3,649 research outputs found
CCDC 1035749: Experimental Crystal Structure Determination
No full textRelated Article: Dipankar Sahoo, Matthew G. Quesne, Sam P. de Visser, Sankar Prasad Rath|2015|Angew.Chem.,Int.Ed.|54|4796|doi:10.1002/anie.20141139
CCDC 1035747: Experimental Crystal Structure Determination
No full textRelated Article: Dipankar Sahoo, Matthew G. Quesne, Sam P. de Visser, Sankar Prasad Rath|2015|Angew.Chem.,Int.Ed.|54|4796|doi:10.1002/anie.20141139
CCDC 1035750: Experimental Crystal Structure Determination
No full textRelated Article: Dipankar Sahoo, Matthew G. Quesne, Sam P. de Visser, Sankar Prasad Rath|2015|Angew.Chem.,Int.Ed.|54|4796|doi:10.1002/anie.20141139
CCDC 1035748: Experimental Crystal Structure Determination
No full textRelated Article: Dipankar Sahoo, Matthew G. Quesne, Sam P. de Visser, Sankar Prasad Rath|2015|Angew.Chem.,Int.Ed.|54|4796|doi:10.1002/anie.20141139
Synthesis and Bioassay of Azolyl Benzothiazine Carboxamides
Get PDFCyclic sulfonamides (sultams) gained importance due to their potential pharmaceutical activity. Amongst these, 1,2-benzothiazine-1,1-dioxide and their derivatives represent the most familiar class of non-steroidal anti-inflammatory drugs (NSAIDs) available in the market. In fact, Meloxicam and Piroxicam, the members of oxicam family are used as an analgesic and anti-inflammatory drugs. Azoles are potential chemical entities with a wide range of pharmacological activities such as anticancer, antibacterial, antifungal, antiviral and antiparasitic. In continuation of our efforts to develop potential multifunctional heterocycles, we have synthesized novel azolylbenzothiazine carboxamides and studied their cytotoxic and antioxidant activities. The results of these aspects will be discussed. © 2020 Author(s).The authors Venkatapuram Padmavathi and Panga Siva Sankar are grateful to CSIR (Council of Scientific and Industrial Research), New Delhi for financial assistance under the major research project
Analysis of Thermal radiation effects on MHD flow of a nanofluid over an exponentially stretching sheet with heat and mass fluxes in the occurrence of viscous dissipation
No full textMixed-metal clusters as precursors for nanoparticle bimetallic catalysts embedded in mesoporous silica MCM-41
No full textSingle step, solvent-free processes: examples and prospects
No full textAn outline is given of some of the options now available — and likely to be of growing importance — for various of ways in which inorganic catalysts may be developed to effect industrially important chemical reactions in environmentally more acceptable means. One major goal is to devise ways of producing in situ (within the sphere of reaction) aggressive oxidants especially those that are environmentally hazardous. Two specific examples are cited: 1) one involves hydroxylamine, generated in a benign fashion, so as to effect the ammoximation of cyclohexanone to its oxime and -caprolactam; 2) the other involves the Baeyer—Villiger reaction (for converting cyclic ketones to lactones) via perbenzoic acid. The role of supported bimetallic catalysts in solvent-free hydrogenations (especially of polyenes) is also highlighted
Benign by design. New catalysts for an environmentally conscious age
No full textThere is a pressing need for: (i) cleaner fuels (free of aromatics and of minimal sulfur content) or ones that convert chemical energy directly to electricity, silently and without production of noxious oxides and particulates; (ii) chemical, petrochemical, and pharmaceutical processes that may be conducted in a one-step, solvent-free manner, and that use air as the preferred oxidant; and (iii) industrial processes that minimize consumption of energy, production of waste or the use of corrosive, explosive, volatile and nonbiodegradable materials. All these needs and other desiderata, such as the in situ production and containment of aggressive and hazardous reagents, and the avoidance of use of ecologically harmful elements, may be achieved by designing the appropriate heterogeneous inorganic catalyst, which, ideally should be cheap, readily preparable, and fully characterizable, preferably under in situ reaction conditions. A range of nanoporous and nanoparticle catalysts, designed, synthesized, characterized, and tested by the authors and their colleagues, that meet most of the stringent demands of sustainable development and responsible (clean) technologyis described. Specific examples that are highlighted include: (a) the production ofadipic acid (precursor of polyamides and urethanes) without the use of concentrated nitric acid or the production of greenhouse gases such as nitrous oxide; (b) the production of caprolactam (precursor of nylon) without the use of oleum and hydroxylamine sulfate; and (c) the terminal oxyfunctionalization of linear alkanes in air. The topic of biocatalysis and sustainable development is also briefly discussed, and a cautionary note is sounded concerning fast screening methods for the discovery of new inorganic catalysts
Molecular-sieve catalysts for the selective oxidation of linear alkanes by molecular oxygen
No full textTerminally oxidized hydrocarbons are of considerable interest as potential feedstocks for the chemical and pharmaceutical industry, but the selective oxidation of only the terminal methyl groups in alkanes remains a challenging task. It is accomplished with high efficiency and selectivity by some enzymes; but inorganic catalysts, although inferior in overall performance under benign conditions, offer significant advantages from a processing standpoint1. Controlled partial oxidation is easier to achieve with 'sacrificial' oxidants, such as hydrogen peroxide2, alkyl hydroperoxides oriodosylbenzene3, than with molecular oxygen or air. These sacrificial oxidants, themselves the product of oxidation reactions, have been used in catalytic systems involving tailored transition-metal complexes in either a homogeneous state4, 5, 6, encapsulated in molecular sieves7, 8, 9 or anchored to the inner surfaces of porous siliceous supports10. Here we report the design and performance of two aluminophosphate molecular sieves containing isolated, four-coordinated Co(III) or Mn(III) ions that are substituted into the framework and act, in concert with the surrounding framework structure, as regioselective catalysts for the oxidation of linear alkanes by molecular oxygen. The catalysts operate at temperatures between 373 K and 403 K through a classical free-radical chain-autoxidation mechanism. They are thus able to use molecular oxygen as oxidant, which, in combination with their good overall performance, raises the prospect of using this type of selective inorganic catalyst for industrial oxidation processes.<br/
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