152 research outputs found
Attention-deficit/hyperactivity-related symptoms among children with enterovirus 71 infection of the central nervous system
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Differentiating and Investigating Acute and Chronic Typologies of Suicidal Patients Using Quantitative and Qualitative Suicide Status Form (SSF) Responses
No full textDegree awarded: Ph.D. Psychology. The Catholic University of AmericaThis dissertation can be viewed by CUA users only.The Suicide Status Form (SSF) was developed by Jobes and colleagues (1997) to provide a standardized, clinically useful multipurpose assessment, treatment, and tracking clinical tool for suicidal patients. Research conducted using the SSF to date has pursued a larger effort within suicidology to study and potentially identify specific typologies of suicidal patents (e.g., chronic vs. acute), who may have uniquely different clinical presentations and responses to treatment. The purpose of this study was to investigate the utility of the two quantitatively derived factor loadings of the "Core SSF Assessment" recently identified by Conrad et al (2009) that differentiated chronic (Factor 1) and acute (Factor 2) styles of responding to the SSF. Following this work, the current study attempted to explore the phenomenological differences between these two different suicidal presentations using qualitative data from three sections from the SSF: (a) the Core SSF Assessment, (b) the qualitative "Reasons for Living vs. Reasons for Dying Assessment," and (c) the qualitative "One Thing" Assessment. In this study, two experts in clinical suicidology classified 97 suicidal inpatients as chronically or acutely suicidal based on demographic, diagnostic, and suicidal attempt history data. This expert sort yielded n=39 individuals classified as chronically suicidal, with n=58 classified as acutely suicidal. Based on this sort, logistic regression analyses were performed using the quantitative rating responses from the Core SSF Assessment to determine if the previously identified two factors from Conrad et al (2009) study were indeed significant predictors of expert rated chronic vs. acute suicidality, respectively. High SSF rating scores on the empirically derived Factor 1 loading were found to significantly predict the expert sorted chronic cases; however SSF rating scores pertaining to the Factor 2 loading did not predict expert sorted acute cases. Additional chi-square statistics demonstrated that interpersonal concerns appeared to be particularly meaningful for both chronically and acutely suicidal individuals, and were observed to contribute to both suicidal states and life-sustaining beliefs. These seemingly contradictory findings raise a paradox for the suicidal individual, where the very relationships that can give an individual reason to live, can also seem to motivate a person towards suicide.Submitted by Shanyun Zhang ([email protected]) on 2013-05-09T17:02:05Z
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Previous issue date: 2010-01-0
Hydrodynamic Study of a Suction Stabilized Float (SSF)
Full text linkabstract: In this work, the hydrodynamics of Suction Stabilization is studied. Suction stabilization was found to stabilize floating platforms/floats in a much better way as compared to the conventional methods. This was achieved by an effective increment in the metacentric height due to the Inverse Slack Tank (IST) effect. The study involves the analysis of the existing designs and optimizing its performance. This research investigates the stability of such floats and the hydrodynamic forces acting on the same for offshore applications, such as wind turbines. A simple mathematical model for the condition of parametric resonance is developed and the results are verified, both analytically and experimentally.Dissertation/ThesisReal time working of SSF in heavy wind and rain conditionsAnimation explaining working of SSFExperiment with patio umbrella mounted on SSFMasters Thesis Mechanical Engineering 201
Simultaneous saccharification and fermentation (SSF) of non-starch polysaccharides and starch from fresh tuber of Canna edulis ker at a high solid content for ethanol production
No full textCanna edulis ker is a potential feedstock for ethanol production because of its low nutrition requirements and the high starch content of its tubers. The processing of C. edulis is limited by the high viscosity of the biomass. In this study, cell wall degrading enzymes (CWDEs) containing acid xylanase and beta-glucanase were successful in reducing the viscosity (from 167.30 Pa s to 8.66 Pa s) at 50 degrees C for 120 min. The effect of CWDEs on simultaneous saccharification and fermentation (SSF) was investigated. Addition of CWDEs before SSF, resulted in an increase in total sugar and fermentable sugar. Meanwhile, the viscosity decreased sharply from approximately 200.00 Pa s to 2.98 Pa s, thereby improving the fermentation parameters and the mass fraction of the theoretical ethanol yield was 94.5%. Only special demand of nutritional ingredients was nitrogen, urea at 750 mg kg (1) was found to be suitable for this purpose. In the verification experiments, the mass fraction of the theoretical ethanol yield in a 5 L fermentor was 98.3%. In conclusion, the pretreatment with CWDEs has significant effect on high level ethanol production using roots and tubers on an industrial scale from the biomass utilization efficiency and economic standpoint. (C) 2013 Elsevier Ltd. All rights reserved
Psychiatric and psychosocial predictors of substance use disorders among adolescents - Longitudinal study
No full text[[abstract]]Background Few studies have prospectively examined psychosocial and psychiatric predictors of adolescent substance use disorders simultaneously. Aims To identify psychosocial and psychiatric predictors of substance use disorders in adolescence. Method School children aged 12 years (s.d.=0.3) free from any substance use disorder at grade 7 (n=428) were assessed in three consecutive years, using a standardised psychiatric interview. Their baseline psychosocial information was also collected. The outcome was the onset age of a substance use disorder. The Cox regression model was used for data analysis. Results The most significant predictive factors for adolescent substance use disorder included male gender, attention-deficit hyperactivity disorder, conduct disorder and sibling use of tobacco. Three protective factors against such morbidity included living in a household with two parents, a good academic grade at grade 7 and objection to the use of substances. Conclusions Early intervention for disruptive behaviour disorders and specific psychosocial risk factors might prevent substance use disorders in early adolescence
All-cause mortality and specific causes of death in autism: A nationwide analysis
No full text[[abstract]]Background: Western studies have reported a higher mortality risk in autistic individuals. However, the specific causes of death and the roles of age, sex, and concurrent intellectual disability (ID) remain unclear. This study aimed to analyze the causes of death in autism and the moderating effects of age, sex, and concurrent ID. Methods: This nationwide population-based study, conducted between 2008 and 2019, identified 64,685 autistic individuals and were age and sex matched with 1,279,174 nonautistic controls. All-cause mortality and specific causes of death were compared between autistic and nonautistic controls. The modifying effects of age, sex, and concurrent ID were also examined. Results: The risk of all-cause mortality (hazard ratio = 2.28) is higher in autistic individuals than in nonautistic controls. The elevated all-cause mortality in autistic individuals was consistent across sex, age, and the presence or absence of ID and was higher in autistic women, adults, and those with concurrent ID than in their counterparts. The mortality risks for most examined specific causes, except cancer, are higher in the autistic group than those in nonautistic controls. Although autistic individuals with concurrent ID showed higher mortality risks in neurological, respiratory, and gastrointestinal categories and accidents, the risk of suicide is lower. Autistic women had higher mortality risks in most categories, whereas autistic adults had a higher mortality risk in the neurological and respiratory categories. Conclusion: Autistic individuals face higher mortality risks across various disease categories, regardless of sex, age, or concurrent ID. Health care policies should prioritize the implementation of specific strategies for the early detection of diseases and health promotion, as well as accident and suicide prevention among autistic women and those without ID. Clinical Trial Registration number: NCT04010422
Association of stroke with the receptor-binding profiles of antipsychotics—A case-crossover study
No full text[[abstract]]Background Previous research suggests a link between antipsychotic use and stroke, but the relationships between receptor-binding profiles of antipsychotics and the risk of cerebrovascular events are unclear. Methods A total of 14,584 patients with incident stroke were enrolled in the National Health Insurance Research Database in Taiwan from 1998 to 2007. We conducted a case-crossover study to compare the rates of antipsychotic use. The effects of receptor-binding profiles of antipsychotics on stroke risk were estimated, while the moderating effects of age, sex, presence of dementia, and duration of antipsychotic treatment were evaluated by stratified analyses. Results The adjusted odds ratio of stroke risk with antipsychotics exposure was 1.60 (95% confidence interval, 1.51–1.69) using a 14-day time window. The use of antipsychotics with a high binding affinity of M1 muscarinic and α2 adrenergic receptors was associated with a greater risk of stroke than the use of other types of antipsychotics. An increased risk of stroke with antipsychotic use was noted in the patients who were older and/or who suffered from dementia. Moreover, our results showed that stroke risk with antipsychotic use was in a dose-related relationship. Conclusions Our findings suggest an association between stroke risk and high M1 muscarinic and α2 adrenergic affinity. The clinical implication is to start antipsychotics treatment at low dosages and to closely monitor the side effects in the initial treatment, particularly for individuals with older age and the presence of dementia
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