1,720,991 research outputs found
Evaluation of plasma oxidative stress, with or without antioxidant supplementation, in superficial partial thickness burn patients: a pilot study
No full textBackground: Oxidative stress is one of the main causes of pathophysiological alterations observed during burn injury. The present pilot study aimed to determine whether a specific oral antioxidant supplementation could in any way influence free radical blood values in patients affected by superficial partial thickness burns. Materials and methods: Plasma oxidants and plasma antioxidant capacity were analysed in 20 superficial partial thickness burn patients for a 2-week period; patients were randomly divided into two groups, one of which was supported with a specifically designed oral antioxidant formula (Squalene 100 mg, Vitamin C 30 mg, Coenzyme Q10 10 mg, Zinc 5 mg, Beta Carotene 3.6 mg, Bioflavonoids 30 mg, Selenium 55 mcg) administered daily, starting from the day of admission, for the whole study period. Results: No significant differences were found in plasma oxidants and plasma antioxidant capacity between the two groups of patients. Conclusions: These results did not reflect any significant benefits of an antioxidant oral supplementation at usual dosages when considering oxidative plasmatic values of superficial partial thickness burn patients
Autologous fat transplantation for secondary breast reconstruction: Our experience
No full textBackground. Autologous fat transplantation is used after breast reconstruction to improve the breast profile. There are a variety of different methods used for fat harvesting, preparation, and reinjection. This study describes the specific techniques we used in this series of autologous fat transplantations in breast reconstruction patients and reports their outcomes compared with other studies in the literature. Patients and methods. At the University Hospital of Parma between May 2012 and December 2016, we performed 53 autologous fat transplantations for secondary breast reconstruction patients with an average age of 49 years (range: 34â65 y). A tumescent fluid (NaCl, epinephrine, and a local anaesthetic) was injected, and the lipoaspirate was harvested using a closed aspirationâinjection system connected to a 50 ml syringe, a 4 mm infiltration cannula, and a -650 mmHg vacuum. The average amount of lipoaspirate obtained was 100 ml (range: 50â200 ml). Centrifugation of the lipoaspirate (3000 rpm for 3 min) was performed to isolate the adipose tissue (average amount obtained, 80 ml; range: 30â180 ml). Under local anaesthesia, the retrograde injection of thin layers of fat graft in multiple tunnels was performed in the subcutaneous and/or subglandular planes. Results. Average follow-up was six months. Comparable to other studies, our complication rate was 7.4% (n = 4/53) and included cyst formation at the injection site (n = 1/53) and hematoma at the donor site (n = 3/53). Repeat fat grafting was performed in 28.3% of patients (n = 15/53) due to fat graft resorption. Conclusions. Autologous fat transplantation is a useful procedure for correcting irregularities in the breast contour in secondary breast reconstruction
From liposuction to adipose-derived stem cells: indications and technique
No full textAdipose tissue is an organ of energy storage, an endocrine organ, a soft tissue filler and a cosmetically unnecessary tissue discarded by liposuction. Liposuction was designed to correct unaesthetic deposits of subcutaneous fat; it produces satisfactory silhouette contouring when performed by appropriately trained operators using properly selected technologies. However, from lipoaspirate it is possible to obtain autologous fat graft and adipose-derived stem cells (ASCs) for reconstructive surgery and regenerative medicine. Autologous fat transplantation uses include the correction of body contour, malformations and post-surgical outcomes. The regenerative properties of ASCs allow treating damaged tissues such as wounds, burns, scars and radiodermatitis. The aim of this study was to perform a literature review highlighting the crucial role of adipose tissue in plastic and reconstructive surgery, from liposuction to lipofilling and ASCs, exposing the indications, procedures and complications of these surgical techniques
The art and science beyond body contouring a solution for massive weight loss patients
No full textThe massive weight loss often resulted in an excess of loose skin mainly in the abdomen, upper arms, thighs, chest, back, and laterally on the back. Consequently, most patients sought for a solution, provided by the plastic surgery through the body-contouring surgery. Abdominoplasty, arm lift, tight lift, breast lift, and liposuction are all body contouring procedures that aim to reshape the patients' body. Furthermore, body-contouring surgery can improve the patients' physical discomfort in daily life, also helping in the maintenance of normal BMI (body mass index) in formerly obese patients, thus having a positive aesthetic and psychosocial outcome. A key component of body contouring after massive weight loss is managing patient expectations. Understanding the risks of body contouring's procedures is important for patient counseling and the informed consent process. The goal of this study was to perform a literature review concerning the indication, surgical technique, outcomes and complications of body-contouring surgery
Transcutaneous oximetry and laser Doppler flowmetry values in patients with chronic skin ulcers treated with platelet rich plasma and stromal vascular fraction cells: a pilot study
No full textBackground Stromal vascular fraction cells (SVFs) hold great promise for use in regenerative medicine applications, as a result
of their ability to promote the healing process through in situ differentiation and the secretion of paracrine factors. The aim of this
paper was to evaluate whether and how the topical application of SVF with platelet-rich plasma (PRP) for the treatment of chronic
skin ulcers modified the cutaneous perfusion of the treated areas.
Methods Perilesional laser Doppler flowmetry (LDF) and transcutaneous oximetry (tcpO2) values were recorded for a 3-month
period in 15 patients with chronic skin ulcers of various etiologies, who had been previously treated with single co-administered
perilesional and intralesional injections of SVF+PRP.
Results No significant differences were found between pretreatment, 1 month, and 3 month posttreatment values regarding both
LDF values (basal: p = 0.10 and declivous: p = 0.0976) and declivous tcpO2 levels (p = 0.0804). The only significant difference
reported was between pretreatment and 3-month posttreatment basal tcpO2 levels (p = 0.0466).
Conclusions These results may reflect improved subcapillary circulation of the treated areas at 3 months postinjection, without a
significant improvement in capillary perfusion
Quality of life in post-bariatric surgery patients undergoing aesthetic abdomi-noplasty: Our experience
No full textBackground/aim of the study: Aesthetic post-bariatric surgery abdominoplasty aims to reshape the abdominal wall in order to improve the patient's appearance and self-image. Patients who have undergone this surgery report significant improvements in self-esteem and quality of life. Material and Methods: The authors evaluated the quality of life in 30 patients (22 women and 8 men) aged 24-79 years (mean age: 50.5 years) undergoing aesthetic post-bariatric surgery abdominoplasty between January 2012 and September 2015. Quality of life and body image were measured with two self-report questionnaires: a basic questionnaire (BQ) and the Body Image As-sessment-Obesity (BIA-O). Results: At the end of the study, 58% of patients reported complete satisfaction with the aesthetic results, while 23% of patients expressed dissatisfaction with the surgical scars. Analysis of the responses to the BIA-O, showed that patients had a better and slimmer body image perception after surgery than they had preoperatively. Conclusion:Although our study sample was small, we could demonstrate that most patients undergoing aesthetic post-bariatric surgery abdominoplasty experience improvement in body image perception and quality of life
Endoscopic forehead surgery for migraine therapy. Personal technique.
Full text linkAIM: The aim of this study is to prove the therapeutic effectiveness of nerve decompression, performed endoscopically for frontal migraine and by open surgery for occipital migraine.
MATERIALS AND METHODS: Twenty patients were enrolled and underwent surgery for endoscopic resection of the glabellar muscle group, including the corrugator supercilii, depressor supercilii, and procerus muscles, while the occipital decompression was performed in open surgery through decompression of occipital nerves from occipital, semispinalis capitis, trapezius and sternocleidomastoid muscles. Every patient was diagnosed with: migraine without aura, chronic tension-type headache and new daily persistent headache, refractory to medical management.
RESULTS: Analyzing the answers given by the patients to validated questionnaires, 9 referred alleviation of migraine symptoms (45%), 8 described elimination of their migraine headaches (40%) while 3 didn't report any improvement.
DISCUSSION: Our data confirmed the results of previous studies, pointing out the effectiveness of trigeminal branches and occipital nerves (trigger points) decompression from the surrounding muscles. Moreover, our technique has the same results but it's less invasive and has less collateral effects.
CONCLUSIONS: Our results highlight migraine surgery as an effective treatment for patients with migraine headaches who do not tolerate or do not wish to continue medical interventions
Surgical therapy of cutaneous squamous cell carcinoma: our experience
No full textCutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, with an excellent prognosis after surgical removal. However, nodal metastasis are present in about 5% of cases and the death rate is about 2%
Breast reconstruction with breast implants
No full textBreast cancer is the most common noncutaneous malignancy among women worldwide. After a breast cancer removal procedure, women are asked to decide about breast reconstruction, mainly to improve their life quality, and they can choose from among many options. Broadly, there are two different types of breast reconstruction procedures: prosthetic implant-based reconstruction and autologous tissue-based reconstruction
- …
