379 research outputs found
Ornamento a graffito delle facciate. La rappresentazione dell’Architettura sull’Architettura = Graffiti ornament of the façades. The representation of Architecture on Architecture.
No full textLa completa schedatura dei paramenti ornamentali a graffito dei palazzi di Pienza è stata preceduta
dalla ricerca specifica degli elementi di valutazione e catalogazione necessari.
Il rilievo diretto e il ridisegno hanno poi condotto a una tesi di laurea magistrale già discussa e a
pubblicazioni in corso di editazione sulla terminata e completa schedatura delle facciate della città.
In questo paper si rende conto degli studi preliminari condotti.
Da letteratura e documentazione si evince quanto nella Toscana del Rinascimento le facciate affrescate
fossero meno apprezzate di quelle graffite, anche a fronte di una maggiore padronanza della
tecnica da parte degli esecutori, della durabilità nel tempo e della rapidità di realizzazione. In seguito,
spesso e inspiegabilmente considerate semplici strati di protezione, anziché vere e proprie opere
d’arte e d’architettura, queste superfici sono state spesso trascurate nella manutenzione o addirittura
ricoperte da intonaco uniforme. Pressoché ignorate dalla storiografia, la perdita di molte fra esse si è
verificata prima che un corretto processo di documentazione e salvaguardia fosse definito, con la sola
sensibilità dei proprietari degli immobili a portare con sé responsabilità e onere di tutela.
L’auspicio ultimo della schedatura dei palazzi pientini, nel tentativo di ricondurre il tema della facciata
a graffito alla possibilità di una lettura critica, è riportare il tema a dignità di argomento di studio, mai
esplicitamente negata, ma certo sminuita, in secoli di disattenzione
Landscape management as a “sustainable agriculture” tool: the role of local administration and research in the Emilia-Romagna region (northern Italy)
No full textTowards modelling an attention-based text localization process that relies on a composite search strategy
No full textAutomatic localization of text in uncontrolled environments is still an open problem, due to the huge variability of physical appearance in the scene. This paper describes a model of visual search for text localization recasting the problem as top-down guided attentive search on the visual landscape
La vegetazione marina bentonica del Mediterraneo 1°: Sopralitorale e mesolitorale. Proposte di aggiornamento
No full textGlutamate dehydrogenase in human brain: regional distribution and properties.
No full textGlutamate dehydrogenase (GDH) activity was studied in 17 regions of six human brains. Duration and conditions of the postmortem period did not affect enzyme activity. Specific activity ranged between 103 and 377 nmoles/min/mg protein at 25 degrees C and it was 10-fold higher than that found in leukocytes. Apart from exclusively white matter regions (corpus callosum and centrum ovale), there was a moderate regional distribution (2.5-fold variation), with highest values in the inferior olive and hypothalamus, and lowest in the cerebellum and lenticular nucleus. With alpha-ketoglutarate (alpha-KG), NADH, or NH4+ as variable substrate, the apparent Km values in human brain were Km alpha-KG = 1.9 X 10(-3) M, KmNADH = 0.21 X 10(-3) M, and KmNH4+ = 28 X 10(-3) M, and in leukocytes they were Km alpha-KG = 1.7 X 10(-3) M, KmNADH = 0.24 X 10(-3) M, and KmNH4+ = 28 X 10(-3) M. The effects of cofactors, inhibitor, and pH were similar in brain and leukocyte GDH
Baseline SD-OCT characteristics of diabetic macular oedema patterns can predict morphological features and timing of recurrence in patients treated with dexamethasone intravitreal implants
No full textAims: To evaluate the timing and spectral-domain optical coherence tomography (SD-OCT) features of diabetic macular oedema (DME) recurrence according to baseline OCT patterns in patients treated with dexamethasone implant (DEX-I). Methods: This is a retrospective observational study (72 eyes/65 patients). Best-corrected visual acuity, timing of DME recurrence, and SD-OCT pattern [intraretinal cysts (IRC), IRC plus subretinal fluid (mixed), external limiting membrane (ELM), ellipsoid (IS/OS) layer integrity] were assessed at baseline and monthly until first DME recurrence. Results: Forty-two (58.3%) and 30 (41.6%) DME eyes had an IRC and mixed DME pattern at baseline, respectively. Twenty-four out of thirty mixed eyes (80%) relapsed without subretinal fluid. At baseline, mixed eyes showed similar changes in ELM and IS/OS (60 and 76.6% of eyes, respectively) versus IRC eyes (42.8 and 80.9% of eyes). After DME recurrence, more mixed eyes at baseline showed ELM and IS/OS changes (63.3 and 86.6%) than IRC eyes (50 and 76.2%). 33.3% of mixed eyes had DME recurrence at ≥ 6 months from first DEX-I implant versus 19% of IRC eyes. Conclusions: Mixed DME eyes were treated with DEX-I relapse later and more frequently without subretinal fluid than IRC eyes. SD-OCT characteristics of different DME patterns at baseline can predict morphological features and timing of DME recurrence. © 2020, The Author(s)
Functional correlates of outer retina remodeling in intermediate age-related macular degeneration using microperimetry
No full textPURPOSE. To assess the effect of drusen morphometric changes and choroidal vascular modifications on retinal sensitivity (RS) evaluated through microperimetry in intermediate age-related macular degeneration (iAMD). METHODS. A retrospective review of 18 iAMD patients (18 eyes) with a 12-month followup was performed. Eye-tracked spectral-domain optical coherence tomography was obtained, with automatic segmentation of the outer retinal layer (ORL) delineating the drusen area from the external limiting membrane to Bruch’s membrane and outer nuclear layer (ONL) thickness maps adjusted manually, as needed. Advanced retinal pigment epithelium analysis was also performed with a ZEISS PLEX Elite 900. Microperimetry obtained under mesopic conditions was overlaid with the corresponding thickness maps with Fiji software. The choroidal vascularity index (CVI) was calculated in the subfoveal b-scan and volumetric in the central 1-mm subfield. RESULTS. A reduced central ONL thickness was strongly associated with RS decline at the same region (r = 0.69, P = 0.002) and globally (r = 0.80, P < 0.001) at baseline, but also at 1 year in the central subfield (central: r = 0.70, P = 0.001). One-year subfoveal CVI variation, differently from volumetric CVI, directly influenced the central (r = 0.64, P = 0.004) and global RS (r = 0.59, P = 0.009), indicating that a CVI reduction negatively affected RS. A greater volumetric CVI within central 1-mm was associated with ORL thickening at 1 year (r = 0.61, P = 0.008). CONCLUSIONS. Progressive degeneration of the ONL is related to irreversible photoreceptor dysfunction in iAMD. Likewise, choroidal vascular modifications are associated with a significant functional decline in the central region and diffusely
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