499 research outputs found
Primena informaciono-komunikacionih tehnologija u Biblioteci Arhitektonskog fakulteta u Beogradu - Danica Radovanovic
No full textAccelerating developement of Information-Communication Technologies (ICTs) in the last decade, has been influencing on the usage of some internet services (www, mailing lists, discussion groups) and has broaden their scope from academic surroundings on educational-information centers - libraries. Library of Faculty of Architecture has started from the May 2000, to apply and use some of the internet services in purpose of education and animation of their users. This paper describes experience of one academic library in bringing in and applying modern technologies through selective structuring and difusion of information, as well as action of animation users with aim of expanding, inducing digital and information literacy. Therefore, coordinator and author of the project ArchiWeb has put in a small questionnaire , a poll among the users in purpose to understand their need and improving the work of the service
La rete di Slow Food per la valorizzazione dei prodotti locali. Una testimonianza di sviluppo autosostenibile e turistico in Herzegovina Orientale (BH)
No full textFor the recent years, Slow Food has paid its attention to the countries facing the difficulties in development and it is done through its evolution organization and Foundation called Terra Madre. When it is about the Balkans, for example, it is about a very vulnerable area in which political and economic events slowed down the development process. However, for some years already, presence of international cooperation has resulted in reconstruction of the economic background and internal relationships, starting from territorial vocations (agriculture) and valuing economic impacts and possible tourist effects. In this phase, despite animation and participation of those dealing with development in this area (in the scientific paper, direct testimonies of one to two authors is presented), there is still no full confidence established in relationships of local authorities and a way forward is made, especially with the support of the abroad interventions in order to help small agricultural producers with an intention to make a network and promotion of getting familiar with the territory through valorization of eno-gastronomy products of high quality, evidencing on the area culture. It is attempted to build the identity again as well as the recognizable brand and that is the operation of extremely great importance both for the local population and for the possible beneficiaries – tourists. The empirical case is the area of Eastern Herzegovina (the town of Trebinje is the center with six municipalities more: Ljubinje, Berkovici, Bileca, Gacko, Nevesinje and Ravno), which was treated as the pilot project on the Balkans
Affect on forecasting reliability safety engine in medical institutions; International Conference of Experimental and Numerical Investigations and NewTechnologies
No full textM. Ristic, Lj. Radovanovic, J. Perisic, I. Vasovic, G. Otic; Affect on forecasting reliability safety engine in medical institutions; International Conference of Experimental and Numerical Investigations and NewTechnologies; Zlatibor, Serbia, 29 Jun- 02 July 2021; Serbia; The book of Abstracts; ISBN: 978-86-6060-077-8; pp. 5; 202
Strategija Razvoja i promocija ruralnog turizma (Popovo polje kao turisticka destinacija)
No full textDevelopment strategy and promotion of rural tourism
No full textLo sviluppo di un territorio è originato dalle sue risorse e dalla capacità di organizzarle. In particolare nelle aree rurali si è assistito ad un abbandono progressivo della popolazione con gravi perdite sociali, culturali ed economiche. Nell’analisi, dal punto di vista metodologico, si cercherà di comparare alcune esperienze di pianificazione rurale e turistica realizzate nelle regioni adriatiche con azioni in corso sull’altra sponda dell’Adriatico, in Bosnia Erzegovina.. L’approccio fondamentale per delineare una politica di sviluppo è quello di rafforzare l’identità di questi territori coniugando il concetto di “sviluppo” con quello di “rurale”, e non solo di “agricolo”, intendendo per rurale non solo ciò che attiene esclusivamente alla campagna, alla produzione agricola, ma ciò che si riferisce all’intero “ambiente” in cui le attività si realizzano quello naturale, culturale, sociale ed economico. In questo senso le chiavi di lettura potrebbero seguire alcuni percorsi. Innanzitutto il ripristino di alcune condizioni di base per consentire l’attività agricola, come nel caso di Popovo polje. A seguire un’attenzione alla pluriattività dell’azienda agricola e della famiglia, trattandosi di piccole realtà territoriali, e di piccole imprese, ponendo attenzione a quel sistema di relazioni che intercorre tra l’attività agricola e il territorio, avendo come fulcro la centralità del nucleo familiare contadino e il suo genere di vita. Ipotizzare inoltre, come elemento evolutivo e di sviluppo, la costituzione di un sistema locale di produzione, che tenda a valorizzare le produzioni tipiche dell’area, utilizzando metodi di qualità e sistemi biologici, e creare una filiera agricola. Sostenere poi la multifunzionalità dell’agricoltura che si indirizzi verso uno sviluppo rurale integrato, potenziando il tessuto produttivo e sociale delle economie locali, e cercando occasioni di valorizzazione rurale, anche in funzione turistica e di accoglienza. Infine l’obiettivo è di consentire lo sviluppo delle aree interne, generalmente meno valorizzate rispetto a quelle costiere. Ciò è quanto si cercherà di sviluppare, fornendo alcune linee di pianificazione e promozione per l’area di Popovo polje ed esponendo i progetti realizzati e tuttora in corso
Indogenous agricultural products and biodiversity for the development of regional areas. Italy calls Bosnia and Herzegovina
No full textIn 1992, the Earth Summit in Rio de Janeiro considered "biological diversity" by introducing the term "agricultural biodiversity" or "agro-biodiversity", conceived as the set of varieties that each farmer recognizes and considers as part of the collective heritage of his land of origin. Italy holds a record of biodiversity for almost all the most important crops used for food, only partly due to physical and geographical factors. Apulia, in Southern Italy, is witnessed by numerous small details such as the countless units of land surface and quantity of agricultural products, the thousand dialects, habits and customs of the small towns. Apulia seems to be “a happy island” for biodiversity and needs to be protected with about 500 agricultural varieties between horticulture products and vegetables (“Polignano” carrots, onions from Acquaviva, and so on).
The Southern part of Bosnia and Hercegovina, region of Herzegovina, is administratively divided to Western and Eastern Hercegovina having Neretva river as natural border between two. Due to difficult post-conflict transitional period, disputable approaches undertaken in revitalization of the agriculture and ongoing political disagreements, the rich agro-biodiversity of the area has been partially lost. But regardless all difficulties, Herzegovina farmers, holding a strong cultural identity with food, helped saving from disappearance some of the oldest and most traditional products such as cheese in sack, kajmak (creamy cheese) in sack, “roga” green bean or “poljak” bean, all of them recognized by Slow Food movement to be “arc of taste” products.
The contribution, in addition to verifying the state of the art, intends to evaluate the different approaches regarding the subject outlined with regard to management and practices in Italy and in Bosnia and Herzegovina
Current and future targeted therapies for severe asthma : managing treatment with biologics based on phenotypes and biomarkers
No full textAsthma is a respiratory disorder with considerable heterogeneity in aetiology, triggers, clinical characteristics and response to therapy. This diversity reflects different inflammatory pathways that can be subdivided into clinically similar categories called phenotypes, or pathogenically comparable groups called endotypes. In recent years, a great amount of research has been dedicated to the investigation and understanding of the heterogeneity of asthma pathophysiology and to the identification of treatable traits, biomarkers, mediators and therapeutic targets. Severe asthma is defined as an uncontrolled disease despite a maximal conventional therapeutic approach. While, to date, some target therapies showing improvements in lung function, asthma symptoms and a reduction of the annual rate of exacerbations in patients with severe asthma have been already approved, other treatments are currently being studied, specifically targeting Type 2 asthma. Further progress however, is still needed to tackle the molecular pathways for non-Type 2 asthma. The aim of the present narrative review is to discuss and examine the indication, mechanisms of action and therapeutic effects of currently available and emerging biologic agents for the treatment of severe asthma
Using numerical simulation in the optimization of the finishing phases in ceramic tiles manufacturing
No full textThe Grés Porcelain stoneware surely represents a remarkable material for building inside the large family of constructive ceramics. It is appreciated in consideration of its superior properties of resistance and functionality, especially when considered respect to a relatively low cost. Billions of square meters of Grés Porcelain are produced worldwide each year, primarily in form of tiles of every dimension, thinness, color, decoration, in the way that the ceramic tile industry represents a relevant economy. But the tile manufacturing is a complex process, made by different stages and productive plants to be deeply investigated and optimized. This paper describes the use of Finite Elements for modelling and optimizing the production of Grés Porcelain tiles with special attention to the ending phases of the process, just after the treatments in kiln and realized by tool machining. The case study, used to redesign a fundamental part of a finishing machine driven by a numerical approach, is also detailed
Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study
No full textPatients affected by severe coronavirus induced disease-2019 (Covid-19) often experience hypoxemia due to alveolar involvement and endothelial dysfunction, which leads to the formation of micro thrombi in the pulmonary capillary vessels. Both hypoxemia and a prothrombotic diathesis have been associated with more severe disease and increased risk of death. To date, specific indications to treat this condition are lacking. This was a single center, investigator initiated, compassionate use, proof of concept, case control, phase IIb study (NCT04368377) conducted in the Intermediate Respiratory Care Unit of L. Sacco University Hospital in Milano, Italy. Our objective was to explore the effects of the administration of anti-platelet therapy on arterial oxygenation and clinical outcomes in patients with severe Covid-19 with hypercoagulability. We enrolled five consecutive patients with laboratory confirmed SARS-CoV-2 infection, severe respiratory failure requiring helmet continuous positive airway pressure (CPAP), bilateral pulmonary infiltrates and a pro-thrombotic state identified as a D-dimer > 3 times the upper limit of normal. Five patients matched for age, D-dimer value and SOFA score formed the control group. Beyond standard of care, treated patients received 25 μg/Kg/body weight tirofiban as bolus infusion, followed by a continuous infusion of 0.15 μg/Kg/body weight per minute for 48 hours. Before tirofiban, patients received acetylsalicylic acid 250 mg infusion and oral clopidogrel 300 mg; both were continued at a dose of 75 mg daily for 30 days. Fondaparinux2.5 mg/day sub-cutaneous was given for the duration of the hospital stay. All controls were receiving prophylactic or therapeutic dose heparin, according to local standard operating procedures. Treated patients consistently experienced a mean (SD) reduction in A-a O2 gradient of -32.6 mmHg (61.9, P = 0.154), -52.4 mmHg (59.4, P = 0.016) and -151.1 mmHg (56.6, P = 0.011; P = 0.047 vs. controls) at 24, 48 hours and 7 days after treatment. PaO2/FiO2 ratio increased by 52 mmHg (50, P = 0.172), 64 mmHg (47, P = 0.040) and 112 mmHg (51, P = 0.036) after 24, 48 hours and 7 days, respectively. All patients but one were successfully weaned from CPAP after 3 days. This was not true for the control group. No major adverse events were observed. Antiplatelet therapy might be effective in improving the ventilation/perfusion ratio in Covid-19 patients with severe respiratory failure. The effects might be sustained by the prevention and interference on forming clots in lung capillary vessels and by modulating megakaryocytes’ function and platelet adhesion. Randomized clinical trials are urgently needed to confirm these results
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