4,377 research outputs found
La morte di Pasolini tra macchinazioni di Servizi segreti e di “Palazzo”. Conversazione con David Grieco
No full textConversazione con lo scrittore e regista David Grieco, autore del libro e del film La Macchinazione; uno studio serio, approfondito e comparatistico sulla figura, l’opera e la tragica fine di Pier Paolo Pasolini.Conversation with writer and director David Grieco, author of the book and movie The Machination; seriousstudy, thorough and comparative law on the fi-gure, the work and the tragicdeath of Pier Paolo Pasolini
Motivi letterari nei libri per l’infanzia di Paolo Di Paolo
No full textThe article, organised in the form of a discussion, aims to analyse the themes and motifs of Paolo Di Paolo’s works that are addressed to young audiences. The author has recently published a large number of volumes directed just at younger readers. When beholding the titles that constitute the author’s bibliography, the reader is struck by Di Paolo’s predisposition to transform literary classics: as much in Giacomo il signor bambino as in the edition of the Divina Commedia, the author’s goal is to try to reach his new readers. Therefore, Di Paolo proves to be a prolific author of the genre; in fact, in his bibliography, volumes of fairy tales with a classic slant, such as La mucca volante, are listed as well.L’articolo contiene un’analisi di temi e di motivi delle opere di Paolo Di Paolo dirette al pubblico più piccolo. L’autore negli ultimi anni ha pubblicato un cospicuo numero di volumi indirizzati, infatti, proprio ai lettori più giovani. Ciò che stupisce scorgendo i titoli che costituiscono la bibliografia dell’autore, è la predisposizione a trasformare i classici della letteratura: tanto in Giacomo il signor bambino quanto nell’edizione della Divina Commedia l’obiettivo è cercare di raggiungere i lettori più giovani. Di Paolo si dimostra, quindi, un autore prolifico del genere, tant’è che nell’elenco non mancano volumi fiabeschi dal taglio classico come La mucca volante. Analizzare le opere giovanili dello scrittore costituisce un fatto inedito
Natural and synthetic peptides in the cardiovascular diseases: An update on diagnostic and therapeutic potentials
No full textSeveral peptides play an important role in physiological and pathological conditions into the cardiovascular system. In addition to well-known vasoactive agents such as angiotensin II, endothelin, serotonin or natriuretic peptides, the vasoconstrictor Urotensin-II (Uro-II) and the vasodilators Urocortins (UCNs) and Adrenomedullin (AM) have been implicated in the control of vascular tone and blood pressure as well as in cardiovascular disease states including congestive heart failure, atherosclerosis, coronary artery disease, and pulmonary and systemic hypertension. Therefore these peptides, together with their receptors, become important therapeutic targets in cardiovascular diseases (CVDs). Circulating levels of these agents in the blood are markedly modified in patients with specific CVDs compared with those in healthy patients, becoming also potential biomarkers for these pathologies. This review will provide an overview of current knowledge about the physiological roles of Uro-II, UCN and AM in the cardiovascular system and their implications in cardiovascular diseases. It will further focus on the structural modifications carried out on original peptide sequences in the search of analogues with improved physiochemical properties as well as in the delivery methods. Finally, we have overviewed the possible application of these peptides and/or their precursors as biomarkers of CVDs
When Macrocyclic Peptides Meet the Crystal Structure of a Melanocortin Receptor
No full textThis work reveals some key factors for the design of a novel generation of selective melanocortin ligands at the MC4 receptor
Pier Paolo Pasolini e la società: il "sogno di una cosa" travolto dalla "nuova preistoria"
No full textL’articolo prende in esame – nel centenario della nascita – il “pensiero politico” di Pier Paolo Pasolini. Vengono pertanto scandagliati (soprattutto) i suoi scritti sulla società, ma frequenti sono le incursioni nella letteratura e soprattutto nel cinema di questo autore del tutto originale. Ne emerge lo spessore di concetti spesso usati dal poeta per analizzare e criticare il presente: Nuova Preistoria, nuovo capitalismo, consumismo, edonismo, il Potere, il Palazzo, il Processo, sviluppo e progresso, sacralità in primis. Si evidenzia inoltre come l’occhio e il giudizio di Pasolini siano stati principalmente guidati dalla passione e solo di rimando dalla ragione. Un ruolo non secondario nella sua percezione del reale ha inoltre assunto la sua omosessualità. Nella parte finale dello scritto si analizzano alcuni strumenti tecnici utilizzati dall’autore per svolgere la propria opera di comprensione del presente e della sua conseguente traduzione artistico-critica.The article examines - in the centenary of his birth - the "political thought" of Pier Paolo Pasolini.
Therefore, it scrutinizes (above all) his writings on society, but there are frequent incursions into the literature and especially into the cinema of this completely original author. What emerges is the depth of concepts often used by the poet to analyze and criticize the present: New Prehistory, new capitalism, consumerism, hedonism, Power, the Palace, the Process, development and progress, sacredness in primis. It also shows how Pasolini's eye and judgment were mainly guided by passion and only by reason. His homosexuality also played a significant role in his perception of reality. In the final part of the paper we analyze some technical tools used by the author to carry out his work of understanding the present and its consequent artistic-critical translation
La voce di Pasolini
No full textNachdem die Polizei den in der Nähe von Ostia aufgefundenen, brutal zugerichteten Leichnam identifiziert hatte, erfuhr Graziella Chiarcossi als erste vom Tod ihres Cousins Pier Paolo Pasolini. Die Beamten benachrichtigten die Angehörigen in der Nacht auf den 2. November 1975 telefonisch. Chiarcossi, die damals Literaturwissenschaft studierte, lebte schon einige Jahre in der Wohnung von Pier Paolo und Susanna Pasolini in Rom. Sie hat sich intensiv für das Werk von Pasolini eingesetzt, der von Matteo Cerami und Mario Sesti realisierte Film ‘La voce di Pasolini’ (2006) entstand in enger Zusammenarbeit mit ihr. Nach der Vorführung des Films, der auch bislang unbekanntes Material des späten Filmprojekts »Porno-theo-kolossal« von Pasolini zeigt, spricht Graziella Chiarcossi mit Manuele Gragnolati (Italianist in Oxford) und Agnese Grieco (Theaterregisseurin, Autorin und Übersetzerin) erstmals in Deutschland über ihre Erinnerungen an Pasolini und über die verstörende Aktualität seiner Ideen und Wahrnehmungen
A Softwarized and MEC-Enabled Protocol Architecture Supporting Consumer Mobility in Information-Centric Networks
No full textInformation-Centric Networking emerged as a powerful enabling technology for the provisioning of scalable and efficient real-time services in Future Internet, mobile architectures, and multi-hop wireless mesh networks. To serve mobile consumers, most of scientific contributions suggest to extend the information-centric communication primitives by means of a pull-based methodology, according to which the mobile consumer issues pending requests every time it reaches a new network attachment point. This approach, however, generates two important shortcomings. First, the requests delivered before the handover will generate stale paths with wrong forwarding information in their network routers. As a consequence, some new contents will be delivered also to previous locations, thus wasting bandwidth. Second, during handovers, mobile consumers may miss some contents released in real-time and lose the synchronization with the remote producer. In order to solve these issues, this work conceives a novel protocol architecture that successfully integrates and properly customizes the key functionalities of Information-Centric Networking, Multi-access Edge Computing, and Software Defined Networking paradigms. Specifically, the designed approach envisages that (1) Multi-access Edge Computing assists mobile consumers in retrieving data, while transparently managing the information-centric communication primitives and recovering the synchronization with the remote producer after the handover, (2) Software-Defined Controllers dynamically configure forwarding functionalities, and (3) Information-Centric Networking enables efficient data dissemination and delivers network control instructions. The impact of the devised protocol architecture on the communication overhead is analytically formulated and evaluated in scenarios with different topology, mobility, application settings, and number of mobile consumers. The comparison with respect to the pure Information-Centric Networking deployment demonstrates that the proposed solution ensures a reduction of the communication overhead up to 99.99% on the data plane, an overall bandwidth saving up to 99.93%, and a not negligible memory saving in intermediary routers. At the same time, the adoption of information-centric communication primitives for the control plane achieves an overhead reduction ranging from 29.36% to 51.13% with respect to an implementation based on the conventional OpenFlow protocol
La certificazione energetica degli edifici ed il D.Lgs. 192 del 9/8/2005 – Algoritmi di calcolo ed esperienze internazionali. Edifici ad alta efficienza
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