1,721,411 research outputs found
Evidence for anisotropy in the distribution of short-lived gamma-ray bursts
No full textMeasurements of the two-point angular correlation function w(\theta) for 407 short gamma-ray bursts collected in the Current BATSE Catalogue reveal a ~2 \sigma deviation from isotropy on angular scales \theta ~ 2-4 degrees. Such an anisotropy is not observed in the distribution of long gamma-ray bursts and hints to the presence of repeated bursts for up to ~13% of the sources under exam. However, the available data cannot exclude the signal as due to the presence of large-scale structure. Under this assumption, the amplitude of the observed w(\theta) is compatible with those derived for different populations of galaxies up to redshifts ~0.5, result that suggests short gamma-ray bursts to be relatively local sources
A unifying view of Gamma-Ray Burst afterglows
Full text linkWe selected a sample of 33 gamma-ray bursts detected by Swift, with known redshift and optical extinction at the host frame. For these, we constructed the de-absorbed and K-corrected X-ray and optical rest-frame light curves. These are modelled as the sum of two components: emission from the forward shock due to the interaction of a fireball with the circumburst medium and an additional component, treated in a completely phenomenological way. The latter can be identified, among other possibilities, as a `late prompt' emission produced by a long-lived central engine with mechanisms similar to those responsible for the production of the `standard' early prompt radiation. Apart from flares or re-brightenings, that we do not model, we find a good agreement with the data, despite of their complexity and diversity. Although based, in part, on a phenomenological model with a relatively large number of free parameters, we believe that our findings are a first step towards the construction of a more physical scenario. Our approach allows us to interpret the behaviour of the optical and X-ray afterglows in a coherent way, by a relatively simple scenario. Within this context, it is possible to explain why sometimes no jet break is observed; why, even if a jet break is observed, it is often chromatic and why the steepening after the jet break time is often shallower than predicted. Finally, the decay slope of the late prompt emission after the shallow phase is found to be remarkably similar to the time profile expected by the accretion rate of fall-back material (i.e. ~ t-5/3), suggesting that this can be the reason why the central engine can be active for a long time
The beta cell function in NIDDM patients with secondary failure: a three year follow-up of combined oral hypoglycemic and insulin therapy
No full textEleven Type 2 (non-insulin-dependent) diabetic patients, islet cell autoantibodies negative, nonobese with secondary failure to oral hypoglycemic agents (OHA) [glyburide (7.5 mg/day) and phenformin (75 mg/day)] and HbA1c 10.2 +/- 0.6% were studied. Insulin receptors on circulating monocytes, glucose utilization at supraphysiological insulin concentrations, and plasma C-peptide after i.v. glucagon were evaluated before and after 2 months of combined therapy with OHA and insulin (Ultratard HM Novo). A significant improvement was demonstrated in HbA1c and glycemia after two months of treatment. Glucose MCR was increased after two months of treatment whilst basal C-peptide was decreased as well as receptor binding to monocytes. After three years of combined therapy, body weight, glycemia and HbA1c did not increase. After three years the C-peptide basal values were significantly increased with respect to values found after 2 months of therapy. These results demonstrate that insulin treatment may restore insulin sensitivity in NIDDM patients resistant to OHA treatment and that after three years there is no exhaustion of B-cell function
The spectra of short gamma-ray bursts
Full text linkWe present the results of the spectral analysis of a sample of short bright γ--ray bursts (GRB) detected by BATSE and compare them with the average and time resolved spectral properties of long bright bursts. While the spectral parameters of short GRBs confirm, as expected from previous works based on the hardness ratio, that they are harder than long events, we find that this difference is mainly due to a harder low energy spectral component present in short bursts, rather than to a (marginally) different peak energy. Intriguingly our analysis also reveals that the emission properties of short GRBs are similar to the first 2 s of long events. This might suggest that the central engine of long and short GRBs is the same, just working for a longer time for long GRBs. We find that short bursts do not obey the correlation between peak frequency and isotropic emitted energy for any assumed redshift, while they can obey the similar correlation between the peak frequency and isotropic emitted luminosity. This is consistent with (although not a proof of) the idea that short GRBs emit a γ--ray luminosity similar to long GRBs. If they indeed obey the peak frequency -- isotropic luminosity relation, we can estimate the redshift distribution of short bursts, which turns out to be consistent with that of long bursts just with a slightly smaller average redshift
GRB 990413: Insight into the thermal phase evolution
Full text linkGRB 990413 shows a very hard spectrum (with a low energy spectral component F(E) \propto E^{2.49}) which is well represented by a black body model with characteristic temperature ~70 keV. It thus belongs to the subset of GRBs which might be revealing a thermal phase. We find that the temperature/luminosity evolution is consistent with that found in the other ``thermal'' GRBs. The time resolved spectral analysis indicates the presence of a second non--thermal component contributing (for about 1 s) up to 30 per cent of the total flux. Differently from the other thermal GRBs, GRB 990413 shows significantly high level of variability and the evolution of the thermal/non--thermal spectral components is strongly correlated with the flux variations. This GRB thus offers the unique opportunity to test the standard fireball photospheric and internal shock phases and their reciprocal influence. GRB 990413 was not selected on the basis of its spectrum and thus hints to the possibility that this early behavior might be more common than currently known
Extremely hard GRB spectra prune down the forest of emission models
No full textWe consider the evidence for very hard low energy spectra during the prompt phase of Gamma-Ray Bursts (GRB). In particular we examine the spectral evolution of GRB 980306 together with the detailed analysis of some other bursts already presented in the literature (GRB 911118, GRB 910807, GRB 910927 and GRB 970111), and check for the significance of their hardness (i.e. extremely steep spectral slopes below the EFE peak) by applying different tests. These bursts, detected by the Burst And Transient Source Experiment (BATSE) in the ∼30 keV -- 2 MeV energy range, are sufficiently bright to allow time resolved spectral studies on time intervals of the order of tenths of a second. We discuss the hard spectra of these bursts and their evolution in the context of several non--thermal emission models, which all appear inadequate to account for these cases. The extremely hard spectra, which are detected in the early part of the BATSE light curve, are also compared with a black body spectral model: the resulting fits are remarkably good, except for an excess at high energies (in several cases) which could be simply accounted for by the presence of a supra--thermal component. The findings on the possible thermal character of the evolving spectrum and the implications on the GRB physical scenario are considered in the frameworks of photospheric models for a fireball which is becoming optically thin, and of Compton drag models, in which the fireball boosts "ambient" seed photons by its own bulk motion. Both models, according to simple estimates, appear to be qualitatively and quantitatively consistent with the found spectral characteristics, although their possible caveats are discussed
Is taurine beneficial in reducing risk factors for diabetes mellitus?
No full textTaurine is a semiessential amino acid, and its deficiency is involved in retinal and cardiac degenerations. In recent years, it was found that diabetes mellitus (DM) is associated with taurine, and many in vivo experimental studies showed that taurine administration is able to reduce the alterations induced by DM in the retina, lens, and peripheral nerve, although its effects on diabetic kidney are dubious. Interestingly, long-term taurine supplementation reduces the mortality rate in diabetic rats. The mechanisms by which taurine exerts beneficial effects in DM are discussed below. Recently, it has been suggested that taurine deficiency may alter the endocrine pancreas "fetal programming," increasing the risk of insulin resistance in adult life. The bulk of experimental data suggests that taurine administration could be useful in the treatment of type 1 DM and in the prevention of insulin resistance
Glucose, insulin and somatostatin infusion for the determination of insulin resistance in liver cirrhosis
No full textTwelve patients with liver cirrhosis and ten normal subjects were studied. Using a constant intravneous infusion of glucose, insulin and somatostatin over 2 1/2 hours we determined the stteady state plasma glucose level (SSPG) in order to measure insulin resistance. The results demonstrated that the cirrhotic patients were insulin resistant compared to normals and that plasma glucagon does not account for the insulin resistance in these patients
Amphiphilic Cu(II) Complexes Modeled After the Metal-Complexation Subunit of Bleomycin Antibiotics
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