54 research outputs found
Recombination networks as genetic markers in a human variation study of the Old World
No full textChristina J. Adler, Alan Cooper, Clio S. I. Der Sarkissian and Wolfgang Haak are members of The Genographic ConsortiumWe have analyzed human genetic diversity in 33 Old World populations including 23 populations obtained through Genographic Project studies. A set of 1,536 SNPs in five X chromosome regions were genotyped in 1,288 individuals (mostly males). We use a novel analysis employing subARG network construction with recombining chromosomal segments. Here, a subARG is constructed independently for each of five gene-free regions across the X chromosome, and the results are aggregated across them. For PCA, MDS and ancestry inference with STRUCTURE, the subARG is processed to obtain feature vectors of samples and pairwise distances between samples. The observed population structure, estimated from the five short X chromosomal segments, supports genome-wide frequency-based analyses: African populations show higher genetic diversity, and the general trend of shared variation is seen across the globe from Africa through Middle East, Europe, Central Asia, Southeast Asia, and East Asia in broad patterns. The recombinational analysis was also compared with established methods based on SNPs and haplotypes. For haplotypes, we also employed a fixed-length approach based on information-content optimization. Our recombinational analysis suggested a southern migration route out of Africa, and it also supports a single, rapid human expansion from Africa to East Asia through South Asia.Asif Javed, Marta Melé, Marc Pybus, Pierre Zalloua, Marc Haber, David Comas, Mihai G. Netea, Oleg Balanovsky, Elena Balanovska, Li Jin, Yajun Yang, GaneshPrasad ArunKumar, Ramasamy Pitchappan, Jaume Bertranpetit, Francesc Calafell, Laxmi Parida, The Genographic Consortiu
Impact of reactor environment on quenching heat transfer of accident tolerant fuel cladding
No full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: S.M., Massachusetts Institute of Technology, Department of Nuclear Science and Engineering, 2018Cataloged from student-submitted PDF version of thesis. Page 123 blank.Includes bibliographical references (pages 106-116).Development of accident tolerant fuels (ATF) for light water reactors (LWRs) came into focus for the nuclear engineering community after the accidents at Fukushima-Daiichi. The primary focus of the ATF program is to identify alternative fuel and cladding technologies that may provide enhanced safety, competitiveness, and economics. The new fuel design must also be compatible with present-day LWR design. For near-term applications, coatings on the nominal Zirconium-based cladding material and other metallic materials are being considered to improve the corrosion resistance and reduce the generation of hydrogen at high temperatures. Major ATF coating choices under consideration include chromium as a coating, iron-chromium-aluminum alloys (FeCrAl) as cladding and molybdenum as a coating, which have demonstrated better mechanical and oxidation behavior during the experimental testing.Thermal-fluids characteristics are pivotal for a robust testing of ATF concepts as the proposed candidates may have an entirely different thermal-hydraulic behavior when compared to Zircaloy-4. ATF coatings may display very different boiling characteristics as a result of different microstructures and surface characteristics. In the present work, transient boiling heat transfer during quenching of the candidate ATF claddings on vertical rodlets is studied experimentally. The candidate ATF material (chromium, FeCrAl, and molybdenum) are applied on Zircaloy-4 rodlets. The vertical solid rodlets are heated to temperatures up to 1000 °C and are quenched in a saturated pool of water at atmospheric pressure. The temperature variation during the quenching of rodlets was recorded insitu with synchronized visualization of boiling regimes over the test specimen using a high-speed video camera.The quench performance of the ATF coatings was analyzed based on the examination of various surface parameters such as wettability, roughness, emissivity and capillary wicking. In order to obtain a more realistic picture of the candidate performance during the emergency cooling reflood phase in a nuclear reactor, the coated rodlets are also oxidized in an autoclave before quenching. The performance of the candidate claddings is evaluated after oxidation and the surface characterized. It was observed from the post-test analysis that the surface characteristics and oxidation had a significant impact on the quench performance of ATF coatings, which varied between different coating materials. In order to better understand the thermal margins in a reactor specific environment, an analysis was performed on samples after exposing them to gamma rays. The gamma rays tend to change the surface wettability through a phenomenon called Radiation Induced Surface Activation.A Gammacell 220E irradiator that uses 12 cobalt-60 pencil sources, arranged axially in a sample chamber at MIT, was used to irradiated the samples. The results of water quenching and contact angle studies showed a higher Leidenfrost temperature and wettability in both samples exposed to gamma irradiation. The detailed microscopic analysis attributed the enhanced wettability to oxidation of the surface under gamma irradiation.by Arunkumar Seshadri.S.M.S.M. Massachusetts Institute of Technology, Department of Nuclear Science and Engineerin
Stability of n-Dimensional Additive Functional Equation in Generalized 2-Normed Space
No full textIn this paper, the author established the general solution and generalized Ulam-Hyers-Rassias stability of n-dimensional additive functional equatio
Investigations on optical properties of Eu3+ ion doped magnesium telluroborate glasses for red laser applications
No full textScreening of Pediocin Pa-1 Producing Lactic Acid Bacteria by Pcr
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Generalized Ulam- Hyers Stability of Derivations of a AQ- Functional Equation
No full textIn this paper, the author established the generalized Ulam- Hyers stability of Deriva-tions of additive and quadratic (AQ)- functional equation f(x+ y) + f(x − y) = 2f(x) + f(y) + f(−y). RESUMEN En este art́ıculo el autor establece la estabilidad generalizada Ulam-Hyers de deriva-ciones de la ecuación (AQ)-funcional cuadrática y aditiva f(x+ y) + f(x − y) = 2f(x) + f(y) + f(−y)
Luminescence properties of Er3+ ions doped bismuth borate glasses for 1.53 µm broadband optical amplifiers
No full textStructural and optical studies on Sm3+ ions doped bismuth fluoroborate glasses for visible laser applications
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