alveolus-palate (CLAP) applying procarbazine in rat fetuses at the 14(th) day of pregnancy, to supply thiocyanate and/or folic acid Sufficient for preventive treatment and Subsequently to investigate cleft extent in the palatal area as well as boric Maturity. In this animal model, female primiparous inbred rats (LEW.IA) Were used. The gravid animal were separated into treatment groups: group K (Control), group P (procarbazine), group TP (thiocyanate and procarbazine) and group FTP (folic acid, thiocyanate, procarbazine). The results reveal that procarbazine may induce clefts in the palate area. Clefts Occurred most frequently in group TP and mainly comprised subtotal clefts of the posterior secondary palate. As for palatal length, group FTP displayed the longest palate which was significantly different only from group K. A different picture was shown for the secondary palate with group TP displaying the shortest Values which were significantly different from those in groups K, P, and FTR Thus, group TP showed the most marked negative changes both for cleft frequency arid palatal length as compared to group K and the other groups. The preventive application of either thiocyanate (TP) or thiocaynate and folic acid combined (group FTP) failed to completely prevent cleft formation in the palate area. In conclusion, a preventive effect on palatal clefts arid growth inhibition Could not be proved for the vitaminoid thiocyanate
DIFFERENT BONE SENSITIVITY TO MALFORMATIONS INDUCED BY PROCARBAZINE IN FETAL RATS
No full textThe study aimed at to induce cleft-lip-alveolus-palate (CLAP) applying procarbazine in rat fetuses at the 14(th) day of pregnancy, to supply thiocyanate and/or folic acid Sufficient for preventive treatment and Subsequently to investigate cleft extent in the palatal area as well as boric Maturity. In this animal model, female primiparous inbred rats (LEW.IA) Were used. The gravid animal were separated into treatment groups: group K (Control), group P (procarbazine), group TP (thiocyanate and procarbazine) and group FTP (folic acid, thiocyanate, procarbazine). The results reveal that procarbazine may induce clefts in the palate area. Clefts Occurred most frequently in group TP and mainly comprised subtotal clefts of the posterior secondary palate. As for palatal length, group FTP displayed the longest palate which was significantly different only from group K. A different picture was shown for the secondary palate with group TP displaying the shortest Values which were significantly different from those in groups K, P, and FTR Thus, group TP showed the most marked negative changes both for cleft frequency arid palatal length as compared to group K and the other groups. The preventive application of either thiocyanate (TP) or thiocaynate and folic acid combined (group FTP) failed to completely prevent cleft formation in the palate area. In conclusion, a preventive effect on palatal clefts arid growth inhibition Could not be proved for the vitaminoid thiocyanate
Effects of centric relation prematurities of the frontal teeth
No full textCentric relation prematurities of frontal teeth are frequently found with patients who have severe orthodontic anomalies or received extensive restorative treatment. They can cause a range of symptoms ranging from Loosening of the teeth to temporomandibular disorders (TMD). The objective of this work has been to derive a mathematical description of the mandibular and periodontal forces generated by anterior prematurities for different incisor relations. In order to quantify the effect of contact area (location and inclination) and the tooth inclination, a two-dimensional mathematical approach was used. Vectorisation of the forces and bending moments makes it possible to predict under which conditions the load increase mainly affecting the anterior teeth can and may cause localized pain and eventually Loosening and flaring/crowding of the upper/lower incisors and under which conditions the temporomandibular joint wilt suffer a large increase in retrusive force, which potentially Leads to TMD. For 10 patients with anterior prematurities, analysis of the incisor relation was carried out. For all cases the conclusions drawn from the mathematical model were in full agreement with the reported symptoms, which could be successfully treated. (C) 2007 Elsevier GmbH. All rights reserved
Functional state of the mandible and rolling-gliding characteristics in the TMJ
No full textFor the physiological intact stomatognathic system, the three main functional states (occlusal articular functions, free mandibular movements, and ideal. bolus function) were biomechanically discussed concerning the structure of movement, rolling-gliding characteristics, and force transfer in the temporomandibular joint (TMJ). In all three cases, rolling is not possible in the TMJ since the instantaneous rotational axis is positioned outside of the joint - rolling is not necessary because the TMJ is not loaded by appreciable forces. In the aged stomatognathic system with a lost discus and considerable Loads in the TMJ, however, the attrition of the joint is eased by rolling movement at the articulating surfaces. The destruction of the discus can be seen as a physiological adaptation which brings back the joint to an original odontogen condition. (C) 2007 Elsevier GmbH. All rights reserved
Producción musical del tema Dónde Estás del artista Tomas Cansing
No full textThe musical theme “Dónde Estás” came in a spontaneous way, back in August of 2013, based on personal experiences of the author. The project was totally produced by the musician and composer Tomas Cansing, who tried to capture his ideas and both musical and lyrical experiences, to attempt that the listener feels identified with the principal concept of the song. Due to the musical features of the song, the production process was carried out by implementing standardized concepts and techniques related to the musical trend of this project. At the same time taking into account the musical references exposed by the artist, since there were some elements as: instrumentation and sonority that worked as a base for the musical production…El tema musical “Dónde Estás” nace de manera espontánea, a mediados del mes de Agosto del 2013, basado en experiencias propias del autor. El proyecto fue producido en su totalidad por el músico y compositor “Tomas Cansing”, quien intentó plasmar sus ideas y vivencias tanto en música como en letra, procurando que el oyente se sienta identificado con el concepto principal de la canción. Debido a las características musicales de la canción, el proceso de producción se llevó a cabo implementando los conceptos y las técnicas estandarizadas en relación al género musical del correspondiente proyecto. A su vez, se tomó en consideración las referencias musicales expuestas por el artista, ya que existieron elementos tales como: instrumentación y sonoridad que sirvieron como base para la producción musical…
TOMAS: De variant op palen
No full textTOMAS is een bouwmethode voor de geïndustrialiseerde aanleg van een tunnelbak voor spoor- en wegverbindingen onder maaiveld. Dit rapport is globaal onder te verdelen in drie onderwerpen: 1) Beschrijving van de technologie; In dit gedeelte van het rapport wordt kort ingegaan op het technische idee achter TOMAS. De knelpunten worden behandeld en technisch onderbouwd. Bij een optimale werking van het proces kan TOMAS een voortgangssnelheid boeken van 45 meter per dag. 2) Krachtsbepaling onder een maatgevende treinlast in eindfase; Uitgangspunt is dat TOMAS een eindprodukt achterlaat dat geschikt is om treinverkeer toe te laten. Er wordt een belastinggeval bekeken waarbij twee treinen elkaar passeren en een statische belasting geven van 160 kN/m. Het blijkt dat de lengte van de treinen invloed hebben op de momentverdeling in de bak. Een maximum moment (circa 12.000 kNm) wordt bereikt bij een treinlengte van 30 meter. Het moment veroorzaakt een vormverandering in de bak waardoor de voegen neigen open te gaan staan. Als de voegen open staan kan grondwater in de bak stromen. Een eis voor de uiteindelijke constructie is dat deze grondwaterdicht moet zijn. Om de bak onder deze last waterdicht te houden is een axiale voorspanning benodigd van 3200 kN. De parameters benodigd voor de berekening, de beddingsconstante, de h.o.h. afstand van de heipalen en de veerstijfheid van de palen is bepaald in een typisch Rotterdams grondprofiel. 3) Technische onderbouwing van de haa/baarheid van TOMAS in de bouwfase; In de bouwfase is voornamelijk de invloed van de uitsleuver belicht waarbij is geprobeerd antwoord te krijgen op de volgende vragen: \u95 Blijft het graaffront stabiel, zal de grond niet gaan afschuiven? Wat is de invloed van gekruiste platen (frietsnijdervorm) aan het graaffront op de stabiliteit van het graaffront? \u95 Is er een blijvende axiale voorspanning in de bak? \u95 Hoe groot zijn de vijzelkrachten wanneer de uitsleuver zich door de grond drukt? \u95 Hoe reageert de betonnen bak onder de, niet continue, vijzelkracht? Om het graaffront van de uitsleuver zo klein mogelijk te houden wordt de grond aan het front gestabiliseerd met gekruiste platen. Deze platen hebben de vorm van een 'frietsnijder' en worden met kracht door de grond gedrukt. Deze kracht is erg afhankelijk van de grondsoort. Over het algemeen geeft, bij het gebruik van overlangse platen aan het graaffront, een zandige grondsoort grote krachten (tot 50.000 kN), wat het gebruik van deze platen aan het graaffront minder geschikt maakt voor deze gronden. Voor kleiige gronden ligt de vijzelkracht in de orde van grootte 20.000 kN.Hydraulic EngineeringCivil Engineering and Geoscience
Identifying Author Fingerprints in Texts via Graph Neural Networks
No full textThe world is generating more and more network data in many different areas (e.g., sensor networks, social networks and even text). A unique characteristic of these data is the coupling between data values and underlying irregular structure on which these values are defined. Thus, researchers developed Graph Neural Networks (GNNs) to use deep learning approaches on these irregular network data. GNNs developers tried to replicate the recent success of Convolutional Neural Networks (CNNs) and developed its graph counterpart Graph Convolutional Neural Network (GCNN) and more different variations of GNNs (e.g. EdgeNet). However, all these architectures are relatively young, and the impact of different parameters to classification result is not well researched compared to regular neural network architectures. To address this issue, we propose to use authorship attribution problem to research the impact of different architectures and their variations to classification accuracy and how GNNs can be used to improve on authorship attribution task compared to the baseline architectures. Explicitly, we define the dataset which is going to be used throughout the experiments and the method to convert text excerpts of authors into the network that can be classified with GNNs (called WAN). WAN is as a network that captures unique author fingerprint. We also define the set of GNN architectures (and different combinations and variations of them), baseline architecture (SVM) and experiments that are used with those architectures. This experiment setting allows us to compare different GNN architectures among themselves and the baseline architecture. Also, we define a method to reduce the dimensions of author fingerprints (WANs) and use these sparse author fingerprints for the same experiments with the same architectures. Numerical results show the improvement over the baseline architectures in nearly all defined experiments. Also, we found that more complex GNN architectures (e.g. EdgeNets) are superior to shallower architectures with more laborious experiments (e.g. classification by gender). More complex architectures also require hyperparameter re-tuning in order to achieve optimal results. Furthermore, experiments with sparse author fingerprints showed that we could achieve comparable results to standard fingerprints with faster training times and significantly reduced dimensions. GNN architectures used with sparse author fingerprints were usually superior to baseline architectures
The Authorship of Tomas Espedal
No full textThis thesis is centered around the norwegian author Tomas Espedal. The paper sets out to read Espedal’s novels as one text altogether with the same I, while exploring how the literary term autofiction supports this approach. The thesis is divided into three parts. The first part of the thesis examines the genre autofiction. It shows examples of how autofiction is used as a genre for different generations of authors, and how it is popular to write this hybrid genre between autobiography and fiction. It illuminates a tendency to writeautofiction, discussing the ethical questions that arises when the written books become a mix of autobiography and fiction. This is further discussed in the third part. The second part of the paper probes how the I develops throughout the books, and how the author writes about the themes love and alcohol. Both themes are literary fuel to the author, both in his writing and in his performances. I choose to understand the paratexts - interviews and performances - as complementary dimensions of the same I that appears in the novels. As life and literature become fused, I argue that it is pointless to separate the two.In third part of the thesis, I show how writers write about each other and interact with each others’ lives and literary works. While the main focus is Tomas Espedal’s authorship, the thesis also discusses Karl Ove Knausgård’s works as well as upcoming authors and authors who made an impact in the danish public with their books. I use interviews, talks and tv-shows to let Tomas Espedal discuss his own writing. Finally, I discuss the ongoing challenges for autofiction and give my own suggestion to how the authorship may evolve in the future when the next books in the one great collected Tomas Espedal novel will be written. <br/
TOMAS KATRIDARIĆ - DER DRUCKER UND DOMHERR AUS SENJ
No full textAutor donosi nekoliko novih arhivskih podataka o Tomi Katridariću, svećeniku i senjskom kanoniku. T. Katridarić je jedan od djelatnika u drugom razdoblju (1507. i 1508. godine) senjske tiskare. Tomas Katridarić, uz svećeničke službe i obaveze bio je aktivni sudionik u javnom i društvenom životu grada Senja i Monarhije.The author writes about some new archival data about Tomas Katridarić, the priest and Senj canon. Tomas Katridarić was one of the workers in the long period (1507 and 1508) of the Senj printing shop. Tomas Katridarić was an active member of public and social life of Senj and the monarchy alongside his service as a priest.Der Autor bringt einige neue Archivdaten über Tomas Katridarić, dem Pfarrer und dem Domherrn aus Senj. Tomas Katridarić ist einer von den Arbeitern aus dem zweiten Zeitabschnitt (1507 und 1508 Jahr) der Druckerei aus Senj. Toma Katridarić war, neben dem Pfarrdienst und den Verpflichtungen, ein aktiver Teilnehmer im Öffentlichen- und Gesellschaftsleben der Stadt Senj und der Monarchie
Changes in insulin like growth factors, myostatin and vascular endothelial growth factor in rat musculus latissimus dorsi by poly 3-hydroxybutyrate implants
No full textThe present study aimed at researching the synergistic effect between an ectopic bone substitute and surrounding muscle tissue. To describe this effect, changes of insulin like growth factors (IGF1, IGF2), myostatin (GDF8) and vascular endothelial growth factor (VEGF) mRNA content of 12 Wistar-King rats musculus latissimus dorsi with implanted poly-3-hydroxybutyrate (PHB) scaffold were examined after 6 and 12 weeks. At each time interval six rats were killed and implants and surrounding tissues prepared for genetic evaluation. Eight rats without any implants served as controls. RNAwas extracted from homogenized muscle tissue and reverse transcribed. Changes in mRNA content were measured by Real-Time PCR using specific primers for IGF1, IGF2, GDF8 and VEGF. Comparing the level of VEGF mRNA in muscle after 6 and 12 weeks to the controls, we could assess a significant increase of VEGF gene expression (
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