1,720,978 research outputs found
Combination of corticosteroids and adenine arabinoside in the treatment of chronic active hepatitis B
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Prognostic factors after percutaneous transhepatic biliary drainage
No full textThe authors reviewed the clinical charts and the radiographic files of 93 patients with obstructive jaundice--in 86 cases due to neoplasm--treated with PTBD. The test of differences from survival curves was used to identify the clinical parameters predictive of short survival after PTBD. The difference in survival curves was significant relative to serum indirect bilirubin (cut point: 7.6 mg%), to serum cholinesterase (cut point: 1290 mU/ml), to white blood cell counts (cut point: 8600/mm3), to blood urea nitrogen (BUN) levels (cut point: 60 mg%). Because of the marked negative prognostic value of high BUN levels, our data seem to indicate that PTBD should not be performed when severe renal insufficiency is present. Other parameters correlated with a short survival after PTBD were the histotype of metastasis (in comparison with the other ones), and large neoplastic volume (in comparison with a small and a medium ones). Through pre-PTBD radiological and laboratory data analysis, a group of patients can be selected in whom the procedure will increase neither well-being nor survival, as plotted against those patients who are likely to benefit from biliary drainage
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Interferon treatment of chronic hepatitis C patients with normal or near normal alanine-amino-transferase levels: might it be harmful rather than useful?
No full textThe efficacy of α-interferon (α IFN) in chronic hepatitis C (CHC) with normal or near normal alanine-amino-transferase (ALT) levels is not well known. Aim of this study was to evaluate the biochemical and virological response to α IFN therapy in CHC with persistently normal or near normal ALT levels. Sixteen HCV RNA positive patients affected by biopsy-proven CHC, of whom eight with persistently normal ALT levels and eight with ALT less than 1.5 times the upper reference value, monitored monthly for 6 months before treatment, were treated with recombinant α2b IFN 3 MU/t.i.w. for 6 months. Serum ALT levels were evaluated monthly during and for at least 6 months after the end of treatment. Serum HCV RNA (by nested reverse transcription-polymerase chain reaction (RT-PCR))was tested before, at the end of treatment and at the end of follow-up. HCV genotyping was performed in pretreatment sera, according to the method of Okamoto. Serum HCV RNA titre was evaluated before and at the end of treatment. Of the eight patients with normal ALT, only two (one with genotype 1a and one with 2a) cleared serum HCV RNA and maintained normal ALT levels during treatment and follow-up. All the remaining six patients were persistently HCV-RNA positive: two showed a reduction in HCV RNA titre at the end of therapy, two had no variation and two developed an increase of viraemia; two patients (both with HCV type 1b) had flare-ups during treatment and four (two type 1b, two type 2a) had relapses after the end of treatment. All the eight patients with near normal ALT remained HCV-RNA positive: three showed a reduction in HCV RNA titre, two no variation and three an increase of viraemia at the end of therapy; two patients (both infected with HCV type 1b) had flare-ups during treatment, two maintained ALT levels less than 1.5 times the upper reference limit and four normalized ALT levels during treatment but relapsed after the end of therapy. αIFN treatment induced the clearance of serum HCV RNA only in 2/16 patients; 9/16 patients showed no variation or increase of viraemia at the end of therapy; a flare-up of ALT during therapy or follow-up was frequently observed (8/16). In conclusion, αIFN treatment seems to be of little efficacy for patients with chronic hepatitis C with normal or near normal ALT levels, and may be harmful for those infected with genotype 1b
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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