1,721,002 research outputs found
Unexpected death due to a biventricular thrombosis: Case report and review of literature
Cardiac thrombosis is an unusual condition characterised by the formation of a clot in the heart chambers. Biventricular thrombosis with obstruction of blood flow and fatal cardiogenic shock is anecdotal. This report describes a rare biventricular thrombosis in an elderly woman without known risk factors which was diagnosed at autopsy. A complete autopsy is essential to ascertain the cause of death, especially in complex cases with little medical history. We suggest a possible explanation for the pathophysiological mechanism
Mixed Hepatoblastoma With Small Cell Undifferentiated Pattern Predominance: A Rare Morphologic and Immunocheckpoint Profile
Malignant brain tumour with challenging intraoperative findings
This case report describes a rare and challenging glioblastoma variant with a biphasic morphology comprising both giant cell and primitive neuronal components. The tumour exhibited aggressive features and was difficult to diagnose during the intraoperative evaluation due to the predominance of small blue cell morphology, which complicated differentiation from haematological and metastatic lesions. Immunohistochemistry and molecular profiling confirmed a glioblastoma, IDH-wildtype, with combined giant cell and primitive neuronal features, and the p53 mutation in both components is a novel finding with potential implications for diagnosis and treatment. This report emphasises the importance of recognising morphological diversity in glioblastoma to avoid misdiagnosis and enable appropriate clinical management
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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