196,077 research outputs found
Polymorphism of ITS1 and ITS2 regions within and between three distant population of Schizophyllum commune
No full textSchizophyllum commune is one of the most widely distributed fungi and can be isolated from all continents, except for Antarctica. It has an important role as wood decomposer since it is mostly found on fallen branches and timber of deciduous
trees, but it can also colonize softwood as well as grass silage. As an edible and medicinal mushroom, it has been shown to have various biological functions including anti-tumor, antioxidative and anti-inflammatory activity. Investigation of molecular diversity of this cosmopolitan species is important since it can make us understand what genetic traits are important in maintaining the global success of this species. In this study we analyzed polymorphisms of ITS1 and ITS2 sequences of S.
commune populations from Italy, India and China. Italian sequences were obtained from herbaria samples of S. commune
sporocarps from University of Palermo while Indian and Chinese sequences were downloaded from UNITE database. ITS1 and ITS2 regions of all analyzed sequences were extracted using ITSx software and variability of these regions was observed separately. Phylogenetic trees were constructed with MEGA 6 software using Neighbour joining method with 1000 Bootstrap replicates. Trees were constructed using ITS1 and ITS2 sequences separately, as well as concatenated ITS1 and ITS2 regions. ITS1 sequences were more variable (21,16%) than sequences of ITS2 region (11,15%). Variability of ITS1 region within Indian, Chinese and Italian population was 15,32; 5,1 and 1,45% respectively, while variation for same populations of ITS2 region was 4,29; 3,43 and 4,72% respectively. All three phylogenetic trees had
similar topologies and the best supported tree was one constructed with concatenated ITS1 and ITS2 sequences. Trees based on ITS1 and ITS2 sequences had 4 major clades within S. commune clade, while ITS1/ITS2 tree showed grouping of 6 major clades and several subclades. Majority of sequences from India were grouped in one or two distinct clades in all analyzed trees which are in correlation with their high variability within ITS1 region. Sequences from Italy and China were mostly clustered in one clade, but with low bootstrap value which indicate high similarity between them. Since there was no clear geographic clustering of the sequences from different geographic origins, our results indicate that ITS1 and ITS2 regions of the S. commune genome are not informative enough, and should be used with additional molecular markers for investigation of geographic distribution of this species. Since S. commune is one of the most widely distributed fungi it can be possible that our results indicate that populations of S. commune have global homogeneity achieved by intensive gene flow through long distance spore dispersal
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management
No full textConvulsions; Farmacodinàmica; ElectroencefalogramaConvulsiones; Farmacodinámica; ElectroencefalogramaSeizures; Pharmacodynamics; Electroencephalogram[Galovic M] Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland. Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, UK. Chalfont Centre for Epilepsy, Chalfont St Peter, UK. [Ferreira-Atuesta C] Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, UK. Chalfont Centre for Epilepsy, Chalfont St Peter, UK. Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, USA. [Abraira L] Unitat d’Epilèpsia, Servei de Neurologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Döhler N] Specialist Clinic for Neurorehabilitation, Kliniken Beelitz, Beelitz-Heilstätten, Germany. [Sinka L] Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland. [Brigo F] Division of Neurology, “Franz Tappeiner” Hospital, Merano, ItalyOpen Access funding provided by Universität Zürich. No sources of funding were used to conduct this study or prepare this manuscript
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
Rapid Selective Detection of Ascorbic Acid Using Graphene-Based Microfluidic Platform
No full textIn this paper, we present a compact microfluidic platform for selective detection of ascorbic acid. The microfluidic chip was fabricated by xurography technique with microfluidic channel placed between the silver electrodes. To increase the conductivity of the platform and enhance electron transfer process, a graphene sheet was deposited in the gap between the electrodes. The suspension of tablets with ascorbic acid and a mixture of ascorbic acid and isomalt, a sugar substitute, were injected in the microfluidic channel. Measuring electrical parameters at the silver contacts, it was possible to successfully differentiate ascorbic acid from isomalt. The sensing mechanism of the developed microfluidic platform is based on the increase of the overall conductivity with the increase of the concentration of ascorbic acid, resulting in the decrease of the resistive parameters and increase of the capacitive parameters of the proposed equivalent electrical circuit. The addition of graphene was found to improve the response linearity by 5.28% and lower the limit of detection and quantification by 12%, compared to the reference structure without graphene
How are BOLD Measures and Connectivity Affected by Noise Removal in Resting-state and Task fMRI
No full textFunctional magnetic resonance imaging (fMRI), based on blood-oxygenated-level dependent (BOLD) contrast, is a powerful non-invasive tool to assess brain function and connectivity in vivo. However, as BOLD signals are noisy, properly recovering the signal of interest from noise-related uctuations is essential to obtain reliable measures. To this end, several pre-processing pipelines have been developed, mainly adopting nuisance regression and independent component analysis (ICA). While previous works assessed the impact of these cleaning methods on resting-state fMRI (rs-fMRI) time-series and focused on specic aspects of signal cleaning (e.g. motion removal), their wider effect on both resting-state and task fMRI is yet to be fully investigated. In this work, we aimed to assess the inuence of different pre-processing methods on BOLD measures, by considering a rs-fMRI dataset, where no a priori information regarding which brain areas are expected to be active is present, and a task fMRI dataset, for which there is a strong hypothesis regarding active brain areas
Noise removal in resting-state and task fMRI: functional connectivity and activation maps
No full textOBJECTIVE: BOLD-based fMRI is a widely used non-invasive tool for mapping brain function and connectivity. However, the BOLD signal is highly affected by non-neuronal contributions arising from head motion, physiological noise and scanner artefacts. Therefore, it is necessary to recover the signal of interest from the other noise-related fluctuations to obtain reliable functional connectivity results. Several pre-processing pipelines have been developed, mainly based on nuisance regression and ICA. The aim of this work was to investigate the impact of seven widely used denoising methods on both resting-state and task fMRI. APPROACH: Task-fMRI can provide some ground truth given that the task administered has well established brain activations. The resulting cleaned data were compared using a wide range of measures: motion evaluation and data quality, resting-state networks and task activations, functional connectivity. RESULTS: Improved signal quality and reduced motion artefacts were obtained with all advanced pipelines, compared to the minimally pre-processed data. Larger variability was observed in the case of brain activation and functional connectivity estimates, with ICA-based pipelines generally achieving more reliable and accurate results. SIGNIFICANCE: This work provides an evidence-based reference for investigators to choose the most appropriate method for their study and data
Simulation of thermal plant optimization and hydraulic aspects of thermal distribution loops for large campuses
No full textFollowing an introduction, the author describes Texas A&M University and its utilities system. After that, the author presents how to construct simulation models for chilled water and heating hot water distribution systems. The simulation model was used in a $2.3 million Ross Street chilled water pipe replacement project at Texas A&M University. A second project conducted at the University of Texas at San Antonio was used as an example to demonstrate how to identify and design an optimal distribution system by using a simulation model. The author found that the minor losses of these closed loop thermal distribution systems are significantly higher than potable water distribution systems. In the second part of the report, the author presents the latest development of software called the Plant Optimization Program, which can simulate cogeneration plant operation, estimate its operation cost and provide optimized operation suggestions. The author also developed detailed simulation models for a gas turbine and heat recovery steam generator and identified significant potential savings. Finally, the author also used a steam turbine as an example to present a multi-regression method on constructing simulation models by using basic statistics and optimization algorithms. This report presents a survey of the author??s working experience at the Energy Systems Laboratory (ESL) at Texas A&M University during the period of January 2002 through March 2004. The purpose of the above work was to allow the author to become familiar with the practice of engineering. The result is that the author knows how to complete a project from start to finish and understands how both technical and nontechnical aspects of a project need to be considered in order to ensure a quality deliverable and bring a project to successful completion. This report concludes that the objectives of the internship were successfully accomplished and that the requirements for the degree of Degree of Engineering have been satisfied
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