1,720,958 research outputs found
Macular thickness in insulin-dependent patients: evaluation with OCT
No full textDiabetic patients not showing clinical alterations during routine eye examinations have been studied with OCT to evaluatewhether it would be able to show subclinical retinal modifications.
Furthermore, we analyzed whether there is a seat of topographical macular predilection for the alterations and the connection between their onset and the duration of the disease
Intracranial aneurysm and diplopia due to oculomotor nerve palsy: pre- and post operative study
No full textPurpose
The aim of this study was to analyze ocular signs and symptoms in patients with oculomotor nerve palsy due to compression exerted by an intracranial aneurysm. We compare the results of two surgical treatments (microsurgical clipping against endovascular embolisation) in relation with the size of the aneurysm and the time between diagnosis and therapeutical approach
Materials and Methods
The study involved 16 patients. Each patient underwent an ophthalmological evaluation at the baseline and immediately, 6 months and 1 year after surgery, including the study of eyelid ptosis, ocular motility, pupil function, non-concomitant strabismus, diplopia and visual acuity
Results
The best recovery was seen in the patients undergoing aneurysm clipping. Palpebral ptosis was the first sign to appear and the first to regress, followed by pupil and medial rectus function. Recovery of the other muscles was slower and often incomplete
Conclusions
Ophthalmological examination is essential for the correct treatment and follow-up of patients with intracranial aneurysmsPURPOSE: The aim of this study was to analyze ocular signs and symptoms in patients with oculomotor nerve palsy due to compression exerted by an intracranial aneurysm. We compare the results of two surgical treatments (microsurgical clipping against endovascular embolisation) in relation with the size of the aneurysm and the time between diagnosis and therapeutical approach.
MATERIALS AND METHODS: The study involved 16 patients. Each patient underwent an ophthalmological evaluation at the baseline and immediately, 6 months and 1 year after surgery, including the study of eyelid ptosis, ocular motility, pupil function, non-concomitant strabismus, diplopia and visual acuity.
RESULTS: The best recovery was seen in the patients undergoing aneurysm clipping. Palpebral ptosis was the first sign to appear and the first to regress, followed by pupil and medial rectus function. Recovery of the other muscles was slower and often incomplete.
CONCLUSIONS: Ophthalmological examination is essent
Treatment modality with anti-VEGF (Bevacizumab) in diabetic maculopathy
No full textAssessment of the therapeutic efficiency of Bevacizumab in the treatment of diabetic macular edema. Prospective study with 180-day follow-up.
30 eyes of 25 patients with diabetic macular edema underwent a cycle of 3 intravitreal injections (each dose: 1.25 mg/0.05 ml of Bevacizumab – Avastin 100), with an interval of a month between each other. The anterior segment and fundus oculi of the patients were controlled the following day. 30 days after each injection and three months after the last injection, visual acuity (BCVA) and central macular thickness using OCT
were determined
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Neuroprotection in Glaucoma: Old and New Promising Treatments
Full text linkGlaucoma is a major global cause of blindness, but the molecular mechanisms responsible for the neurodegenerative damage are not clear. Undoubtedly, the high intraocular pressure (IOP) and the secondary ischemic and mechanical damage of the optic nerve have a crucial role in retinal ganglion cell (RGC) death. Several studies specifically analyzed the events that lead to nerve fiber layer thinning, showing the importance of both intra- and extracellular factors. In parallel, many neuroprotective substances have been tested for their efficacy and safety in hindering the negative effects that lead to RGC death. New formulations of these compounds, also suitable for chronic oral administration, are likely to be used in clinical practice in the future along with conventional therapies, in order to control the progression of the visual impairment due to primary open-angle glaucoma (POAG). This review illustrates some of these old and new promising agents for the adjuvant treatment of POAG, with particular emphasis on forskolin and melatonin
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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