899 research outputs found

    Chapitre III. Le simandre gandi

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    Phot. 6. - Le dbu-mdzad Pad-dkar rgya-mtsho appelle à la confession des péchés.Jeu du simandre gandi. Darjeeling, monastère bka’-brgyud-pa (1979). Le terme gandi, emprunté au sanskrit, a été transcrit en tibétain avec des orthographes variables, qui tentaient de rendre compte de la prononciation d’un mot emprunté à une autre langue. Les dictionnaires relatifs au sanskrit bouddhique et en particulier celui d’Edgerton font de gandi un terme féminin que, faute de connaître l’objet désigné, ils t..

    Photograph - Gandi, Leela

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/283626Gandi, Leela306631 Item: [2003.0003.00603] "Photograph - Gandi, Leela

    Photograph - Gandi, Leela

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/283625Gandi, Leela306630 Item: [2003.0003.00602] "Photograph - Gandi, Leela

    Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology

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    Gandi capsule, a traditional Chinese herbal medicinal formulation that consists of eight herbs, is used as a clinical therapy for diabetic nephropathy. To clarify the potential synergistic mechanism, this study adopted a network pharmacology strategy to screen the action targets that corresponded to the active components in the Gandi capsule. We first constructed a compound database of 315 components in the Gandi capsule and a target database of diabetic nephropathy, which included 155 target proteins. Six representative compounds were selected to dock with 99 proteins found in the UniProtKB database with their PDB code, and interaction networks between the active ingredients of the Gandi capsule and their targets were mapped out. Results revealed 47 proteins with a high affinity with at least one compound molecule in the Gandi capsule. The main action pathways closely related to the development of diabetic nephropathy were the TGF-β1, AMPK, insulin, TNF-α, and lipid metabolism pathways as per network pharmacology analysis. In the interaction network, ACC1, SOD2, COX2, PKC-B, IR, and ROCK1 proteins had the most frequent interactions with the six compounds. We performed visual molecular docking in silico and experimentally confirmed competitive component-protein binding by SPR and an enzyme activity test, which highlighted the relationships of wogonin to COX2 and SOD2, astragaloside IV to ACC1, and morroniside to ACC1. We concluded that the potential synergistic mechanism of the Gandi capsule resulted from high affinities with multiple proteins and intervention in multiple pathways in combination therapy of diabetic nephropathy.</jats:p

    SİNEMA PERDESİNDE KIRILAN KARİZMA IŞIĞI: MAHATMA GANDİ

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    Medeniyet tarihi isimleri yüzyıllarca unutulmayan pek çok ulusal direnişliderine tanıklık etmiştir. Mahatma Gandi adıdünyada neredeyse hemen herkesçe bilinen, emperyalizme ve sömürgeciliğe direnişdendiğinde akla ilk gelen direnişliderlerinden biridir. Gandi’nin emperyalizme karşızaferle sonuçlanan eşsiz direnişini anlatan pek çok yazılıkültür ürünü bulunmaktadır. Görsel kültürün başat aktörü sayılan film sektöründe de 1992 yapımıGandi filmi, bu eşine az rastlanır direnişkarizmasınıbeyazperdeye beklenin aksine başarılıbir şekilde taşıyabilmiştir. Film lideri daha önceden tanımayan kitlelere tanıştırırken, tanıyanların da hayal dünyasına canlıbir misal olarak Gandi’yi ve ulusunun direnişhareketini yeniden sunmaktadır. Bu sunumdaki başarıda Ben Kingsley’in sıradışıoyunculuk performasının yanında filmin yapımında gerçekleştirilen üst düzey görselliğin rolü öne çıkmaktadır. Aday gösterildiği onbir oscarın dokuzunu kazanan film, film tekniğinin ve sinemalaştırma olgusunun tüm inceliklerini kullanarak Gandi karizmasınıaslıyla veya daha fazlasıyla görsel kültürde ifade etmiştir

    Comparative pharmacokinetics of four active components on normal and diabetic rats after oral administration of Gandi capsules

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    The Gandi capsule, a famous traditional Chinese medicine (TCM), is a hospital preparation that has been widely used in China for decades for the treatment of diabetes.</p

    Rosa, rosae, rosae

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    Il contributo critico offre una contestualizzazione della produzione figurativa dello scultore Fabrizio Gandi, dedicata al tema mariano

    Managing urological disorders in multiple sclerosis patients: A review of available and emerging therapies

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    Multiple sclerosis (MS) is a progressive neurological autoimmune disease with a diverse range of urological symptomatology, and most MS patients experience 1 or more moderate to severe urinary symptoms, as well as bladder and/or sexual disorders. Urologists play the director's role in evaluating and treating these patients. Therefore, identifying the proper evaluation tools and the most suitable therapeutic options for specific patients requires a thorough understanding of this disease process

    Correction: Comparative pharmacokinetics of four active components on normal and diabetic rats after oral administration of Gandi capsules

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    Correction for ‘Comparative pharmacokinetics of four active components on normal and diabetic rats after oral administration of Gandi capsules’ by Renjie Xu et al., RSC Adv., 2018, 8, 6620–6628.</p
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