1,721,146 research outputs found

    Territorial longitudinal strain discloses the culprit vessel in a patient with non-ST-segment elevation acute coronary syndrome

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    For the study relating to this case report see A. I. Guaricci, G. Chiarello, E. Gherbesi, L. Fusini, N. Soldato, P. Siena, et al. Coronary-specific quantification of myocardial deformation by strain echocardiography may disclose the culprit vessel in patients with non–ST-segment elevation acute coronary syndrome. European Heart Journal Open 2022; doi: 10.1093/ehjopen/oeac010

    Pulse-Cancellation Echocardiography for Clinical Evaluation of Myocardial Scar Burden

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    Purpose of Review: Echocardiography has been completely abandoned as far as myocardial tissue characterization is concerned, but recently, the possibility to detect scarred myocardial tissue has been revived. We review the most recent studies aiming to assess the presence of myocardial fibrosis or scar using echocardiography. Recent Findings: The use of a simple and clinically available ultrasound, such as method pulse-cancellation, is a promising add-on to standard echocardiography for the detection of scarred myocardial tissue, mostly, but not only, in the setting of post-myocardial infarction patients. Summary: Pulse-cancellation technique, available since at least 20 years ago on commercial ultrasound machines, is reasonably accurate to detect myocardial scar tissue caused by recent or prior myocardial infarction, the accuracy varying depending on the spatial distribution of myocardial scars in the left ventricle. Severe myocardial fibers disarray, as found in hypertrophic cardiomyopathy, can also be detected by this ultrasound method

    Kisspeptin in the early postpartum of the dairy cow.

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    Recently, a new molecule, kisspeptin (Kp), and in particular Kisspeptin 10 (Kp10), was implicated in stimulating the hypothalamic–pituitary–gonadal axis. The aim of this study was to evaluate circulating Kp10 levels in the early post–partum period of the dairy cow. Blood samples were collected from 40 dairy cows, at 10 (T10), 12 (T12), 14 (T14) and 16 (T16) days after calving. Progesterone (P4) levels were evaluated using ELISA, and levels of oestrogens (E2) and Kp were evaluated using a radio‐immunologic method. After an initial plateau, Kp10 significantly increased at T14 and decreased at T16. The P4 and E2 mean serum values remained in the physiological range. It is likely that Kp10 enhanced hypothalamic GnRH release as well as pituitary gonadotropin secretion, thus promoting follicular growth and the increase in E2 levels, which might have further enhanced Kp10 release through a positive feedback loop. To our best knowledge, this is the first report on the range of Kp10 blood concentration during the early post–partum period in the dairy cow. The results of our study will increase our current understanding of the complex neuro‐endocrine crosstalk underlying the resumption of ovarian cyclicity in the dairy cow

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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