1,720,955 research outputs found
Effects of Unbalanced Polyunsaturated Fatty Acid Intake on Obesity-related Metabolic and Hepatic Dysfunctions
No full textIn obesity, BARD (BMI, AST/ALT Ratio, presence of Diabetes) score, positive for values ≥2, is a non-invasive marker of liver fibrosis. Unbalanced dietary habits are related to metabolic and liver dysfunctions. The aims were to investigate in Italian obese patients the prevalence of insulin resistance (IR) and positive BARD; the evaluation of excessive, or deficient, nutrient intakes and their relationship with IR and/or liver fibrosis. From the 220 records, 198 obese patients were included. Anthropometric measurements, HOMA-IR, BARD score and the nutrient intakes, as variances over or below the Recommended Dietary Allowances (RDAs) by the dietary assessment, were calculated as 50th (25th, 75th) percentile. HOMA-IR was in 68% averaging 3.53 (2.26, 5.66), and positive BARD in 42%. Excessive ω-6 fatty acid intake was associated with high and significant risk (OR 5.01) of IR, as well as of liver fibrosis (OR 5.67). Excessive ω-6 fatty acid intake enhances ω-6-derived eicosanoids, inducing liver inflammation and fibrosis
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
THE ROLE OF POLYUNSATURATED FATTY ACIDS IN THE LIVER DISEASE PROGRESSION IN OBESE PATIENTS
No full textBackground and aim: In obesity NAFLD is associated with insulin resistance (IR), that may induce advanced liver fibrosis leading to cirrhosis, through NASH. BARD score (BMI, AST/ALT Ratio, Diabetes mellitus) is reported to predict accurately advanced liver fibrosis (score >= 2 points). Liver damage could be also affected by inadequate nutrient intakes in obese subjects. The aim was to investigate in obese patients the relationships between nutrient intakes and the markers of metabolic and liver dysfunction.
Material and methods: From June 2010 to September 2014, 198 obese (BMI 40.4±6.5 kg/m2) inpatients (F 150, aged 42.5±11.4 yr) were admitted to the study, under their informed consent. HOMA-IR (values>2.5) and BARD score
(>=2 points) were calculated. Patients with T1DM, HBV (+), HCV (+), alcohol abuse, and steatogenic drugs in the history, were excluded. Dietary habits were obtained by detailed questioning and the recommended dietary allowances
(RDAs) for the Italian population were used as the reference range. To highlight the variation of each selected nutrient from the corresponding RDA, we calculated the rate of variance, as a percent value, over or below the RDA. Results: The following prevalences were observed, T2DM (11.1%), HOMAIR >2.5 (67.2%), AST/ALT ratio >0.8 (53.5%), BARD score >=2 points(42.4%). The rate of variances for each nutrient, as percent values, overor below the RDA, are reported in the table, expressed as 50th, 25th, 75th percentile. The logistic regression shows that BARD score >=2 points is significantly associated with the very low intake of PUFA which is, as median, 42% below the RDA (OR 5.3; 95% CI: 1.8–37.5). The inadequately low intake of PUFA is significantly associated with the HOMA-IR (OR 9.8; 95% CI:1.7–57.2). On the other hand the excessive -6 fatty acid intake, 60% over the RDA in the median value, is significantly associated with a positive BARD
score (OR 8.2; 95% CI: 1.8–37,5).
Conclusions: We observed that the highest variation rates were for fat and protein, and especially for animal protein, averaging 273% over the RDA, without significant association with the investigated markers. The low PUFA
intake is associated with increased risk of IR and liver dysfunction. The excessive -6 fatty acid intake, highly associated with positive BARD score, suggests a close relation with liver inflammation and fibrosis, probably due to the increased levels of 6-derived pro-inflammatory eicosanoids
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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