4,853 research outputs found
Non-invasive hemodynamic monitoring techniques for detecting Preload responsiveness in critically ill patients
Volume expansion is the first-line treatment for acute circulatory failure in almost all cases. However, its inconsistent effectiveness and its side effects make it necessary to predict the effects before undertaking it. Several tests have been developed to detect this state of preload dependence, and we are interested in refining some of them and improve their use. The end expiratory occlusion (EEXPO) test consists in transiently stopping mechanical ventilation at end expiration to increase venous return and, thus, cardiac preload. In preload responder patients it is expected to increase cardiac output. We have gathered an amount of information from the existing literature, showing that its ability of detecting fluid responsiveness is very high, through a systematic review and meta-analysis. The effects of this test must be assessed on cardiac output, and several methods have already been described for this. Bioreactance is a completely non invasive technique to measure cardiac output, which has been demonstrated to be reliable in detecting preload responsiveness through a passive leg raising (PLR) maneuver. Nevertheless, its role in detecting a positive EEXPO test was never investigated. In the main study of this PhD project, we show that the current available commercial version of the bioreactance device is not
suitable for this purpose, due to its very long averaging and refreshing times (24 and 4 seconds, respectively). However, when we used a research version of the device, which allowed us to reduce both intervals (8 and 1 second for averaging and refreshing times, respectively), bioreactance proved to be a reliable method to detect preload responsiveness through the EEXPO test. We have also described an original and reliable method for measuring the effects of both PLR and EEXPO tests, which consists of measuring the perfusion index (PI), the ratio between the pulsatile and the non-pulsatile portion of the pulse oxygen saturation signal. Although the signal could not be collected stably in all patients, changes in this index during passive leg raising were able to measure the effects of the PLR test and predict the response to volume expansion. Similarly, Pl measurements could identify a positive EEXPO test, even though their changes were of lower amplitude compared to those of a PLR test. Our results open up the possibility of measuring the effects of these tests of preload responsiveness using non-invasive tools. This could prompt their use outside the intensive care unit, such as in the emergency department, where tracking changes of cardiac output during the first hours of the management of acute circulatory failure could lead to a more rational use of fluid administration
Electrokinetic effects across Nafion 120 membranes
The electroosmotic coefficient, and the streaming potential across Nafion 120 membrane separating two uni-univalent electrolyte solutions of the same concentration have been studied. Different electrolytes have been considered, namely NaCl, LiOH, NaOH, KOH and CsOH. According to the non-equilibrium thermodynamic theories the ratio (Δφ/ΔP)/(Jv/I), with (Δφ)(electrical potential)/(gDP)(pressure difference) the streaming potential and Jv(volume flow)/I(electrical current flow) the electroosmotic quantity, approaches the unity
Raccomandazioni sull’uso dei mezzi di contrasto organo-iodati e per Risonanza Magnetica per via iniettiva. Considerazioni radiologiche e medico-legali
Francesco Scorza Barcellona o della passione agiografica
L'autrice traccia, sul filo dei ricordi, il profilo scientifico ed umano di Francesco Scorza Barcellona ed introduce gli studi raccolti nel volume.The author traces, on the thread of memories, the scientific and human profile of Francesco Scorza Barcelona and introduces the studies collected in the book
Delle lodi di don Francesco Medici de' principi di Toscana : orazione /
Engraved t.p. vignette of Medici arms. On recto of 2nd leaf is Callot's full-page engraved port. of Francesco de' Medici, son of Grand Duke Ferdinand I. It is in Lieure's 1st state. The port. also appeared the same year in Alessandro Adimari's Esequie dell' ill.mo & ecc.mo principe don Francesco Medici (Florence : Gio. Donato & Bernardino Giunti); see Lieure. Large woodcut Giunti device on p. [31].Lieure, J. Jacques Callot,Mode of access: Internet.At head of front pastedown is bookplate of Francesco Riccardi de Vernaccia (Florence, ca. 1780; see Gelli, p. 387). Below it is the label of Horatius (Orazio) Landau, with stamped shelfmark 53021. At foot is the bookplate of U. Manganelli, signed with the initials SER. A dedicatory inscription at foot of t.p. has been scratched out.Binding: modern marbled paper, backed in green vellum. Date, author & title writte on spine.Port. trimmed into the image at right margin and foot
Frankenstein
@inproceedings{orsini2015graph,
title={Graph invariant kernels},
author={Orsini, Francesco and Frasconi, Paolo and De Raedt, Luc},
booktitle={IJCAI Proceedings-International Joint Conference on Artificial Intelligence. IJCAI},
year={2015}
Didattica e ricerca. L’esperienza del Laboratorio aragonese e sforzesco
In the workshop on Diplomatic correspondences in the Italian Renaissance, directed in January-May 2018 by Francesco Storti and Francesco Senatore in the Istituto italiano per gli studi filosofici of Naples, 12 undergraduate and graduate students learned to read and trascribe italian diplomatic dispatches of the 15th cent., producing a specimen of scientific edition. In the opinion of the author, such activities and similar ones are very useful for future school teachers and scholars and they could be introduced in the university and pHD courses of history. Students of humanistic sciences should have concrete contacts with the historical research on primary sources. On the other hand, editing of historical sources could become a marginal activity because it is not enough appreciated in the current research evaluation processes.
Keywords: Didattica, edizione documentaria, diplomazia rinascimentale; education, documentary edition, renaissance diplomac
LA MADONNA ESTERHAZY DI RAFFAELLO
LA MADONNA ESTERHÁZY DI RAFFAELLO A PALAZZO MARINO, di Francesco Murano,
Fotografie di Sergio Oriani
Il curatore della mostra, Stefano Zuffi, ha voluto inquadrare criticamente l’opera di Raffaello
proveniente dal Museo di Budapest, ponendola tra la Vergine delle Rocce di Francesco Melzi,
proveniente dall’Istituto delle Suore Orsoline di Milano e la Madonna della Rosa di Giovanni
Antonio Boltraffio, proveniente dal Museo Poldi Pezzoli della stessa città. L’architetto Corrado
Anselmi ha progettato un affascinante allestimento, concependolo come un percorso che si
sviluppa attraverso tre soste utili all’ammirazione delle opere. L’autore Francesco Murano,
spiega con ricchezza di particolari i vincoli del progetto illuminotecnico e le scelte luministiche.Once again, for the Christmas season, the Municipally of Milan decided to display an important work in the frame of the Palazzo Marino’s Alessi Hall. For this year 2014, the choice has been to propose the Estheràzy Madonna by Raphael, from the Museum of Budapest.
The exhibition curator, Stefano Zuffi, wanted to critically frame to work of Raphael by placing it between the Vegine delle Rocce (Virgin of the Rocks) by Francesco Melzi, coming from the Milan’s Istituto delle Suore Orsoline, and the Madonna della Rosa by Giovanni Boltraffio, from the Milanese Museo Poldi Pezzoli.
The Architect Corrado Anselmi designed a fascinating display, convinced as a path that develops through three stops that are useful for the enjoyment of the works.
The author Francesco Murano, explains with many details the lighting design project
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