50 research outputs found
Monitoring Acoustic Emission of Fresh Cement Paste
High strength and durability are the key factors determining the quality of concrete. To achieve the required properties, concrete mix design, and early age hydration, are the main factors affecting the performance of concrete. It is essential to monitor fresh concrete continuously through non-destructive techniques at the moment of mixing. In this study, acoustic emission (AE) has been applied to allow a continuous monitoring of the fresh cement paste. This non-destructive inspection allows the estimation of concrete properties by capturing elastic waves that are nucleated and propagate in the cement past. Moreover, ultrasonic pulse velocity (UPV), capillary pressure and heat evolution monitoring has been applied on cement paste to study the process of hydration mechanism. This study aims to check the sensitivity and effectiveness of AE technique to characterize the ongoing processes in fresh cementitious material and the possibility to contribute to a better monitoring of the process as an additional tool
An Online Induction Algorithm for Internal Contextual Grammars Using Restarting Automata
AbstractIn this paper, we propose a new algorithm to induce an internal contextual grammar from positive examples using restarting automata. Motivation comes from, real-time systems which induce the target grammar within a deadline. In our algorithm, we deal with real time inputs which are generated by internal contextual grammar. Principally grammatical inference and grammar induction are considered equivalent but there is a slight difference, in this paper we concentrate on that difference. Here initially our algorithm will concentrate on grammatical Inference but at last it will be ended up with the concept of grammar induction. In order to induce the grammar, we first obtain insertion rules by scanning an input at a particular time unit. The insertion rules are converted into contextual rules. This set of contextual rules will be a guess about the grammar without taking care of over generalization. Further we will check the correctness of the contextual rules using restarting automata for the next input string and we update the rules based on need, that is called correction phase. After getting the final time-unit/deadline as an input, the algorithm executes some steps on the induced grammar to prune the over generalization of strings. It produces the final grammar for the strings which are given within the final time-unit
Analysis of Essential Minerals in Fruit Extracts Rich in Natural Pigment and Antioxidant Properties
This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Luminescence quenching of tris(4,4ʹ-dimethyl-2,2ʹ-bipyridyl)ruthenium(II) complex with quinones in aprotic polar medium
923-928The photoinduced electron transfer interaction between a luminescent metal-ligand probe, [Ru(dmbpy)3]2+ and quinones have been investigated by absorption and fluorescence spectroscopy. The reactions of quinones with the excited state ruthenium(II) complex in DMF have been studied by luminescence quenching technique and the bimolecular quenching rate constant kq values are found close to the diffusion controlled rate. The complex has an absorption maximum of 458 nm. It shows a photoluminescence at 608 nm. The lifetime of the complex in DMF is 164 ns. The ground state absorption measurements are used to confirm the nature of quenching. Transient absorption spectral measurements are performed and the oxidative nature of quenching is confirmed. The detection of semiquinone anion radical using time resolved transient absorption spectroscopy and the linear variation of log kq vs reduction potential of the quinones confirms the electron transfer nature of the reaction
DNA repair efficiency in young hypertensive: Is lifestyle a prooxidant factor?
Background: High prevalence of hypertension (HTN) is of major concern among the middle-aged population of Kerala. Understudied in the context of HTN is oxidative damage to DNA, which is caused by free radical assaults. The modern lifestyle associated with an unhealthy diet and lack of exercise plays a key role in oxidative stress induction.
Aims and Objectives: The objective of this study was to assess the significance of oxidative stress and the effectiveness of DNA repair mechanisms in young hypertensives along with how it correlates with aspects of lifestyle.
Materials and Methods: This prospective case–control study enrolled clinically proven hypertensive patients referred from the outpatient department of Hridayalaya, Institute of Preventive Cardiology, Thiruvananthapuram, to Genetika, a research center for Cytogenetic Studies in South Kerala. Hypertensive patients (n=180) within the age group of 18–39 were compared with matched healthy controls (n=140). Associated lifestyle factors were determined.
Results: In comparison to controls, cases had noticeably higher mean levels of malondialdehyde (MDA) and mean break per cell (P<0.05). There was a difference that was statistically significant (P<0.05) between the patients and controls in terms of diet, exercise, physical activity, obesity, mental stress, alcohol, and tobacco use. On comparing MDA and mean break per cell values with lifestyle factors, a statistically significant difference was detected (P<0.05). Observed a significant positive correlation of break per cell value with MDA (P<0.05).
Conclusion: The current study demonstrated increased DNA damage and decreased DNA repair efficiency in young hypertensive and was strongly associated with lifestyle factors. Appropriate measures such as regular BP checkups, regular exercises, and abstinence from alcohol and smoking are to be taken for the prevention and control of HTN
Sudden Death in Sickle Cell Disease: An Autopsy Diagnosis
ABSTRACTSickle cell disease is a common hereditary hemoglobinopathy with high prevalence in the central and northeastern regions of India. A 24-year-old male patient with 3 days’ history of fever was brought dead to the hospital. Morphology showed clogging of blood vessels with sickled red blood cells (RBCs) in all the organs, and an autopsy diagnosis of sickle cell disease was made. As the cause may not be obvious in many cases, most patients remain undiagnosed. It is important to note the circumstances of death, gross finding, and histopathology, with hemoglobin electrophoresis if available, during autopsy to arrive at the diagnosis. This case is presented here to highlight this fact and draw attention to its pathology.How to cite this articleSheshanna N, Sethi G, Raj JA, Prakash SM, Surhonne SP. Sudden Death in Sickle Cell Disease: An Autopsy Diagnosis. J Med Sci 2017;3(4):113-115.</jats:sec
FOUR AND FIVE STAR HOTEL EMPLOYEES’ SOCIAL RELATED STRESS
This study describes and finds out to the Employees’ Stress from External Sources on Four star and Five star Hotels working place. Here Social Related Stress is belongs to External Sources of stress on Four star and Five star Hotels working place. The social relates variables are ‘No attachment with the society and social functions’ (SRS-1),‘I find it difficult to get support from others’ (SRS-2),‘Impartial treatment as to work status, income etc’ (SRS-3),‘My home affairs are affected by the events that happen at work’ (SRS-4) and ‘Not able to spend time with family members and friends’ (SRS-5). In the study to finds out through the Path RegressionAnalysis, which variables are most impact toFour star and Five star Hotels Employee
Proximate Composition and Nutritional Values of Selected Wild Plants of the United Arab Emirates
Wild plants supply food and shelter to several organisms; they also act as important sources of many nutrients and pharmaceutical agents for mankind. These plants are widely used in traditional medicinal systems and folk medicines. The present study analyzed the nutritional and proximate composition of various compounds in selected wild plants available in the UAE, viz., Chenopodium murale L., Dipterygium glaucum Decne., Heliotropium digynum Asch. ex C.Chr., Heliotropium kotschyi Gürke., Salsola imbricata Forssk., Tribulus pentandrus Forssk., Zygophyllum qatarense Hadidi. The predominant amino acids detected in the plants were glycine, threonine, histidine, cysteine, proline, serine, and tyrosine; the highest quantities were observed in H. digynum and T. pentandrus. The major fatty acids present were long-chain saturated fatty acids; however, lauric acid was only present in S. imbricata. The presence of essential fatty acids such as oleic acid, α-Linoleic acid, and linolenic acid was observed in H. digynum, S. imbricata, and H. kotschyi. These plants also exhibited higher content of nutrients such as carbohydrates, proteins, fats, ash, and fiber. The predominant vitamins in the plants were vitamin B complex and vitamin C. C. murale had higher vitamin A, whereas vitamin B complex was seen in T. pentandrus and D. glaucum. The phosphorus and zinc content were high in T. pentandrus; the nitrogen, calcium, and potassium contents were high in H. digynum, and D. glaucum. Overall, these plants, especially H. digynum and T. pentandrus contain high amounts of nutritionally active compounds and important antioxidants including trace elements and vitamins. The results from the experiment provide an understanding of the nutritional composition of these desert plant species and can be better utilized as important agents for pharmacological drug discovery, food, and sustainable livestock production in the desert ecosystem
Chitosan-TEMPO-Oxidized Nanocellulose Magnetic Responsive Patches with Hyperthermia Potential for Smart Melanoma Therapy
Melanoma
treatment is hampered by high metastasis, limited skin
penetration of drugs, and insufficient durability of the existing
polymer-based drug delivery systems. This study proposes doxorubicin
(DOX)-loaded magnetic patches comprising chitosan and TEMPO-oxidized
nanocellulose as a potential magnetic drug delivery system. Magnetic
patches were prepared by integrating superparamagnetic iron oxide
nanoparticles (IONPs) into chitosan-TEMPO-oxidized nanocellulose films
and then loaded with DOX. The magnetic, morphological, mechanical,
and degradation properties were modulated by varying chitosan-to-IONP
ratio and subsequently evaluated for magnetically triggered drug release,
hyperthermia, and in vitro biofunctionality. The
microtexture of the film surface indicates homogeneous IONP distribution
(SEM-EDX) which contributes directly to the high mechanical strength
(35–54 MPa) and magnetic sensitivity. These patches are biodegradable
and cytocompatible (MTT assay, cell adhesion, and confocal imaging)
with a 30–37% greater swelling index at tumor pH (relative
to physiological pH) and exhibit superparamagnetism with a saturation
magnetization value as high as 23.3 emu/g. The magnetic field-triggered
delivery under a static magnetic field of 50 mT produced a release
of >12% out of the total loaded amount within 1 h, while >24
h was
required to attain the same release level in the absence of magnetic
field. As per hyperthermia studies, the drug-loaded magnetic patch
elevates the temperature to the therapeutic range (>42 °C)
in
less than 7 min. The efficacy of DOX-loaded magnetic patches in treating
melanoma was evaluated using B16F10 cells, which exhibited a 79.55%
reduction in cell viability after 5 days. A facile preparation method,
magnetic hyperthermia, controlled chemotherapeutic effect, and limited
complexities make them suitable for skin cancer therapeutics
Heterosis for economic traits in coconut (Cocos nucifera L.)
Field studies conducted for a period of 12 years to assess the traits responsible for yield performance and heterosis of twelve coconut hybrids in comparison with three varieties showed that among the hybrids, GBGD x ECT recorded the highest mean yield of 127.6 nuts palm-1 year-1 and was on par with ECT x GBGD (106.9 nuts palm-1 year-1), COD x LCT (108.0 nuts palm-1 year-1) and WCT x MYD (107.6 nuts palm-1 year-1). Hybrid GBGD x PHOT recorded the highest fruit length (23.9 cm) followed by ECT x GBGD (23.3 cm). The hybrid ECT x GBGD recorded the highest values for most of the fruit characteristics viz., fruit breadth (17.3 cm), fruit weight (1180.0 g), husked fruit weight (758.0 g) and copra weight (231.1 g). The variety ‘Laccadive Ordinary’ recorded higher oil content (71.1%) compared to its hybrids, LCT x GBGD (70.8%), COD x LCT (70.0%) and LCT x COD (69.8%). Hybrids displayed substantial differences in their heterotic response for nut characters. The highest yielding hybrid, GBGD x ECT excelled its standard check by 40.8 per cent followed by LCT x COD (39.4%)
