131,554 research outputs found

    Decreased total venous capacity in Goldblatt hypertensive rats

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    Mean circulatory filling pressure (MCFP) and total blood volume (BV) were determined in conscious rats during the early, intermediate, and chronic phases of one-kidney, one-clip Goldblatt hypertension. MCFP was determined from arterial and venous plateau pressures during brief circulatory arrest, which was accomplished by inflating an indwelling right atrial balloon. BV as determined from plasma volume (125I-albumin), arterial hematocrit, and the F-cells factor. As compared with one-kidney sham groups, MCFP was significantly increased in one-kidney, one-clip Goldblatt hypertensive groups at 3, 14, and 28 days postclipping, whereas no significant differences in BV between hypertensive and normotensive groups were observed at any of these time periods. Total vascular compliance, estimated by measuring MCFP before and immediately after rapid BV changes, was significantly decreased in all one-kidney, one-clip Goldblatt hypertensive groups. These results indicate that venous constriction was increased and whole-body venous capacity was decreased in all three phases of one-kidney, one-clip Goldblatt hypertension studied. The mechanism leading to increased venous constriction in one-kidney, one-clip Goldblatt hypertension remains to be elucidated. </jats:p

    A review of the Schizobasis group of Drimia Jacq. (Hyacinthaceae: Urgineoideae), and the new species D. sigmoidea from Western Cape, South Africa

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    AbstractWe review the Schizobasis Baker group of Drimia Jacq. in southern Africa. We adopt a broad circumscription of D. intricata (Baker) J.C.Manning & Goldblatt as occurring widely through the summer-rainfall parts of southern and tropical Africa, and describe a second species, D. sigmoidea J.C.Manning & J.Deacon, for populations from the Worcester–Robertson Karoo in winter-rainfall Western Cape. It is distinguished from D. intricata by its distinctive, deflexed pedicels that are sharply sigmoid in fruit, and conspicuous anther connective appendage. Both species are fully described and illustrated, with a map of their distribution in southern Africa

    New species of <i>Drimia</i> (Hyacinthaceae: Urgineoideae) allied to <i>Drimia</i> <i>marginata</i> from Western and Northern Cape, South Africa

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    Plants until now identified as Drimia marginata (Thunb.) Jessop on account of their leathery, oblong to elliptical leaves with thickened, cartilaginous margins and capitate inflorescences of campanulate flowers, are shown to comprise three sets of populations separable on leaf morphology, ecology and distribution. Typical D. marginata produces 1 (2) oblong, apiculate leaves with retrorsely-scabridulous margins and occurs in fine-grained clay soils on the Hantam and Roggeveld Plateaus. Plants from Namaqualand and the Richtersveld. described here as Drimia pulchromarginata J.C.Manning & Goldblatt. occur in sandy or gravelly soils and produce 2 -4 , elliptical to suborbicular, apiculate leaves with an ornate, duplex margin: the dorsal surface bears a submarginal band of dense, velvety trichomes fringing the thickened, colliculate margin. A third series of populations from seasonally moist sandstones at higher altitude on the interior mountains of the West Coast produces2 or 3(4) narrowly oblong, obtuse leaves with a simple, papillate or colliculate margin and are recognized as D. ligulata J.C.Manning & Goldblatt. A fourth taxon with a similar capitate inflorescence of campanulate flowers produces a solitary, subterete or subclavate leaf, elliptical in section. Recorded from scattered localities in the Northern and Western Cape', it is here described as D. vermiformis J.C.Manning & Goldblatt

    Pericardial effusions in two boys with chronic granulomatous disease.

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    Pediatr Radiol. 1999 Nov;29(11):820-2. Pericardial effusions in two boys with chronic granulomatous disease. Macedo F, McHugh K, Goldblatt D. SourceDepartment of Radiology, Hospital Geral de Santo Antonio, Porto, Portugal. Abstract Pericardial involvement in chronic granulomatous disease (CGD) is very rare. We present two children with known CGD and pericardial effusions in whom no microbial cause for the effusions was found. PMID: 10552060 [PubMed - indexed for MEDLINE

    Aristea ranomafana Goldblatt, a new species of Iridaceae from Madagascar

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    Volume: 17Start Page: 159End Page: 16

    Economic Inequality and the Right to Social Security: Contested Meanings and Potential Roles

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    The right to social security, widely referred to in international human rights law, including in International Labour Organization conventions, is also found in more than half of all constitutions in the world (Jung et al. 2014). Social security is prominent in the Sustainable Development Goals (SDGs); “social protection” is explicitly stated in three targets. The term “social protection” is often used synonymously with social security and at other times used as a broader concept with social security as a core component (Goldblatt 2016, 8–9). Goal 1 to “End poverty in all its forms everywhere” includes Target 1.3: “Implement nationally appropriate social protection systems and measures for all, including floors, and by 2030 achieve substantial coverage of the poor and the vulnerable” (UNGA 2015, 15). While the target requires social protection for “all” this idea of equality of access in ending poverty does not necessarily ensure that economic inequality will be addressed as there may still be significant differences of income and wealth within the society once this target is met

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Gender Equality and Human Rights

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    The UN Women Discussion Paper Series is a new initiative led by the Research and Data section. The Series features research commissioned as background papers for publications by leading researchers from different national and regional contexts. Each paper benefits from an anonymous external peer review process before being published in this Series. This paper has been produced for the UN Women flagship report Progress of the World’s Women 2015 by Sandra Fredman FBA QC, Hon Rhodes Professor of the Laws of the British Commonwealth and the USA, Oxford University and Beth Goldblatt, Associate Professor, University of Technology, Sydney (With valuable research assistance by Meghan Campbell, D Phil candidate, Oxford University

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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