1,571 research outputs found
End-to-End QoS Support for a Medical Grid Service Infrastructure
No full textQuality of Service support is an important prerequisite for the adoption of Grid technologies for medical applications. The GEMSS Grid infrastructure addressed this issue by offering end-to-end QoS in the form of explicit timeliness guarantees for compute-intensive medical simulation services. Within GEMSS, parallel applications installed on clusters or other HPC hardware may be exposed as QoS-aware Grid services for which clients may dynamically negotiate QoS constraints with respect to response time and price using Service Level Agreements. The GEMSS infrastructure and middleware is based on standard Web services technology and relies on a reservation based approach to QoS coupled with application specific performance models. In this paper we present an overview of the GEMSS infrastructure, describe the available QoS and security mechanisms, and demonstrate the effectiveness of our methods with a Grid-enabled medical imaging service
ACTIVATION OF THE HUMAN-LEUKOCYTE PROTEINASES ELASTASE AND CATHEPSIN-G BY VARIOUS SURFACTANTS
No full textWenzel H, FELDMANN A, ENGELBRECHT S, Tschesche H. ACTIVATION OF THE HUMAN-LEUKOCYTE PROTEINASES ELASTASE AND CATHEPSIN-G BY VARIOUS SURFACTANTS. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 1990;371(2):721-724
Dimidiogalumna Engelbrecht 1972
No full textGenus <i>Dimidiogalumna</i> Engelbrecht, 1972 (<i>b</i>) <p> Type species: <i>Dimidiogalumna villiersensis</i> Engelbrecht, 1972 (<i>b</i>), p. 141</p> <p> Without sexual dimorphism in prodorsum and notogaster, notogaster rounded posteriorly in both genders. Body surface without strongly developed sculpture or ornamentation, or pteromorphs striate. Rostrum rounded. Lamellar lines present, long, thin, curving backwards at ventral end, sublamellar lines absent. Rostral setae medial to lamellar lines and distanced from them. Lamellar setae lateral to lamellar lines. Bothridial setae clavate, fusiform, lanceolate. Dorsosejugal suture absent or present, postanal porose area present. Notogastral setae represented by 10 pairs of alveoli, one pair on pteromorphs. Octotaxic system represented by porose areas, saccules absent, one pair of <i>Aa</i>. Median pore present in females and males, undivided. Pteromorphs clearly bilobed. Without thorn-like structures behind pteromorphs, dark band anterior to genital aperture and anal and adanal neotrichy. Adanal lyrifissures located close and lateral to anal aperture. Leg tarsi with three claws. Leg setae not modified.</p> <p> Statement of monophyly: Non-monophyletic—see Note 4.3 in <i>Taxonomic notes</i> section</p> <p>Distribution: Ethiopian, Oriental and southern Palaearctic regions</p> <p>Known species: five species</p>Published as part of <i>Ermilov, Sergey G. & Klimov, Pavel B., 2017, Generic revision of the large-winged mite superfamilY Galumnoidea (Acari, Oribatida) of the world, pp. 1-72 in Zootaxa 4357 (1)</i> on page 20, DOI: 10.11646/zootaxa.4357.1.1, <a href="http://zenodo.org/record/1066658">http://zenodo.org/record/1066658</a>
Carinogalumna Engelbrecht 1973
No full textGenus Carinogalumna Engelbrecht, 1973 (= Paracarinogalumna Mahunka, 1998 —syn.: Subías 2004, Pseudogalumna Pérez-Íñigo & Baggio, 1994 —syn.: Subías 2004)—see Note 3.3 in Taxonomic notes section Type species: Carinogalumna montana Engelbrecht, 1973, p. 396 4. Two previous synonymies, Angulogalumna Grishina, 1981 (= Cuspidogalumna Starý, 2005) and Galumna (Galumna) Heyden, 1826 (= Kinezogalumna Аoki & Hu, 1993), were made online in electronically distributed works (Subías 2004, online versions 2008, 2009, respectively). Unfortunately, these works do not meet the ICZN criteria of publication (Аrt. 8.5). Here we attribute these synonyms and the resulting new combinations to L.S. Subías. Without sexual dimorphism in prodorsum and notogaster, notogaster rounded posteriorly in both genders. Body surface without strongly developed sculpture or ornamentation. Rostrum pointed or with trapezoid ledge. Lamellar lines present, long, costula-like, straight (directed to rostrum) or curving backwards at ventral end, sublamellar lines absent or present, long, thin, curving backwards at ventral end. Rostral setae close to ends of lamellar lines (if they straight) or medial to lamellar lines and distanced from them. Lamellar setae usually medial, exceptionally lateral to lamellar lines. Bothridial setae setiform, clavate, fusiform, lanceolate. Dorsosejugal suture and postanal porose area absent or present. Notogastral setae represented by 10 pairs of alveoli, one pair on pteromorphs. Octotaxic system represented by porose areas, saccules absent, one pair of Aa. Median pore absent or present in females and males, undivided. Pteromorphs clearly bilobed. Without thorn-like structures behind pteromorphs, dark band anterior to genital aperture and anal and adanal neotrichy. Adanal lyrifissures located close and lateral to anal aperture. Leg tarsi with three claws. Leg setae not modified. Statement of monophyly: Non-monophyletic—see Note 4.3 in Taxonomic notes section Distribution: Pantropical region (except Australian region) Known species: five speciesPublished as part of Ermilov, Sergey G. & Klimov, Pavel B., 2017, Generic revision of the large-winged mite superfamilY Galumnoidea (Acari, Oribatida) of the world, pp. 1-72 in Zootaxa 4357 (1) on pages 17-19, DOI: 10.11646/zootaxa.4357.1.1, http://zenodo.org/record/106665
SEPARATION OF THE HUMAN-LEUKOCYTE ENZYMES ALANINE AMINOPEPTIDASE, CATHEPSIN-G, COLLAGENASE, ELASTASE AND MYELOPEROXIDASE
No full textENGELBRECHT S, PIEPER E, MACARTNEY HW, RAUTENBERG W, Wenzel H, Tschesche H. SEPARATION OF THE HUMAN-LEUKOCYTE ENZYMES ALANINE AMINOPEPTIDASE, CATHEPSIN-G, COLLAGENASE, ELASTASE AND MYELOPEROXIDASE. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 1982;363(1):305-316
Developing international research capacity and capability.
No full textPlease cite as follows:Spolander, G. & Engelbrecht, L. K. 2012. Developing International Research Capacity and Capability. Policy Dialogue Workshop – Exchange and Capacity Building Measures. EU conference. Addis Ababa: Ethiopia, 23-24 October 2012.Power point slidesOriginal work
MAORI AND THE INFORMATION WORKFORCE, 1991-2001
No full textThis paper documents the size, composition and changes in New Zealand's information workforce over the period 1991 to 2001. The estimates are disaggregated into Maori/non-Maori, by gender, and by major occupational categories. The absolute as well as relative size of the information workforce has continued to grow during the period, though the relative growth rate is a lot lower than during the 1980s. While the findings for women in general are encouraging, those for Maori, and especially Maori men, are less so. Maori remain underrepresented in the information workforce. Although their participation has increased, the gaps in participation rates between Maori and non-Maori have changed little.Labor and Human Capital,
Unusual bending patterns of spermidine3+ bound to DNA double helix
No full textNatural polyamines play a fundamental role in the cell cycle. Despite being recognized as the most abundant organic counterions of DNA in the cell nucleus, their interactions with DNA have not been fully characterized. In a recent work [S. Perepelytsya, T. Vasiliu, A. Laaksonen, L. Engelbrecht, G. Brancato, and F. Mocci, J. Molec. Liq. 389, 122828 (2023)], we have shown how the interactions between spermidine(3+) and the DNA double helix induce significant conformational variations in the polyamine molecule. Specifically, we found that DNA induces conformations that are not observed in solution. Following that study, we present here a detailed investigation of the most compact conformation of the polyamine, analyzing its connection to the interaction with the DNA duplex. The analysis reveals that anomalous bent conformations of the spermidine(3+) molecule result from the interaction of all three amino groups of the polyamine with the DNA phosphate groups on the minor groove side of the double helix. The changes in dihedral angles of the bent spermidine(3+) molecule can be explained in terms of conformational transformations of six- and seven-membered rings, analogous to cyclohexane and cycloheptane. The analysis of the position of spermidine(3+) molecule along the DNA surface reveals a sequence specificity of this binding mode with a marked preference for the narrow minor groove of A-tracts. The formation of the anomalous bent conformations of spermidine(3+) in the complex with the DNA double helix is expected to be of paramount importance in understanding the mechanisms underlying DNA's biological function
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