1,720,972 research outputs found
Quando nascono i genitori?
No full textUn bimbo viene generato non solo fisicamente ma anche psichicamente: la nascita di un bimbo implica nell'adulto l'elaborazione di processi psichici che gli consnetono di generare e di diventare genitore. E' il concepimento di un bimbo che forma il genitore, oppure la genitorialità è una funzione menatle che si è già strutturata precedentemente e il concepimento e la nascita di un bimbo ne consentono la piena espressione? Nel presente articolo si riferiscono alcuni dati preliminari di una ricerca di Psicologia Clinica perinatale in cui si stanno indagando aspetti del processo di sviluppo ed evoluzione del progetto genetativo/genitoriale della coppia. L'obiettivo dello studio è esplorare le diverse dimensioni che articolano questi complessi costrutti attraverso numerose variabili tra le quali anche la sessualità della coppia
La dimensione sessuale nel progetto generativo e genitoriale della coppia
No full textIn una nostra più ampia recente ricerca sperimentale in corso, stiamo cercando di esplorare le diverse dimensioni che si articolano nei complessi costrutti della progettualità generativa e genitoriale della coppia, attraverso numerose variabili tra le quali la sessualità generativa. La dimensione sessuale viene esplorata attraverso alcune variabili relazionali: il proprio desiderio e quello del partner, la relazione affettiva della coppia, la presenza di armonia piuttosto che tensioni nella coppia, i cambiamenti dei comportamenti relativi alla sessualità, dei propri atteggiamenti e di quelli del partner, l’organizzazione della coppia a seguito dell’evento gravidanza. Sono state coinvolte coppie alla prima generatività e pluripare: nell’ambito del presente contesto vengono evidenziati i primi risultati della indagine su quella che è la dimensione della sessualità generativa della coppia durante la gravidanza
Diventare genitori nel terzo millennio: un’indagine esplorativa preliminare per un programma di salute mentale perinatale
Full text linkIn una società che sta cambiando, in cui si sta assistendo a nuove forme di coppia e di famiglia, ci si chiede quanto questi mutamenti possano portare a eventuali cambiamenti psichici nella modalità di generare e di allevare i propri figli nel terzo millennio, per far fronte al pericolo di un indebolimento della identità genitoriale e di disturbi nello sviluppo psichico del bimbo. Nei progetti di prevenzione in ambito perinatale viene individuata pertanto l’esigenza di conoscere come le coppie che intendono generare e diventare genitori affrontino questi processi. Ènecessario che un programma di salute mentale perinatale orientato a promuovere il benessere dei genitori e del bimbo persegua l’obiettivo di sviluppare un progetto di accompagnamento al complesso processo della genitorialità psichica, a partire dal periodo prenatale in cui è possibile già cogliere indicatori di una eventuale vulnerabilità genitoriale. In questo intento abbiamo svolto una indagine preliminare che esplora aspettative, desideri, bisogni e pregresse esperienze che possono caratterizzare la generatività in una prospettiva genitorialeIn a changing society, in which we spectators of new forms of couples and families, we are trying to understand how these social mutations can lead to psychological changes in order to generate and raising children in the third millennium. This has the aim to avoid the danger of a weakening of parental identity and psychological disorders in the child development. In perinatal prevention projects we need to know how the generating couples faces to these psychosocial processes. It is necessary that a perinatal mental health program, focused on promoting the parents and the baby welfare, is oriented to achieve the aim of developing a support project to the complex process of psychic parenting. This starts from the prenatal period in which we can already identify indicators of a parental vulnerability. This is the aim with which we have begun a preliminary study to explore expectations, desires, needs and past experiences which may characterize the generativity in a parental prospectDans une société qui évolue, qui connaît des nouvelles formes de couple et de famille, on se demande comment ces changements peuvent mener à des changements psychologiques dans le mode de génération et d’élever les enfants dans le troisième millénaire, pour faire face au danger d'un affaiblissement des identités des parents et des troubles psychologiques dans le développement de l’enfant. Dans les plans de prévention pendant la période périnatale on a identifié le besoin de savoir comment les couples qui souhaitent devenir parents affrontent ces processus. Et alors il faut qu'un programme de santé périnatale mentale axés sur la promotion du bien-être des parents et de l'enfant poursuive le but de développer un projet pour accompagner le processus complexe de la parentalité psychologique, à partir de la période prénatale dans laquelle on peut pouvez déjà saisir les indicateurs d'une éventuelle vulnérabilité parentale. Dans cette optique nous avons réalisée une enquête préliminaire sur les attentes, les désirs, les besoins et les expériences antérieures qui peuvent caractériser la générativité dans une perspective parentale
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Neoadjuvant chemotherapy in the treatment of locally advanced cervical carcinoma in pregnancy
No full textRigosertib is a more effective radiosensitizer than cisplatin in concurrent chemoradiation treatment of cervical carcinoma, in vitro and in vivo.
No full textAbstract
PURPOSE: To compare rigosertib versus cisplatin as an effective radiosensitizing agent for cervical malignancies.
METHODS AND MATERIALS: Rigosertib and cisplatin were tested in cervical cancer cell lines, HeLa and C33A. A 24-hour incubation with rigosertib and cisplatin, before irradiation (2-8 Gy), was used for clonogenic survival assays. Cell cycle analysis (propidium iodide staining) and DNA damage (γ-H2AX expression) were evaluated by fluorescence-activated cell sorter cytometry. Rigosertib was also tested in vivo in tumor growth experiments on cervical cancer xenografts.
RESULTS: Rigosertib was demonstrated to induce a G2/M block in cancer cells. Survival curve comparison revealed a dose modification factor, as index of radiosensitization effect, of 1.1-1.3 for cisplatin and 1.4-2.2 for rigosertib. With 6-Gy irradiation, an increase in DNA damage of 15%-25% was achieved in both HeLa and C33A cells with cisplatin pretreatment, and a 71-108% increase with rigosertib pretreatment. In vivo tumor growth studies demonstrated higher performance of rigosertib when compared with cisplatin, with 53% longer tumor growth delay.
CONCLUSIONS: Rigosertib was more effective than cisplatin when combined with radiation and caused minimal toxicity. These data support the need for clinical trials with rigosertib in combination therapy for patients with cervical carcinoma
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