121,865 research outputs found

    Unruptured Giant Aneurysm of Sinus of Valsalva

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    An apparently healthy young adult was referred for echocardiography because of a cardiac 2/6 diastolic murmur, heard during physical examination in the context of our competitive sports screening progra

    Can migration from West Africa be prevented by climate-resilient agriculture? Lessons in im/mobility from rural Gambia

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    How should policymakers respond to the reality and future prospect of vast populations being displaced and relocated in an era of global heating? With climate change looming, anxiety over immigration from the Global South is increasingly fuelled by apocalyptic fears of ecological breakdown. "Climate Justice and Migration. Mobility, Development, and Displacement in the Global South" offers fresh perspectives on the relationship between climate change and human migration, questioning the pessimistic prisms of ‘security’ and market-oriented approaches to ‘adaptation’ that currently guide policy. In a world increasingly shaped by climate instability and inequality, the contributors make an impassioned call for the incorporation of justice within frameworks of environmental and migration governance.How should policymakers respond to the reality and future prospect of vast populations being displaced and relocated in an era of global heating? With climate change looming, anxiety over immigration from the Global South is increasingly fuelled by apocalyptic fears of ecological breakdown. "Climate Justice and Migration. Mobility, Development, and Displacement in the Global South" offers fresh perspectives on the relationship between climate change and human migration, questioning the pessimistic prisms of ‘security’ and market-oriented approaches to ‘adaptation’ that currently guide policy. In a world increasingly shaped by climate instability and inequality, the contributors make an impassioned call for the incorporation of justice within frameworks of environmental and migration governance

    Pulse-Cancellation Echocardiography for Clinical Evaluation of Myocardial Scar Burden

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    Purpose of Review: Echocardiography has been completely abandoned as far as myocardial tissue characterization is concerned, but recently, the possibility to detect scarred myocardial tissue has been revived. We review the most recent studies aiming to assess the presence of myocardial fibrosis or scar using echocardiography. Recent Findings: The use of a simple and clinically available ultrasound, such as method pulse-cancellation, is a promising add-on to standard echocardiography for the detection of scarred myocardial tissue, mostly, but not only, in the setting of post-myocardial infarction patients. Summary: Pulse-cancellation technique, available since at least 20 years ago on commercial ultrasound machines, is reasonably accurate to detect myocardial scar tissue caused by recent or prior myocardial infarction, the accuracy varying depending on the spatial distribution of myocardial scars in the left ventricle. Severe myocardial fibers disarray, as found in hypertrophic cardiomyopathy, can also be detected by this ultrasound method

    Contrast Stress Echocardiography Findings in Myocardial Bridging Compared to Normal Coronary Course, With and Without Coronary Artery Disease

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    Background: Myocardial bridging (MB) correlation with ischemia remains a diagnostic challenge. There is a lack of studies that have assessed MB using contrast stress echo and compared the findings with those in patients demonstrating a normal coronary course, with or without obstructive coronary artery disease (CAD). Methods: We evaluated all consecutive patients who underwent contrast stress echocardiography and coronary computed tomography angiography (CCTA) due to suspected symptoms of CAD within 3 months in Parma Hospital. Coronary computed tomography angiography served as the reference standard for detecting MB and obstructive CAD. The patients were divided into 3 groups: (1) MB and no evidence of obstructive CAD (MB group, N = 64), (2) no evidence of obstructive CAD or MB (NoCAD group, N = 135), (3) obstructive CAD without MB (CAD group, N = 68). Results: The coronary flow velocity reserve in the LAD (CFVR-LAD) was reduced in the MB and CAD groups, measuring 1.91 ± 0.21 and 1.82 ± 0.28, respectively, whereas it was 2.27 ± 0.34 in the NoCAD group (P < .001). The MB and CAD groups exhibited a higher prevalence of reversible myocardial perfusion defects (rMPDs) compared to the NoCAD group (57.8% vs 64.7% vs 3.7%, P < .001). Reversible wall motion abnormalities were frequently observed in the CAD group and rarely found in the MB and NoCAD groups (47.1% vs 18.8% vs 4.4%, P < .001). In multivariable analyses, the presence of MB was independently associated with reduced CFVR-LAD (odds ratio = 14.55; 95% CI, 6.84-30.93; P < .001) and the presence of rMPD (odds ratio = 37.96; 95% CI, 13.49-106.84; P < .001). Patients with deep MB (>2 mm depth) and very deep MB (≥5 mm depth) exhibited significantly greater CFVR-LAD reduction and rMPD than those with superficial MB. Conclusions: Myocardial bridging is capable of inducing rMPD and reducing CFVR-LAD similar to obstructive CAD. The depth of the MB correlates with the abnormalities found in the stress echo evaluation. Contrast stress echo may serve as a valuable noninvasive tool for evaluating patients with MB

    A heart-shaped heart

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    We report the case of an obese 61-old man without cardiac disease history presented with exertional dyspnea. Transthoracic echocardiography could barely visualize the heart because of severely insufficient acoustic windows. After an intravenous bolus of ultrasonographic contrast media, contrast echocardiography revealed a surprising left ventricle a “heart shape,” the way the heart is represented in children’s iconography. Cardiac magnetic resonance showed a thrombus at the bottom of the aneurysm, which was not detectable by echocardiography. The advantage of cardiac magnetic resonance imaging is its capability to obtain high-quality images using infinite spatial planes, independently of acoustic windows, which limit echocardiographic views to a few standard planes
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