1,720,982 research outputs found
[Dent's disease: hereditary nephrolithiasis related to defective tubular endocytosis processes]
No full textA novel gene (PD1) with a potenzial role on rat spermatogenesis
No full textSettore ISI: Endocrinology and metabolism; I.F. 1.59
Transforming growth factor beta 1 induces epithelial- mesenchymal transdifferentiation (EMT) but not myofibroblast transition in human epithelial tubular cells
No full textMUTATIONAL ANALYSIS AND EXPRESSION STUDY OF THE CHLORIDE CHANNEL 5 GENE (CLCN5) IN DENT’S DISEASE AND IN IDIOPATHIC FAMILIAL NEPHROLITHIASIS
No full textTGFbeta1 induces epithelial-mesenchymal transdifferentiation (EMT) but not myofibroblast (MF) transition in human epithelial tubular cells (TEC)
No full textCaratterizzazione molecolare del gene del canale del cloro CLCN5 in pazienti con nefrolitiasi idiopatica: analisi di mutazione e studio di espressione
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
cDNA cloning and characterization of PD1: a novel human testicular protein with different expressions in various testiculopathies
No full textA novel human cDNA sequence has been isolated from human testis cDNA library. This sequence, named PD1, reveals an open reading frame encoding a protein of 520 amino acids. A partial sequence similarity has been found with the RBM gene involved in the regulation of human spermatogenesis. Northern blot analysis for PD1 mRNA from several human tissues demonstrated two distinct transcripts of 2.7 (more abundant) and 4.0 kb and revealed that PD1 is expressed in testis and to a lesser extent also in spleen, thymus, and prostate. Immunohistochemical analysis of human testis showed that this protein is detected in the cytoplasm of Sertoli cells. Antibodies against a rhPD1 fragment were used for Western blot analysis, which confirmed the presence of a 60-kDa molecule in crude extract of human testicular cells obtained from fine-needle aspiration and showed different patterns in various testiculopathies, suggesting a role for such gene in human spermatogenesis
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