198 research outputs found
Le misure contro l'esclusione sociale in Italia
No full textSeravalli G. (a cura di), Mercato del lavoro ed esclusione sociale in Emilia Romagna
Le politiche per la coesione sociale in Europa
No full textSeravalli G. (a cura di), Mercato del lavoro ed esclusione sociale in Emilia Romagna
Il progetto Futur-e
No full textFutur-e è il nome del progetto promosso da enel nel 2015 per la riqualificazione dei siti di oltre venti centrali termoelettriche in dismissione o già dismesse, situate in varie parti del territorio italiano. Il progetto, ancora in corso, ha visto fin dal principio il supporto tecnico dei Dipartimenti di Architettura e Studi Urbani e di Ingegneria Gestionale del Politecnico di Milano. A valle del lavoro svolto e nella prospettiva di innovare la collaborazione attualmente in corso, si propongono alcune riflessioni sul ruolo svolto dall’università nel processo, sulla natura e distribuzione territoriale delle centrali oggetto del progetto, sui loro paesaggi e architetture, sulla vita che si svolge al loro interno, sugli strumenti operativi per la conversione e, infine, su nuove strategie possibili di Corporate Social Responsibility per le imprese.Futur-e is the project promoted by enel in 2015 for the redevelopment of the sites of more than twenty unused or underused thermoelectric power stations in various parts of the Italian territory. Since the beginning, the still on-going project has foreseen the technical support of the Dipartimento di Architettura e Studi Urbani and of the Dipartimento di Ingegneria Gestionale of the Politecnico di Milano. On the basis of the work done and with the view to innovating the current collaboration, the authors of this issue reflect on the role of the university in the process, on the nature and the territorial distribution of the power stations included in the project, on their landscapes and architecture, on the life that takes place inside and around them, on the tools for their redevelopment, and on new possible Corporate Social Responsibility strategies for large companies
Spazi della logistica e paesaggio del petrolio nel Nord Italia. Poteri, relazioni, strategie
No full textEnergy metabolism of lymphocytes from acute stroke patients
No full textBACKGROUND AND AIMS - Systematic studies on energy metabolism of lymphocytes during ageing in male and female subjects are lacking, especially in patients with CNS Diseases. A study on cytoplasmic and mitochondrial enzymes of lymphocytes, as biological indicators of energy
metabolism, was performed in healthy blood donors and in patients with acute strok
Functional compensation in incipient Alzheimer's disease
No full textAim of this study was to investigate the functional compensation mechanism in incipient Alzheimer's disease (AD). Seventeen elderly healthy subjects and nine amnestic MCI patients with incipient AD underwent brain MR scan and 99mTc ECD SPECT. We processed all images with SPM2, we created t maps, showing the wholebrain GM atrophy and functional changes, and we properly masked them with each other in order to assess relatively preserved perfusion or depression. Incipient AD showed GM atrophy in the medial temporal and temporoparietal lobes, in the insula and in the retrosplenial cortex, and GM hypoperfusion in the medial temporal and temporoparietal lobes. Relatively preserved perfusion, we could hypothesize to be compensatory in the setting of neuronal loss, was found in the posterior cingulate, in the head of the hippocampus, in the amigdala, and in the insula bilaterally, while functional depression occurred in bilateral parahippocampal gyri. In AD, a perfusional compensatory mechanism takes place in the neocortex, while perfusional depression occurs in the medial temporal lobe. These results help understand the reactive phenomena induced by the brain to try and counteract the pathological changes of AD.A. Caroli, C. Geroldi, F. Nobili, L.R. Barnden, U.P. Guerra, M. Bonetti, G.B. Frison
Cerebral perfusion correlates of conversion to Alzheimer's disease in amnestic mild cognitive impairment
No full textThe original publication can be found at www.springerlink.comObjective Aim of this study was to find cerebral perfusion correlates of conversion to dementia in patients with amnestic MCI. Methods 17 healthy subjects (age = 69 ± 3, 9 females), and 23 amnestic MCI patients (age = 70 ± 6, 10 females) underwent brain MR scan and 99mTc ECD SPECT. Conversion to AD was ascertained on average 19 ± 10 months after baseline: 9 had converted (age = 69 ± 3, 4 females), and 14 had not (age = 71 ± 8, 6 females). We processed SPECT images with SPM2 following an optimized protocol and performed a voxel-based statistical analysis comparing amnestic MCI patients converted to AD and non-converted to dementia vs controls. We assessed the effect of gray matter atrophy on the above results with SPM2 using an optimized Voxel-Based Morphometry (VBM) protocol.We compared significant hypoperfusion with significant atrophy on a voxel-byvoxel basis. Results In comparison with normal controls, amnestic MCI patients who converted to AD showed hypoperfusion in the right parahippocampal gyrus and left inferior temporal and fusiform gyri,whereas those who did not convert showed hypoperfusion in the retrosplenial cortex, precuneus and occipital gyri, mainly on the left side.We found no overlap between significant atrophy and significant hypoperfusion regions. Conclusions Parahippocampal and inferior temporal hypoperfusion in amnestic MCI patients appears as a correlate of conversion to AD; hypoperfusion in the retrosplenial cortex is involved in memory impairment but does not seem the key prognostic indicator of conversion to dementia.A. Caroli, C. Testa, C. Geroldi, F. Nobili, L. R. Barnden, U. P. Guerra, M. Bonetti and G. B. Frison
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