33,134 research outputs found
A nuclear protein, synthesized in growth-arrested human hepatoblastoma cells, is a novel member of the short-chain alcohol dehydrogenase family
No full textWe have described a protein (Hep27) [Donadel, G., Garzelli, C., Frank, R. & Gabrielli, F. (1991) Eur. J. Biochem. 195, 723-729] which is synthesized and accumulated in the nucleus of human hepatoblastoma (HepG2) cells, following growth arrest induced by butyrate treatment. The synthesis of Hep27 is inhibited in cells that, released from the butyrate block, have resumed DNA synthesis. This report describes the cloning and the characterization of the cDNA coding for the Hep27 protein. The translation of the Hep27 cDNA predicts an amino acid sequence that can be aligned with those of the known short-chain alcohol dehydrogenase enzymes (SCAD) family. Both the recognition of enzymic functional domains and the similarity with the SCAD family of proteins of several amino acid blocks throughout the molecule, strongly suggest that this protein is a new member of the SCAD family. In agreement with its nuclear localization Hep27 has a region similar to the bipartite nuclear-targeting sequence. The study of Hep27 mRNA expression and protein synthesis suggests the existence of a regulation at the post-transcriptional level. The possible nuclear role of the Hep27 protein is discussed
The chromomagnetic dipole operator and the B semileptonic branching ratio
No full textWe consider the possibility of having a large branching ratio for the decay b\to s g coming from an enhanced Wilson coefficient of the chromomagnetic dipole operator. We show that values of BR(b\to s g) up to \sim 10\% or more are compatible with the constraints coming from the CLEO experimental results on BR(B\to X_s\gamma) and BR(B\to X_s\phi). Such large values can reconcile the predictions of both the semileptonic branching ratio and the charm counting with the present experimental results. We also discuss a supersymmetric model with gluino-mediated flavour violations, which can account for such large values of BR(b\to s g)
Commento agli artt. 1647-1654 c.c. in Commentario del Codice Civile Ipertestuale diretto da G. Bonilini, C. Granelli, E. Gabrielli, Torino, 2000, e successive edizioni ed aggiornamenti
No full text“Seminari Clinici di Psichiatria” (Astrazeneca) - Università di Genova, Genova, 24 novembre 2010, co-relatori Prof. F. Gabrielli, L. Ferrannini, K. Fontoulakis, G. Perugi.
No full textEvento sponsorizzat
Supersymmetric corrections to '/ at the leading order in QCD and QED
No full textWe study the corrections to \epsilon^\prime /\epsilon in the minimal supersymmetric model at the leading order in QCD and QED. Supersymmetry can increase the standard model prediction for \epsilon^\prime /\epsilon by at most 40\% for m_t=174 GeV, an enhancement which is indistinguishable from the present theoretical uncertainties. The most conspicuous effect of supersymmetry is a strong depletion of \epsilon^\prime /\epsilon. For certain choices of supersymmetric parameters, vanishing and even small negative values of \epsilon^\prime /\epsilon can be obtained for the top quark in the CDF range.We study the corrections to in the minimal supersymmetric model at the leading order in QCD and QED. Supersymmetry can increase the standard model prediction for by at most 40\% for GeV, an enhancement which is indistinguishable from the present theoretical uncertainties. The most conspicuous effect of supersymmetry is a strong depletion of . For certain choices of supersymmetric parameters, vanishing and even small negative values of can be obtained for the top quark in the CDF range.We study the corrections to in the minimal supersymmetric model at the leading order in QCD and QED. Supersymmetry can increase the standard model prediction for by at most 40\% for GeV, an enhancement which is indistinguishable from the present theoretical uncertainties. The most conspicuous effect of supersymmetry is a strong depletion of . For certain choices of supersymmetric parameters, vanishing and even small negative values of can be obtained for the top quark in the CDF range.We study the corrections to ϵ ′/ ϵ in the minimal supersymmetric model at the leading order in QCD and QED. Supersymmetry can increase the standard model prediction for ϵ ′/ ϵ by at most 40% for m t = 174 GeV, an enhancement which is indistinguishable from the present theoretical uncertainties. The most conspicuous effect of supersymmetry is a strong depletion of ϵ ′/ ϵ . For certain choices of supersymmetric parameters, vanishing and even small negative values of ϵ ′/ ϵ can be obtained for the top quark in the CDF range
“Disturbo Bipolare e Depressione Resistente” (Astrazeneca). Genova, 17 dicembre 2009, co-relatori, Prof. G. Perugi, F. Gabrielli, L. Ferrannini, G. Masi, G. Maina, V. Villari, M. Vaggi.
No full textDepressione resistente e correlati con disturbo bipolar
Liber Amicorum per Dieter Henrich: Parte generale e persone, I; Famiglia e successioni, II
No full textLa pubblicazione, in due volumi, raccoglie scritti di autori italiani offerti al prof. Dieter Henrich in occasione del suo 80° compleanno
- …
