14,123 research outputs found
In vitro and in vivo expression of interleukin-1alpha and tumor necrosis factor-alpha mRNA in pemphigus vulgaris: interleukin-1alpha and tumor necrosis factor-alpha are involved in acantholysis.
No full textCompactness in the adiabatic limit of disk vortices
No full textThis paper is the first input towards an open analogue of the quantum Kirwan map. We consider the adiabatic limit of the symplectic vortex equation over the unit disk for a Hamiltonian G-manifold with Lagrangian boundary condition, by blowing up the metric on the disk. We define an appropriate notion of stable solutions in the limit, and prove that any sequence of disk vortices with energy uniformly bounded has a subsequence converging to such a stable object. We also proved several analytical properties of vortices over the upper half plane, which are new type of bubbles appearing in our compactification
© Springer-Verlag Berlin Heidelberg 20161111Nsciescopu
The pulmonary homograft: an improved conduit for right ventricular outflow tract reconstruction
No full textRecommended from our members
DN detection during SLSF tests
No full textDuring two tests in the Sodium Loop Safety Facility (W2 and P4), two systems were operated to detect delayed neutrons from exposed fuel. One monitored directly the sodium in the in-pile loop with a transit delay from the flux region of approx.2 seconds; the other conducted a sample stream of sodium to external detectors with a transit delay which could be varied from approx.10 to approx. 40 seconds. Detectors of a wide range of sensitivity were operated in pulse and current mode; DN signals varying from <1 mm/sup 2/ recoil to many grams of molten fuel could be recorded reliably without saturation. During the W2 and P4 tests a continuous DN record was made. Massive fuel failure signals were observed during reactor transients in both tests, including events interpreted as fuel melting and exposure of large areas. The steady signal from the blockage in P4 was studied as a function of reactor power and sodium temperature
<i>Mlh3</i><sup><i>DN/DN</i></sup> males show a sterile phenotype.
No full text(A, B) Mlh3DN/DN adult male testes are significantly smaller when compared to WT littermates (Mlh3DN/DN—0.28% of total body weight ± 0.06 standard deviation (s.d.), n = 13; WT—0.77% ± 0.1, n = 15; p 7 ± 4.4 sperm/mouse; p Mlh3DN/DN are absent of spermatids and spermatozoa. Higher magnification of WT and Mlh3DN/DN testes sections are shown in E and G, respectively. Black arrows in (G) indicate metaphase I spermatocytes in the Mlh3DN/DN seminiferous tubule lumen. Sg, spermatogonia; Sc, prophase I spermatocytes; St, postmeiotic spermatids. Scale bar is 100 μm. Images were taken at 40X magnification.</p
TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy
No full textBackground/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis. Mainly reported in proximal regions of the kidney, EMT is now recognized as a key contributor to the loss of renal function throughout the nephron in diabetic nephropathy (DN). Concomitant upregulation of TGF-beta in diabetes makes this pro-fibrotic cytokine an obvious candidate in the development of these fibrotic complications. This article reviews recent findings clarifying our understanding of the role of TGF-beta and associated sub-cellular proteins in EMT. Methods: To understand the pathology of EMT and the role of TGF-beta, we reviewed the literature using PubMed for English language articles that contained key words related to EMT, TGF-beta and DN. Results: EMT and phenotypic plasticity of epithelial cells throughout the nephron involves cytoskeletal reorganization and de novo acquisition of classic mesenchymal markers. Concurrent downregulation of epithelial adhesion molecules results in a loss of function and decreased cell coupling, contributing to a loss of epithelial integrity. TGF-beta 1 is pivotal in mediating these phenotypic changes. Conclusion: TGF-beta-induced EMT is a key contributor to fibrotic scar formation as seen in DN, and novel routes for future therapeutic intervention are discussed
Rethinking the role of tumour necrosis factor-alpha in ultraviolet (UV) B-induced immunosuppression: altered immune response in UV-irradiated TNFR1R2 gene-targeted mutant mice.
No full textSimple G-modules in types Bn, Cn, and Dn
No full textLet G be a simple algebraic group of type Bn, Cn, or Dn over an algebraically closed field of positive characteristic. In this thesis we determine characters of simple G-modules contained in a family of alcoves using the techniques of geometric representation theory. In particular, we utilise a novel technique to calculate the p-canonical basis of the Hecke algebra using the classical canonical basis and Braden-MacPherson sheaves on the moment graph of the affine Grassmannian of the Langlands dual group. This work generalises a family of weights for Sp2n considered by Gilmer and Masbaum using the techniques of Topological Quantum Field Theory
Disputatio Medica De Generatione Hominis In Ovo / Quam, ... Sub Praesidio ... Dn. Johannis Jacobi Waldschmied/ Medicinae Doctoris ... exhibet Author Dominicus Beddevole, Genevensis, In Auditorio Medico d. 3. Septemb. ...
No full textDISPUTATIO MEDICA DE GENERATIONE HOMINIS IN OVO / QUAM, ... SUB PRAESIDIO ... DN. JOHANNIS JACOBI WALDSCHMIED/ MEDICINAE DOCTORIS ... EXHIBET AUTHOR DOMINICUS BEDDEVOLE, GENEVENSIS, IN AUDITORIO MEDICO D. 3. SEPTEMB. ...
Disputatio Medica De Generatione Hominis In Ovo / Quam, ... Sub Praesidio ... Dn. Johannis Jacobi Waldschmied/ Medicinae Doctoris ... exhibet Author Dominicus Beddevole, Genevensis, In Auditorio Medico d. 3. Septemb. ... (1)
Titelseite (1)
Widmung (2)
Text (3
- …
