1,722,853 research outputs found

    The art of giving voice: a conversation between Laura Santini and Franziska Greber Pagine: 303-323

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    This is a conversation with artist Franziska Greber on the Art of giving voice. The academic and the art world are compared and contrasted in this conversation while discussing concept like agency, voice, being silenced, testimonial oppression and how artist work can enable people to recover the chance to speak up for themselves or to move away from marginalisation and discriminatory experiences

    Isaac Greber interview, 2017

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    Isaac Greber, an academic, lived in Moreland for a few years. He was instrumental in the creation of the Moreland Assocation. He discusses the importance of the Moreland community in his life, even after moving out of the area. He discusses the need for the Moreland Association

    Isaac Greber interview, 2017

    No full text
    Isaac Greber, an academic, lived in Moreland for a few years. He was instrumental in the creation of the Moreland Assocation. He discusses the importance of the Moreland community in his life, even after moving out of the area. He discusses the need for the Moreland Association

    In memoriam Erika Greber

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    Am 31. Juli 2011 ist Erika Greber mit nur 58 Jahren gestorben. Sie, die von 2008 bis zu ihrem Tod Beisitzerin im Vorstand der DGAVL war, ist mit Leib und Seele Komparatistin gewesen: Transkulturelles, transmediales und transhistorisches Denken war für sie selbstverständlich und sie besaß sowohl den breiten Wissenshorizont als auch den kritisch-tiefgründigen Scharfsinn, die dafür nötig sind. Mit ihr verliert die deutsche Komparatistik eine der engagiertesten, originellsten und leidenschaftlichsten Wissenschaftlerinnen. Durch plötzliche schwere Krankheit mitten aus dem Leben gerissen, konnte sie enthusiastisch anvisierte künftige Forschungsprojekte, Tagungen und Publikationen leider nicht mehr realisieren - so dass auch diesbezüglich ein Verlust zu beklagen ist, dessen Ausmaß wir nur erahnen können

    Atomically resolved images from near node photoelectron holography experiments on Al(111)

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    Szoke's concept for electron holography is hampered by forward scattering that dominates electron diffraction from electron point sources below the surface top layer. Forward scattering was proposed to be suppressed if the anisotropic nature of the electron source wave is exploited [T. Greber and J. Osterwalder, Chem. Phys. Lett. 256, 653 (1996)]. Experiments show a strong suppression of forward scattering in Al(111) if Al 2s photoelectrons (E-kin = 952 eV) are measured near the nodal plane of the outgoing p wave. The holographic reconstruction from such diffraction data provides three dimensional images of atomic sites in unit cells with a size of more than 10 Angstrom

    High-resolution cryo-EM of a small protein complex: The structure of the human CDK-activating kinase.

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    The human CDK-activating kinase (CAK) is a multifunctional protein complex and key regulator of cell growth and division. Because of its critical functions in regulating the cell cycle and transcription initiation, it is a key target for multiple cancer drug discovery programs. However, the structure of the active human CAK, insights into its regulation, and its interactions with cellular substrates and inhibitors remained elusive until recently due to the lack of high-resolution structures of the intact complex. This review covers the progress in structure determination of the human CAK by cryogenic electron microscopy (cryo-EM), from early efforts to recent near-atomic resolution maps routinely resolved at 2Å or better. These results were enabled by the latest cryo-EM technologies introduced after the initial phase of the "resolution revolution" and allowed the application of high-resolution methods to new classes of molecular targets, including small protein complexes that were intractable using earlier technology

    Atomically resolved images from near node photoelectron holography experiments on Al(111)

    No full text
    Szöke's concept for electron holography is hampered by forward scattering that dominates electron diffraction from electron point sources below the surface top layer. Forward scattering was proposed to be suppressed if the anisotropic nature of the electron source wave is exploited [T. Greber and J. Osterwalder, Chem. Phys. Lett. 256, 653 (1996)]. Experiments show a strong suppression of forward scattering in Al(111) if Al 2s photoelectrons (Ekin = 952eV) are measured near the nodal plane of the outgoing p wave. The holographic reconstruction from such diffraction data provides three dimensional images of atomic sites in unit cells with a size of more than 10 Å

    Editorial: Physical Virology and the Nature of Virus Infections

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    Virus particles, 'virions', range in size from nano-scale to micro-scale. They have many different shapes and are composed of proteins, sugars, nucleic acids, lipids, water and solutes. Virions are autonomous entities and affect all forms of life in a parasitic relationship. They infect prokaryotic and eukaryotic cells. The physical properties of virions are tuned to the way they interact with cells. When virions interact with cells, they gain huge complexity and give rise to an infected cell, also known as 'virus'. Virion-cell interactions entail the processes of entry, replication and assembly, as well as egress from the infected cell. Collectively, these steps can result in progeny virions, which is a productive infection, or in silencing of the virus, an abortive or latent infection. This book explores facets of the physical nature of virions and viruses and the impact of mechanical properties on infection processes at the cellular and subcellular levels. Keywords: Acidic pH; Active matter; Alkaline pH; Anisotropic mechanics; Cell biology; Computational virology; Genome release; Inclusion bodies; Liquid unmixing; Maturation; Mechanical properties; Modelling; Physics; Pressure; Proton diode; Reverse transcription; Stiffness; Structural evolution; Tracking; Trafficking; Uncoating; Viral lineage; Virion; Virion morphogenesis; Virus; Water wir
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