1,720,956 research outputs found
Dyskinesia in first-episode schizophrenic patients treated with second generation antipsychotics. Abnormal movements and schizophrenia outcome
Full text linkMolts trastorns del moviment observats en pacients esquizofrènics passen desapercebuts, especialment els de lleu o moderada intensitat o bé els associats amb anosognosia. El valor dels moviments extrapiramidals i específicament de la discinèsia i el parkinsonisme com a factor pronòstic en l'esquizofrènia no és ben conegut. En aquest estudi prospectiu, s'estudia la relació de la discinèsia i altres símptomes extrapiramidals amb l'evolució a un any del trastorn en una cohort de 112 pacients en el seu primer episodi de l'espectre esquizofrènic tractat amb antipsicòtics de segona generació. Els resultats van mostrar que en el model ajustat de regressió lineal, la resposta primerenca al tractament (p = 0.001), l'abús d'alcohol (p = 0.026), el nivell ocupacional més alt aconseguit (p = 0.031), l'edat d'inici més primerenca (p = 0.033), els moviments discinéticos durant les primeres vint i cuatre setmanes (p = 0.034) i el sexe femení (p = 0.039), però no les primeres vuit setmanes de Parkinsonismo, com a variables significatives (R² ajustat 0.416). La direcció de l’associació de les discinèsies amb la severitat de la malatia fou negativa. Trenta-dos pacients van mostrar discinèsia en les primeres vint setmanes i sis pacients van ser diagnosticats com discinèsia tardana durant el seguiment de l'estudi (5.3% de 112 pacients en la mostra inicial, 8.3% dels 72 pacients que van completar el seguiment). Es postula el potencial dels primers moviments discinéticos com una finestra del sistema dopaminèrgic en l'esquizofrèniaMuchos trastornos del movimiento observadas en pacientes esquizofrénicos pasan desapercibidas, especialmente las de leve o moderada intensidad o bien las asociadas con anosognosia. El valor de los movimientos extrapiramidales y específicamente de la discinesia y el parkinsonismo como factor pronóstico en la esquizofrenia no es bien conocido. En este estudio prospectivo, se estudia la relación de la discinesia y otros síntomas extrapiramidales con la evolución a un año del trastorno en una cohorte de 112 pacientes en su primer episodio del espectro esquizofrenico tratado con antipsicóticos de segunda generación. Los resultados mostraron que en el modelo ajustado de regresión lineal la respuesta temprana al tratamiento (p = 0.001), el abuso de alcohol (p = 0.026), el nivel ocupacional más alto alcanzado (p = 0.031), la edad de inicio más temprana (p = 0.033) , los movimientos discinéticos durante las primeras veinticuatro semanas (p = 0.034) y el sexo femenino (p = 0.039), pero no las primeras ocho semanas de Parkinsonismo, como variables significativas (R² ajustado 0.416). La dirección de la asociación de les discinèsies con la severidad de la enfermedad fué negativa. Treinta y dos pacientes mostraron discinesia en las primeras veinticuatro semanas y seis pacientes fueron diagnosticados como discinesia tardía durante el seguimiento del estudio (5.3% de 112 pacientes en la muestra inicial, 8.3% de los 72 pacientes que completaron el seguimiento). Se postula el potencial de los primeros movimientos discinéticos como una ventana del sistema dopaminérgico en la esquizofrenia.Many movement abnormalities observed in schizophrenic patients are neglected, especially those in mild and moderate forms or associated to anosognosia. The role of extrapyramidal movements and specifically dyskinesia and Parkinsonism as prognostic factor in schizophrenia is not well known. In this prospective work the relationship of dyskinesia and other extrapyramidal symptoms with one-year psychiatric outcome was studied in a cohort of 112 patients suffering from First Episode of Schizophrenia Spectrum disorder and treated with Second Generation Antipsychotics. Results showed that, linear regression model of outcome fitted early response (p= 0.001), abuse of alcohol (p= 0.026), higher occupational level reached (p= 0.031), younger age at onset (p= 0.033), dyskinetic movements during the first twenty-four week (p= 0.034) and female sex (p= 0.039), but not first eight weeks Parkinsonism, as significant variables (adjusted R² 0,416). Direction of the association of dyskinesia with severity of illness was negative. Thirty-two patients showed dyskinesia in the first twenty-four weeks and six patients were diagnosed as Tardive Dyskinesia during the follow-up of the study (5.3% out of 112 patients in the initial sample, 8.3% out of the 72 patients that complete the follow-up. The potential role of early dyskinetic movements as a window of the dopaminergic system in schizophrenia is postulated
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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